Results 51 to 60 of about 5,037,008 (338)
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Biochemical properties of new varieties of rape
100 rape varieties and hybrids of domestic and foreign selection that have been grown in the different soil-climatic zones of the country were evaluated.
О. І. Рудник-Іващенко +6 more
doaj +1 more source
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Quality characteristics of edible linseed oil [PDF]
In this review the quality properties of linseed oil for food uses are discussed as well as factors affecting this quality. Linseed oil has a favourable fatty acid composition with a high linolenic acid content.
Gates, Fred +3 more
core
Mass Exchange Dynamics of Surface and Subsurface Oil in Shallow-Water Transport [PDF]
We formulate a model for the mass exchange between oil at and below the sea surface. This is a particularly important aspect of modeling oil spills.
Moghimi, Saeed +3 more
core +3 more sources
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
According to the International Energy Agency, Brazil plays a central role in meeting the world’s oil needs through to 2035, accounting for one-third of the net growth in global supply.
Guilherme Baptista Schwartsmann
doaj +1 more source
China’s energy transition: preliminary results and challenges for the future
The article is devoted to the study of China’s energy transition policy and the prospects for its implementation. As the world’s second largest economy, the People’s Republic of China has become an important part of the global energy market in recent ...
L. Xialan
doaj +1 more source
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad +35 more
wiley +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source

