Results 111 to 120 of about 7,413,780 (315)
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
A computing task ergonomic risk assessment tool for assessing risk factors of work related musculoskeletal disorders [PDF]
, 2018 Observation method remains to be the most widely applied method in assessing exposure to risk factors for work-related musculoskeletal disorders (WMSDs) related to office works because it is inexpensive and applicable to wide range of office jobs ...
Mohamad, Siti Shafika
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Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Bracknell Meteorological Office [PDF]
The Bracknell (U.K.) Meteorological Office runs a global weather model twice a day, providing the following data: surface and radiosonde; aircraft reports; and satellite soundings and wind. A human forecast is made every six hours.
Flood, Colin R.
core +1 more source
Norms, Law and the Impeachment Power [PDF]
, 2017 [Excerpt] Most experts believe that, while a president can be criminally prosecuted after leaving office, he cannot be prosecuted while he is president.
Greabe, John M.
core +2 more sources
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
THE PUBLIC OFFICER - THE ACTIVE SUBJECT OF A CRIME [PDF]
Challenges of the Knowledge Society, 2011 The present study intends to analyze the active subject of the crime committed by an individual - the public officer, for example - during his daily duty program or with reference to the attributions he has versus the public office he holds, in the light
NICOLETA-ELENA BUZATU
doaj
New estimates of the risk and duration of registered unemployment in urban Russia [PDF]
, 2005 This paper examines whether deregistration from the employment office decreases unemployment duration. The study is based on Russian individual-level data from the Public Employment Office of Rostov-on-Don combined with information from the 2000 ...
Nivorozhkin, A.
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