Results 31 to 40 of about 28,063 (214)

Online Convex Optimization with Binary Constraints

, 2021
We consider online optimization with binary decision variables and convex loss functions. We design a new algorithm, binary online gradient descent (bOGD) and bound its expected dynamic regret.
Callaway, Duncan S., Lesage-Landry, Antoine, Taylor, Joshua A.   +2 more
core   +1 more source

The Promises and Perils of Open Government Data (OGD)

The Journal of Community Informatics, 2012
This editorial essay presents an overview of the contributions in the Special Issue. It also raises critical questions for further research and thinking about Open Government Data.
Tim G. Davies, Zainab Ashraf Bawa
openaire   +1 more source

Contribution of ginsenosides Rg1, Rb1 to the neuroprotective effect of Panax notoginseng in mouse organotypic hippocampal slice cultures exposed to oxygen and glucose deprivation

Vietnam Journal of Science, Technology and Engineering, 2022
We previously demonstrated that Panax notoginseng (pNG) root extract treatments exerted neuroprotective effects on brain injuries using middle cerebral artery occlusion in mice.
Nguyen Thi Thanh Loan, Le Thi Xoan, Pham Thi Nguyet Hang, Nguyen Van Tai   +3 more
doaj   +1 more source

Non-stationary Stochastic Optimization [PDF]

, 2013
We consider a non-stationary variant of a sequential stochastic optimization problem, in which the underlying cost functions may change along the horizon.
Besbes, O., Gur, Y., Zeevi, A.
core   +2 more sources

Tracking the Evolution of OGD Portals: A Maturity Model [PDF]

, 2017
Since its inception, open government data (OGD) as a free re-useable object has attracted the interest of researchers and practitioners, civil servants, citizens and businesses for different reasons in each target group. This study was designed to aggregate the research outcomes and developments through the recent years towards illustrating the ...
Charalampos Alexopoulos, Vasiliki Diamantopoulou, Yannis Charalabidis   +2 more
openaire   +2 more sources

Crosstalk between m6A mRNAs and m6A circRNAs and the time-specific biogenesis of m6A circRNAs after OGD/R in primary neurons

Epigenetics, 2023
Cerebral ischaemiareperfusion injury is an important pathological process in nervous system diseases during which neurons undergo oxygenglucose deprivation and reoxygenation (OGD/R) injury.
Chi Zhang, Huan Jian, Shenghui Shang, Lu Lu, Yongfu Lou, Yi Kang, Hong Bai, Zheng Fu, Yigang Lv, Xiaohong Kong, Xueying Li, Shiqing Feng, Hengxing Zhou   +12 more
doaj   +1 more source

Apelin-13 Protects Neurons by Attenuating Early-Stage Postspinal Cord Injury Apoptosis In Vitro

Brain Sciences, 2022
Apelin is a 77-amino-acid peptide that is an endogenous ligand for the G protein-coupled receptor APJ (Apelin receptor, APJ). Apelin-13, as the most bioactive affinity fragment of apelin, plays a role in energy metabolism, myocardial ischemia-reperfusion
Taotao Lin, Yujie Zhao, Shengyu Guo, Zhengru Wu, Wenwen Li, Rongcan Wu, Zhenyu Wang, Wenge Liu   +7 more
doaj   +1 more source

Hydrostatic pressure does not cause detectable changes to survival of human retinal ganglion [PDF]

, 2015
Purpose: Elevated intraocular pressure (IOP) is a major risk factor for glaucoma. One consequence of raised IOP is that ocular tissues are subjected to increased hydrostatic pressure (HP).
Amal Aldarwesh, Andrew Osborne, B Coudrillier, C Zhang, CF Burgoyne, CF Burgoyne, Claire Everitt, CR Ethier, David C. Broadway, G Morris, G Tezel, G Tezel, Glyn Chidlow, HA Quigley, IA Sigal, J Vandesompele, JC Downs, JC Dreixler, Jeremy D. Rhodes, Julie Sanderson, L Mester, LK Mao, M Inatani, M Kikuchi, MC Leske, MC Leske, N Niyadurupola, N Niyadurupola, NN Osborne, RM Sappington, RM Sappington, S Resnikoff, S Roth, V Resta, VT Ribas, Y Lei   +35 more
core   +2 more sources

HUWE1 E3 ligase promotes PINK1/PARKINindependent mitophagy by regulating AMBRA1 activation via IKKa [PDF]

, 2018
The selective removal of undesired or damaged mitochondria by autophagy, known as mitophagy, is crucial for cellular homoeostasis, and prevents tumour diffusion, neurodegeneration and ageing.
A Criollo, A Hamacher-Brady, A Hamacher-Brady, A Rita Di, A Rita Di, A Rozenknop, A Sali, A Sprenger, A Stolz, A Tanaka, AY Abramov, B Richter, C Margreitter, D Knight, DW Choi, EM Valente, F Strappazzon, F Strappazzon, F Strappazzon, F Strappazzon, G Ashrafi, G Xu, GA Khoury, GP Leboucher, H Sandoval, H Tomita, H Zhou, I Matic, I Novak, J Kitchen, JJ Lemasters, JL Parsons, JM Heo, K Sugawara, K Yamano, L Liu, LA Kane, M Campanella, M Karbowski, M Laforge, M Lazarou, M Pasi, M Pilli, M Tiberti, M Tiberti, MJ Abraham, MP Williamson, N Bakkar, N Shembade, NC Chan, P Bjelkmar, P Wild, Q Zhong, RK Dagda, S Inoue, S Piana, T Kitada, T Murakawa, T Tatsuta, TN Nguyen, V Cianfanelli, VV Rogov, VV Rogov, VV Rogov, W Zhang, Y Chen, Y Ichimura, Y Wei, Y Xue, Y Yuan, Y Zhu   +70 more
core   +4 more sources

Gp91phox (NOX2) in Activated Microglia Exacerbates Neuronal Damage Induced by Oxygen Glucose Deprivation and Hyperglycemia in an in Vitro Model

Cellular Physiology and Biochemistry, 2018
Background/Aims: Peri-operative cerebral ischemia reperfusion injury is one of the most serious peri-operative complications that can be aggravated in patients with diabetes.
Xianzhang Zeng, Hongliang Ren, Yana Zhu, Ruru Zhang, Xinxin Xue, Tao Tao, Hongjie Xi   +6 more
doaj   +1 more source