Results 91 to 100 of about 17,119,270 (336)
Demonstrating adequate safety for a concrete column exposed to fire, using probabilistic methods [PDF]
, 2019 Demonstrating adequate safety for exceptional designs and new design applications requires an explicit evaluation of the safety level, considering the uncertainties associated with the design. The recently published PD 7974-7:2019 provides five routes to
Elhami Khorasani, Negar +3 more
core
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Flood Frequency Estimation in Northern Sparse Data Regions: Completion Report [PDF]
, 1974 The primary objective of this project was to complete development of an arctic hydrologic model and to evaluate its usefulness in generating information useful for a design tool in estimation of peak flow discharges.
Carlson, Robert F., Fox, Patricia
core
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Detached house with design office [PDF]
, 2015 Předmětem bakalářské práce je novostavba rodinného domu s projekční kanceláří v Uherském Brodě. Rodinný dům je umístěn na rovinném pozemku kousek od centra města. Dům je dvoupodlažní.
Horňáková, Veronika
core
Visualization of metabolic interaction networks in microbial communities using VisANT 5.0 [PDF]
, 2016 The complexity of metabolic networks in microbial communities poses an unresolved visualization and interpretation challenge. We address this challenge in the newly expanded version of a software tool for the analysis of biological networks, VisANT 5.0 ...
Chang, Yi-Chien +5 more
core +4 more sources
Fetal Brain Tumor Harboring a Unique ROCK1::BRAF Fusion
Pediatric Blood &Cancer, EarlyView.
Marllon Cindra Sant'Ana +8 more
wiley +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
, 2020 Zero energy high rise buildings aim for a more sustainable urban environment, by reducing energy use demand, producing energy from renewable systems, but at the same time maintaining high thermal comfort levels.
E. D. Giouri, M. Tenpierik, M. Turrin
semanticscholar +1 more source