Results 51 to 60 of about 364,533 (266)

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

open access: yesFEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose   +9 more
wiley   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

open access: yesFEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya   +2 more
wiley   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

open access: yesFEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana   +5 more
wiley   +1 more source

Simulation on Line C of the China–Central Asia Gas Pipeline based on SPS software

open access: yesYou-qi chuyun, 2020
The Line C of the China–Central Asia Gas Pipeline is a typical gas pipeline characterized by high transmission pressure, large flow, long pipeline span, numerous gas stations and complicated transportation technology.
Yansong LI   +5 more
doaj   +1 more source

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

open access: yesFEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito   +7 more
wiley   +1 more source

De novo synthesis of short‐chain aldehydes and hydrocarbons secreted by the brown marmorated stink bug Halyomorpha halys

open access: yesFEBS Open Bio, EarlyView.
The brown marmorated stink bug, Halyomorpha halys, mainly secretes 4‐oxo‐(E)‐2‐hexenal, (E)‐2‐decenal, dodecane and tridecane, a mixture representative of that released by many heteropterans. We demonstrated that H. halys can synthesise these secretory components de novo using dietary glucose.
Haruna Fujimori, Koji Noge
wiley   +1 more source

A rapid calculation method for dynamic linepack of natural gas by coupling data and mechanism models

open access: yesYou-qi chuyun
ObjectivePipelines are essential for the long-distance natural gas transportation and play a crucial role in national energy security. The linepack, as a comprehensive operational parameter for natural gas pipeline networks, embodies both safety and ...
Xiong YIN   +7 more
doaj   +1 more source

An MILP Method for Design of Distributed Energy Resource System Considering Stochastic Energy Supply and Demand

open access: yesEnergies, 2017
A distributed energy resource (DER) system, which can be defined as a medium or small energy conversion and utilization system with various functions for meeting multiple targets, is directly oriented towards users and achieves on-site production and ...
Zhigang Duan   +6 more
doaj   +1 more source

Threonine 348 regulates the subcellular localization of PTEN

open access: yesFEBS Open Bio, EarlyView.
Thr348 in the C2 domain is a key contributor to PTEN subcellular localization. The PTEN350 fragment and PTENA4 accumulated in the nucleus, whereas PTENK13R,A4 predominantly localized to the plasma membrane. In contrast, substitution of Thr348 with Asp (T348D) disrupted these characteristic localization patterns, resulting in predominant cytoplasmic ...
Takashi Kato, Suzu Tanaka, Miyu Ohashi
wiley   +1 more source

Research of Oil Product Secondary Distribution Optimization Based on Collaborative Distribution

open access: yesProcedia Computer Science, 2015
AbstractDuring peak seasons, the petrol company's oil supply capacity is insufficient, therefore, with limited trucks, adjusting the distribution quantity of petrol station and formulating an effective distribution route can minimize the total cost and maximize the vehicle utilization. In this paper we observe the extension of the multi-depot half open
Xuping Wang, Hongxin Zhan, Jun Zhang
openaire   +1 more source

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