Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Application of the mercury porosimetry method in the analysis of sorption materials
Objectives. This study aims to establish the available porosity of a sorbent based on carbonized rice husk and investigate its sorption properties for oil and oil products.Methods.
R. K. Kostoev +6 more
doaj +1 more source
How oil prices impact the labor market: empirical evidence from Alaska [PDF]
Thesis (M.S.) University of Alaska Fairbanks, 2016The present paper uses a linear autoregressive distributed lag (ARDL) approach in order to test for symmetric effects of oil price changes on employment in the oil-industry and employment in non-oil ...
Bocklet, Johanna
core
Conservation Value and Permeability of Neotropical Oil Palm Landscapes for Orchid Bees [PDF]
The proliferation of oil palm plantations has led to dramatic changes in tropical landscapes across the globe. However, relatively little is known about the effects of oil palm expansion on biodiversity, especially in key ecosystem-service providing ...
Gilbert, Lawrence +3 more
core +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
The remonal effect of hydrogenated shortening on serum levels of triglycerids,total cholesterol and HDL-cholesterol in normal subjects [PDF]
In Iran,the hydrogenated vegetable oil have content of frans fatty acids and high per capita consumption.this study was aimed to evaliate the effects of substitution of hydrogenated oil by sunflower liquid oil on plasma levels of LDL,HDL, total ...
GH.R Bahrami, H Rahi
doaj
The ever-increasing complexity of semiconductor devices requires innovative three-dimensional materials characterization techniques for confined volumes.
Céline Noël +5 more
doaj +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Oil quality in diesel engines with on line oil cleaning using a heated lubricating oil recycler [PDF]
A method of cleaning the oil on line was investigatedusing a bypass fine particulate filter followed by an infra red heater to remove water and light diesel fractions in the oil.
Andrews, Gordon +6 more
core
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source

