Results 131 to 140 of about 16,816 (218)

Obstetrics and gynecology devices designed for low‐ and middle‐income countries: A narrative review

International Journal of Gynecology &Obstetrics, Volume 169, Issue 1, Page 71-80, April 2025.
Abstract There are many barriers contributing to poor health outcomes for women in low‐ and middle‐income countries (LMICs), one of which is the lack of necessary medical devices. Presently, the development of various kinds of devices intended to improve women's health outcomes specifically in LMICs remains underrepresented in the literature; therefore,
Dhanalakshmi Thiyagarajan, Enaam A. Adanu, K. Rivet Amico   +2 more
wiley   +1 more source

Decidual macrophage‐mediated ferroptosis in trophoblasts leads to recurrent spontaneous abortion

iMeta, EarlyView.
Decidual macrophages from recurrent spontaneous abortion (RSA) patients promote trophoblast ferroptosis and impair trophoblast cell function. Mechanistically, the CXCL2/NF‐κB/HMOX1 axis mediates this effect. Conversely, trophoblasts co‐cultured with RSA decidual macrophages induce pro‐inflammatory macrophage polarization through IL‐6/JAK2/STAT3 ...
Xin Chen, Xueqin Ma, Pengcheng Pang, Heng Zhou, Ruohan Li, Yan He, Yan Zhang, Jing Yang, Qianlin Song, Qingsong Ye   +9 more
wiley   +1 more source

A survey of regulatory recommendations for waivers of <i>in vivo</i> bioequivalence studies of generic products for certain dosage forms by participating regulators and organisations of the International Pharmaceutical Regulators Programme. Part 2. [PDF]

J Pharm Pharm Sci
García-Arieta A, Tam A, Tiseyra F, Fernandes EAF, Soares KCC, Pereira RS, Potthast H, Mettke K, Chang YW, Hsu LF, Su YL, Martínez ZR, Divinsky M, Blake K, Braddy AC, Rodrigues C, Toh T, Aurela EG, González LCA, Jones B, Kim SH, Ahn C, Yun E, Kuribayashi R, Shimojo K, Kasuga M, Makino J, Raffel J, van Oudtshoorn J, Tabane P, Alzenaidy B, AlHarbi M, Alharf A, BinAjlan A, Walther C, Roost MS, Crane C, Lee K.   +37 more
europepmc   +1 more source

Complement C3 mediates adolescent social isolation‐induced hippocampal synaptic deficits and sex‐specific emotional dysfunction

Interdisciplinary Medicine, EarlyView.
Adolescent social isolation disrupts hippocampal function and exacerbates emotional symptoms, with sex‐specific patterns, as shown by human studies. In mice, social isolation decreased hippocampal synaptic density and calcium signaling, upregulated complement proteins, and activated complement‐mediated microglial synaptic phagocytosis.
Yuwan Qi, Siying Weng, Qiao Yin, Mengqi Li, Liang Shen, Enyou Qiao, Lu Gao, Yihan Wang, Yuxuan Li, Weifeng Luo, Qilin Zhang, Jing Wang, Jianfeng Feng, Qifei Cong   +13 more
wiley   +1 more source

Evidence- and consensus-based guideline on lichen sclerosus. [PDF]

J Dtsch Dermatol Ges
Kirtschig G, Woelber L, Günthert A, Becker K, Ciresa-König A, Fischer B, Fricke-Otto S, Günther C, Hirchenhain C, Köllmann NH, Kreuter A, Malisiewicz B, Neis F, Mon O'Dey D, Ott H, Promm M, Renner R, Schardt AR, Schweizer I, Stein R, Ter-Nedden J, Trutnovsky G, Wand A, Weyandt G, Werner RN, Kinberger M.   +25 more
europepmc   +1 more source

Effect of Zinc Oxide Nanoparticles From Infant Formula Milk Powder on Colon Cells In Vitro

Journal of Applied Toxicology, EarlyView.
ABSTRACT Zinc is an essential trace element that participates in numerous metabolic processes; however, excessive exposure may interfere with the absorption of other metals, such as copper. In recent years, nanotechnology has experienced rapid growth, and zinc oxide nanoparticles (ZnO NPs) have garnered significant attention due to their versatile ...
Gloria Salinas‐Lucero, Karla Juarez‐Moreno, Rafael Vazquez‐Duhalt   +2 more
wiley   +1 more source

Phytochemistry and Pharmacological Properties of Medicinal Plants. [PDF]

Plants (Basel)
Maroyi A.
europepmc   +1 more source

Nanostructured lipid carriers and natural deep eutectic solvents: a highly advantageous combination for the encapsulation of curcumin

Journal of Chemical Technology &Biotechnology, EarlyView.
Abstract BACKGROUND Curcumin is a naturally derived polyphenol known for its potent biological properties. Its therapeutic potential, however, is hindered by low bioavailability. Nanostructured lipid carriers (NLCs) have emerged as advanced delivery systems to overcome such limitations. Natural deep eutectic solvents (NADESs) have garnered attention as
Kyriaki Safari, Ioanna Pitterou, Marianthi Miliaronikolaki, Nikolaos Paraskevopoulos, Andromachi Tzani, Anastasia Detsi   +5 more
wiley   +1 more source

Rheological Assessment for Determining Form Stability of Wound Dressings. [PDF]

Int Wound J
Gefen A, Weihs D, Fremau A, Eynde YVD, Torfs E.   +4 more
europepmc   +1 more source

Noncanonical Nucleotides in the Genome Around the Maternal‐Zygotic Transition

Journal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.
In this paper, Kazzazi et al. provide a comprehensive review of the dynamics of nonconventional nucleotides in the genome during early developmental stages, hypothesizing a potential role for these nucleotides in the activation of the zygotic genome. ABSTRACT From the very moment of fertilization and throughout development, the cells of animal embryos ...
Latifa Kazzazy, Dávid Mező, Kinga K. Nagy, Viktória Perey‐Simon, Judit Tóth, Angéla Békési, Beáta Vértessy, Máté Varga   +7 more
wiley   +1 more source