Results 161 to 170 of about 716,395 (290)

Influence of Zn2+ and Oxygen Supply on Malic Acid Production and Growth of Aspergillus oryzae

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Malic acid is a valuable platform chemical traditionally derived from fossil‐based resources. Microbial cultivation with Aspergillus oryzae offers a sustainable alternative based on renewable feedstocks. In this study, a well‐established minimal medium for malic acid production, commonly used in previous research to ensure reproducibility, was
Lukas Hartmann, Anke Neumann, Dirk Holtmann, Katrin Ochsenreither   +3 more
wiley   +1 more source

AI-powered BlindSpot VisionGuide system on raspberry Pi for enhancing independence of visually impaired users. [PDF]

Sci Rep
Sudha M, Swaminathan S, Suba M, Suyamburajan A.   +3 more
europepmc   +1 more source

Development of Raman Spectroscopy and Machine Learning Methods for Protein Aggregate Quantification: Application to BSA in Chromatographic Processes

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Protein aggregation poses a significant risk to biopharmaceutical product quality, as even minor amounts of oligomeric species can compromise efficacy and safety. Rapid and reliable detection of protein aggregates thus remains a major challenge in biopharmaceutical manufacturing.
Jakob Heyer‐Müller, Robin Schiemer, Lars Robbel, Michael Schmitt, Jürgen Hubbuch   +4 more
wiley   +1 more source

Evaluation of non-ophthalmologist-led and offline AI-assisted models for diabetic retinopathy screening in India: a pragmatic diagnostic accuracy study. [PDF]

BMJ Open
Chauhan A, Vale L, Kankaria A, Tigari B, Kumar S, Yadav M, Kumar L, Kaur G, Bhadada SK, Gupta V, Duggal M.   +10 more
europepmc   +1 more source

Transfer Learning Approaches in Bioprocess Engineering: Opportunities and Challenges

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Transfer learning (TL) has recently emerged as a promising approach to overcoming one of the key limitations of bioprocess engineering: data scarcity. By leveraging knowledge from one bioprocess to another, TL allows existing models and data sets to be reused efficiently, accelerating process development, improving prediction accuracy, and ...
Daniel Barón Díaz, Anna‐Lena Drommershausen, Alexander Grünberger, Dirk Holtmann   +3 more
wiley   +1 more source

LG-H-PPO: offline hierarchical PPO for robot path planning on a latent graph. [PDF]

Front Robot AI
Han X.
europepmc   +1 more source

Real‐Time Monitoring of In Vitro Transcription for Production of mRNA Using Raman Spectroscopy

Biotechnology and Bioengineering, EarlyView.
Schematic depicting the workflow for model building and validation using Raman spectroscopy for real‐time monitoring of IVT. ABSTRACT The success of COVID‐19 mRNA vaccines showcased the transformative potential of this adaptable, plug‐and‐play, and rapid response platform.
Julia Puppin Chaves Fulber, Xingge Xu, Hadi El Radi, Kevin Grollier, Amine A. Kamen   +4 more
wiley   +1 more source

Center of Pressure Measurement Sensing System for Dynamic Biomechanical Signal Acquisition and Its Self-Calibration. [PDF]

Sensors (Basel)
Li N, Zhang J, Zhang K.
europepmc   +1 more source

Raman Spectroscopy–Based Glucose Feed Control Automates Malic Acid Fermentation

Biotechnology and Bioengineering, EarlyView.
Raman spectroscopy enables automated, closed‐loop glucose feeding for malic acid production with Ustilago trichophora. Online PLS regression of glucose and malic acid provides input for PID control to maintain 20 g/L glucose. The feed is dynamically adjusted and stopped in response to metabolic demand and product inhibition, demonstrating practical ...
Luca Antonia Grebe, Katharina Hürter, Dominik Engel, Alexander Walter Wilhelm Echtermeyer, Mafalda S. Santos, Laurin Röder, Valentin Steier, Jörn Viell, Jørgen Barsett Magnus   +8 more
wiley   +1 more source

Research on missing value prediction of measured ERT data for coal mine based on a GRNN algorithm. [PDF]

PLoS One
Wang P, Yi X, Wang S.
europepmc   +1 more source