Results 121 to 130 of about 660,630 (306)
Correction: The work environment pilot: An experiment to determine the optimal office design for a technology company. [PDF]
PLoS One, 2020 Pitchforth J +3 more
europepmc +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Towards a kansei-based user modeling methodology for eco-design [PDF]
, 2013 We propose here to highlight the benefits of building a framework linking Kansei Design (KD), User Centered Design (UCD) and Eco-design, as the correlation between these fields is barely explored in research at the current time.
AOUSSAT, Améziane +2 more
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Accepted office design, elevation to O'Connell Street
, 2023 Item 3633 - 1 Album: New offices, CSR office building under construction, Bent Street, Sydney, exterior views, interior views, laboratories, drawing office and board ...
Architect: Harold O. Jackson +1 more
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Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Engineering Solutions to Optimise the Design of Carbon-Neutral Tall Office Buildings
, 2009 Energy efficiency differs by building use and type as well as prevailing climatic conditions. This study examines the energy efficiency of tall office buildings in a Mediterranean climate by investigating the energy balance for a typical level (or storey)
Pitman, Mark, King, Andrew
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The design requirements of office systems
ACM Transactions on Information Systems, 1984 BRACCHI, GIAMPIO, PERNICI, BARBARA
openaire +3 more sources
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Jointing design in open plan system for office [PDF]
, 2008 Most modern offices use open plan office system due to the flexibility of the product. The open plan system (OPS) can be customized from low screen to high screen and can be installed and dismantled according to the office needs.
Abdul Rahman, Ahmad Rizal +3 more
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Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source