Results 21 to 30 of about 1,622,798 (268)

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, Volume 20, Issue 6, Page 1453-1472, June 2026.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Shale oil technical advisory committee, minutes of the third meeting

open access: yes, 2022
Includes charts.These minutes were recorded at the Technical Advisory Committee meetings and include agenda, budget, and technical reports about work performed at Anvil Points.A Technical Advisory Committee was formed by Socony Mobil, ESSO Research and ...

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TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Mechanical model simulation - a valuable technique for oil shale research

open access: yes, 2022
Report no. 67.72 AP.This is the third in a series of seven final summary reports covering specific research programs performed under the auspices of the Initial Program at Anvil Points.The U.S.

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Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Shale oil technical advisory committee, minutes of the twelfth meeting

open access: yes, 2022
Includes charts.These minutes were recorded at the Technical Advisory Committee meetings and include agenda, budget, and technical reports about work performed at Anvil Points.A Technical Advisory Committee was formed by Socony Mobil, ESSO Research and ...

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Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Evaluation of the performance of rear dump trucks for oil shale mining and hauling

open access: yes, 2022
Technical memorandum no. 67-42.Includes drawings.These technical memoranda pertain to work performed at Anvil Points.The United States Bureau of Mines facility at Anvil Points, near Rifle, Colorado, was reactivated starting in May 1964 and was operated ...

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Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Shale oil technical advisory committee, minutes of the seventeenth meeting

open access: yes, 2022
Includes charts.Three unscanned drawings, contact the Library for more information.These minutes were recorded at the Technical Advisory Committee meetings and include agenda, budget, and technical reports about work performed at Anvil Points.A Technical

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