Results 111 to 120 of about 660,630 (306)
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
User Centered Design In Office Furniture Industry In Turkey: Office Chair Example
, 2014 Tez (Yüksek Lisans) -- İstanbul Teknik Üniversitesi, Fen Bilimleri Enstitüsü, 2014Thesis (M.Sc.) -- İstanbul Technical University, Instıtute of Science and Technology, 2014Bu tez çalışmasında kullanıcı odaklı tasarım açısından ofis mobilya sektörü ele ...
Öktem, Bige
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Designing for active office work
, 2021 This doctoral dissertation, anchored in the fields of Human-Computer Interaction (HCI) and design research, addresses the following primary research question: How can interaction design research contribute to stimulating physical activity in the office environment?
openaire +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
United States Office of Saline Water Report 277
, 1967 Report issued by the Office of Saline Water discussing the conceptual design of a 50 MGD water desalination plant. Numerous design concepts are presented, along with detailed descriptions and comparisons of the different designs.
Hunter, J. A. +2 more
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Accepted office design, elevation to Bent Street
, 2023 Item 3633 - 1 Album: New offices, CSR office building under construction, Bent Street, Sydney, exterior views, interior views, laboratories, drawing office and board ...
Architect: Harold O. Jackson +1 more
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Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
New working environments. Smart and employee-centered office design
, 2016 LAUREA MAGISTRALETra le conseguenze della globalizzazione vi è anche il cambiamento del modo di lavorare. La vita lavorativa delle persone presenta ora un nuovo approccio, chiamato lavoro intelligente (smart working), il quale prevede le opzioni di ...
YENEL, GIZEM
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