Aspectos biomédicos y epidemiológicos del accidente ofídico en el departamento del Cauca, Colombia, 2009-2018 [PDF]
Biomédica: revista del Instituto Nacional de Salud, 2021 Introducción. El ofidismo en Colombia es un problema de salud pública, lo cual se hace evidente al examinar los datos epidemiológicos a nivel latinoamericano, pues el país ocupa el tercer lugar en número de accidentes ofídicos después de Brasil y México.
María José Sevilla-Sánchez +2 more
doaj +2 more sources
Isolation and Functional Characterization of an Acidic Myotoxic Phospholipase A2 from Colombian Bothrops asper Venom [PDF]
Toxins, 2017 Myotoxic phospholipases A2 (PLA2) are responsible for many clinical manifestations in envenomation by Bothrops snakes. A new myotoxic acidic Asp49 PLA2 (BaCol PLA2) was isolated from Colombian Bothrops asper venom using reverse-phase high performance ...
Silvia Posada Arias +7 more
doaj +2 more sources
Inhibition of a Snake Venom Metalloproteinase by the Flavonoid Myricetin [PDF]
Molecules, 2018 Most of the snakebite envenomations in Central and South America are caused by species belonging to Bothrops genus. Their venom is composed mainly by zinc-dependent metalloproteinases, responsible of the hemorrhage characteristic of these envenomations ...
Lina María Preciado +4 more
doaj +2 more sources
Snake venomics of Bothrops punctatus, a semiarboreal pitviper species from Antioquia, Colombia [PDF]
PeerJ, 2014 Bothrops punctatus is an endangered, semi-arboreal pitviper species distributed in Panamá, Colombia, and Ecuador, whose venom is poorly characterized.
Maritza Fernández Culma +3 more
doaj +3 more sources
MipLAAO, a new L-amino acid oxidase from the redtail coral snake Micrurus mipartitus [PDF]
PeerJ, 2018 L-amino acid oxidases (LAAOs) are ubiquitous enzymes in nature. Bioactivities described for these enzymes include apoptosis induction, edema formation, induction or inhibition of platelet aggregation, as well as antiviral, antiparasite, and antibacterial
Paola Rey-Suárez +5 more
doaj +3 more sources
Sulfur Compounds as Inhibitors of Enzymatic Activity of a Snake Venom Phospholipase A2: Benzyl 4-nitrobenzenecarbodithioate as a Case of Study [PDF]
Molecules, 2020 Snakebite is a neglected disease with a high impact in tropical and subtropical countries. Therapy based on antivenom has limited efficacy in local tissue damage caused by venoms. Phospholipases A2 (PLA2) are enzymes that abundantly occur in snake venoms
Isabel Henao Castañeda +3 more
doaj +2 more sources
Accidente ofídico en el departamento de Nariño, Colombia: análisis retrospectivo, 2008-2017 [PDF]
Biomédica: revista del Instituto Nacional de Salud, 2019 Introducción. El ofidismo es un relevante problema de salud pública y, en Colombia, se incluyó como un evento de notificación obligatoria desde el año 2004.
María José Sevilla-Sánchez +4 more
doaj +2 more sources
Interactions between Triterpenes and a P-I Type Snake Venom Metalloproteinase: Molecular Simulations and Experiments [PDF]
Toxins, 2018 Small molecule inhibitors of snake venom metalloproteinases (SVMPs) could provide a means to rapidly halt the progression of local tissue damage following viperid snake envenomations.
Lina María Preciado +3 more
doaj +2 more sources
Synthetic Inhibitors of Snake Venom Enzymes: Thioesters Derived from 2-Sulfenyl Ethylacetate [PDF]
Pharmaceuticals, 2019 Snakebite envenomings are a global public health issue. The therapy based on the administration of animal-derived antivenoms has limited efficacy against the venom-induced local tissue damage, which often leads to permanent disability.
Isabel C. Henao Castañeda +2 more
doaj +2 more sources
Bioactive Compounds Isolated from Marine Bacterium Vibrio neocaledonicus and Their Enzyme Inhibitory Activities [PDF]
Marine Drugs, 2019 Marine organisms are recognized as a source of compounds with interesting biological activities. Vibrio neocaledonicus has been reported on for its high effectiveness against corrosion in metals but it has been little studied for its chemical and ...
Isabel Gómez-Betancur +6 more
doaj +2 more sources