Results 41 to 50 of about 5,975,702 (318)
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Evaluation of oil-water separation techniques on retort no. 3
, 2022 Technical memorandum no. 67-21.Includes charts.These technical memoranda pertain to work performed at Anvil Points.The United States Bureau of Mines facility at Anvil Points, near Rifle, Colorado, was reactivated starting in May 1964 and was operated ...
core
You-qi chuyun, 2023 Waxy crude oil stored in the tank for a long time will form tank bottom sediment. The settling of tank bottom deposits in oil flow during the pipeline transportation of waxy crude oil will reduce the pipeline transportation capacity, and even block the ...
YANG Ming +7 more
doaj +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Shale oil technical advisory committee, minutes of the fifth meeting
, 2022 Includes charts.These minutes were recorded at the Technical Advisory Committee meetings and include agenda, budget, and technical reports about work performed at Anvil Points.A Technical Advisory Committee was formed by Socony Mobil, ESSO Research and ...
core
You-qi chuyunObjectiveDriven by the accelerating global transition toward a diversified, low-carbon energy structure, the need for intensive pipeline utilization continues to rise.
Yongtu LIANG +5 more
doaj +1 more source
Molecular Oncology, EarlyView.We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee +3 more
wiley +1 more source
Shale oil technical advisory committee, minutes of the fourteenth meeting
, 2022 Includes charts.These minutes were recorded at the Technical Advisory Committee meetings and include agenda, budget, and technical reports about work performed at Anvil Points.A Technical Advisory Committee was formed by Socony Mobil, ESSO Research and ...
core
Improved analytical method for strain of submarine pipeline under faulting
You-qi chuyun, 2020 Active fault is a major geological hazard threat to submarine pipelines, which may subject to excessive axial deformation and fail from the faulting.
Xiaoben LIU +4 more
doaj +1 more source
Molecular Oncology, EarlyView.The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim +17 more
wiley +1 more source