Function‐driven design of a surrogate interleukin‐2 receptor ligand
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
The Progress of R in Romanian Official Statistics [PDF]
The present paper exposes an overview of the state-of-the-art of R statistical software in the official statistics in Romania, predominantly in the social statistics.
Ana Maria Dobre, Cecilia Roxana Adam
doaj
Top-income adjustments and official statistics on income distribution: the case of the UK. [PDF]
Jenkins SP.
europepmc +1 more source
User innovation and the market [PDF]
This paper proposes a way of including in official statistics consumers as user innovators who modify or develop products for their own use. The issue addressed is the role of the market in the definition of innovation in the OECD/Eurostat Oslo Manual ...
Gault, Fred
core
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
The Future of Official Statistics
Erica L. Groshen
doaj +1 more source
Neurocysticercosis in Latin America: Current epidemiological situation based on official statistics from four countries. [PDF]
Rodríguez-Rivas R +8 more
europepmc +1 more source
Are All Quality Dimensions of Equal Importance when Measuring the Perceived Quality of Official Statistics? Evidence from Spain [PDF]
Àlex Costa +2 more
openalex +1 more source
Interoperable Visualization Framework Towards Enhancing Mapping and Integration of Official Statistics [PDF]
Haitham Zeidan +2 more
openalex +1 more source
Online and official price indexes: Measuring Argentina's inflation [PDF]
Prices collected from online retailers can be used to construct daily price indexes that complement official statistics. This paper studies their ability to match official inflation estimates in five Latin American countries, with a focus on Argentina ...
Cavallo, Alberto F.
core +1 more source

