Results 91 to 100 of about 2,136,764 (318)

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Shale oil technical advisory committee, minutes of the twentieth regular meeting

, 2022
Includes charts.These minutes were recorded at the Technical Advisory Committee meetings and include agenda, budget, and technical reports about work performed at Anvil Points.A Technical Advisory Committee was formed by Socony Mobil, ESSO Research and ...

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Educación 5.0: Análisis de implicaciones para una formación integral

Ciencia y Educación
El presente estudio analiza las implicaciones de la Educación 5.0 para la formación integral, enmarcada en el contexto de las transformaciones industriales y tecnológicas, particularmente la Industria 5.0.
Haider Esteban Bautista Joaqui, José Oil Pineda Rondón   +1 more
doaj  

Impact of Elevated CO2 on Seed Quality of Soybean at the Fresh Edible and Mature Stages

Frontiers in Plant Science, 2018
Although the effect of elevated CO2 (eCO2) on soybean yield has been well documented, few studies have addressed seed quality, particularly at the fresh edible (R6) and mature stages (R8).
Yansheng Li, Zhenhua Yu, Jian Jin, Jian Jin, Qiuying Zhang, Guanghua Wang, Changkai Liu, Junjiang Wu, Cheng Wang, Xiaobing Liu   +9 more
doaj   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Agreement between Mobil Oil Corporation and Colorado School of Mines, Research Foundation on Mobil's mining program at Anvil Points

, 2022
This agreement is about the oil shale project utilizing the Anvil Points Facilities.The United States Bureau of Mines facility at Anvil Points, near Rifle, Colorado, was reactivated starting in May 1964 and was operated during 1965, 1966, and 1967.

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Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

FEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang, Mingqiang Deng, Dongmei He, Diqin Lai, Dongjun Liu, Dengyong Zhu, Zhenhua Zhang, Peng Tang, Chuanman Zhou, Menghui Yin, Xichen Bao   +10 more
wiley   +1 more source

Technical memorandum no. 66-5: preliminary cost study on underground mining of oil shale by the room and pillar method

, 2022
Includes charts. Unscanned drawing, contact the Library for more information.The United States Bureau of Mines facility at Anvil Points, near Rifle, Colorado, was reactivated starting in May 1964 and was operated during 1965, 1966, and 1967.

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Isolation and Characterization of Castor Seed Oil and Its Utilization Potential in the Production of Polyurethane Foam

Walailak Journal of Science and Technology, 2013
Firm polyurethane (PU) foams were prepared using Nigerian grown brown and white castor seed oil starting materials extracted at ambient temperature. Polyol with terminal primary hydroxyl groups synthesized from crude castor oil were reacted with aromatic
Aishat IMASUEN, Festus INEGBEDION, Christopher ERHABOR, Michae OSUIDE   +3 more
doaj   +1 more source

Future of Oil and Gas Trade of Kazakhstan in the European Union Context – Application of Time Series Analysis

Visegrad Journal on Bioeconomy and Sustainable Development, 2020
Energy is a fundamental factor in cooperation between Kazakhstan and the European Union; both sides strive for energy security but understand it differently.
Kabylda Alisher, Turčeková Natália, Čeryová Dominika, Belinska Stefaniia, Valentíni Filip   +4 more
doaj   +1 more source