Results 91 to 100 of about 660,630 (306)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

A proposal of method for module commonization in product family (Application of diversity analysis method to servo motors and verification of its effectiveness)

open access: yesNihon Kikai Gakkai ronbunshu
A method for both quality improvement and design efficiency is required to meet diversifying customer requirements and human resource development. Especially in the case of production approach with customization, such as in industrial equipment, a design
Naoki INOUE   +8 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Solar-optimum design principles for office buildings

open access: yesMATEC Web of Conferences, 2017
New concept of passive cooling of buildings is presented in this article.. In order to achieve that, it is planned to define three basic elements of the building concept – shape of building, sun movement and sustainability of the building.
Borodinecs Anatolijs   +3 more
doaj   +1 more source

Productivity, Satisfaction, Work Environment and Health after Relocation to an Activity-Based Flex Office-The Active Office Design Study. [PDF]

open access: yesInt J Environ Res Public Health, 2021
Öhrn M   +8 more
europepmc   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Public Engagement Issue Area Networks: Design Thinking Series, Workshop 1, Team 8: Diversity

open access: yes, 2013
Office for Public Engagement; College of Design. (2013). Public Engagement Issue Area Networks: Design Thinking Series, Workshop 1, Team 8: Diversity.
College of Design   +1 more
core  

Determination of the rate of corrosion of the main structural material of the grids of capillary phase separators

open access: yesАвіаційно-космічна техніка та технологія
The subject of this study is the corrosion processes that occur in the fuel tanks of spacecraft with a long service life, the engines of which operate on chemically aggressive fuel components (FC): nitrogen tetroxide (NT) and asymmetric dimethylhydrazine
Oleksandr Minai
doaj   +1 more source

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