Results 141 to 150 of about 7,413,780 (315)

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Global Employment Trends for Youth: October 2008 [PDF]

open access: yes, 2008
[Excerpt] An intensified focus on youth at the international level in recent years has brought a greater understanding of youth labour markets and led to development of a growing number of national action plans for youth employment as well as other more ...
International Labour Office
core   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

The Health Officer's Tenure of Office [PDF]

open access: yesAmerican Journal of Public Health and the Nations Health, 1929
openaire   +2 more sources

Labour Migration and Development: ILO Moving Forward [PDF]

open access: yes, 2013
[Excerpt] This document has been prepared for the Tripartite Technical Meeting on Labour Migration, to be held in Geneva from 4 to 8 November 2013.
International Labor Office
core   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Adaptive Resonance Theory [PDF]

open access: yes, 1993
Air Force Office of Scientific Research (F49620-92-J-0225); National Science Foundation (IRI-90-00530); Office of Naval Research (N00014-91-J ...
Carpenter, Gail A., Grossberg, Stephen
core   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Figure-Ground Separation [PDF]

open access: yes, 1994
Air Force Office of Scientific Research (F49620-92-J-0499); Advanced Research Projects Agency (ONR N00014-92-J-4015); Office of Naval Research (N00014-91-J ...
Grossberg, Stephen
core   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

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