Results 131 to 140 of about 1,046,670 (169)

Per- and Polyfluoroalkyl Substances During Pregnancy and Gestational Diabetes: The Environmental Influences on Child Health Outcomes (ECHO) Cohort. [PDF]

Diabetes Care
Starling AP, Burjak M, Nzegwu AW, Xun X, Adgate JL, Barrett ES, Bennett DH, Chatzi L, Colicino E, Dabelea D, Dunlop AL, Eick SM, Farzan SF, Ferrara A, Fleisch AF, Geiger SD, Hedderson MM, Kahn LG, Karagas MR, Kelly RS, Liang D, Lin PI, O'Connor TG, Padula AM, Peterson AK, Romano ME, Sathyanarayana S, Zhu Y, Valvi D, ECHO Cohort Consortium* .   +29 more
europepmc   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Retraction: <i>In vitro</i> anticancer effects of JI017 on two prostate cancer cell lines involve endoplasmic reticulum stress mediated by elevated levels of reactive oxygen species. [PDF]

Front Pharmacol
Frontiers Editorial Office.
europepmc   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Correction: Establishing percentiles for phase angle, skeletal muscle mass index, and muscle-to-fat ratio in Brazilian adolescents: a bioelectrical impedance analysis study with 59,000 participants. [PDF]

Front Nutr
Frontiers Production Office.
europepmc   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source

[Expression of Concern] miR-148a inhibits cell proliferation and migration through targeting ErbB3 in colorectal cancer. [PDF]

Oncol Lett
Zhao W, Zheng J, Wei G, Yang K, Wang G, Sun X.   +5 more
europepmc   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source