Results 131 to 140 of about 21,271 (292)

Targeted Mechanogenetics to Modulate Specific Deep Neural Circuits

Advanced Science, EarlyView.
This study introduces mechanogenetics, a nanobubble‐enhanced sonogenetic strategy for selective modulation of feeding‐related neural circuits in the mouse lateral hypothalamus. Mechanogenetic stimulation modulates feeding behavior through glutamatergic projections from the lateral hypothalamus to the ventral tegmental area, highlighting its potential ...
Xuandi Hou, Jianing Jing, Zhuohan Shi, Lei Sun   +3 more
wiley   +1 more source

Exploration of the Wound Healing Activity of Ethanol Extract-Based Ointment from Curry Leaves on the Wound Healing Process

Journal of Food and Pharmaceutical Sciences
Indonesian society widely utilizes traditional medicinal plants, including curry leaves (Murraya koenigii L.), which contain alkaloids, tannins, flavonoids, saponins, steroids, and triterpenoids known to possess antioxidant and anti-inflammatory ...
Andilala Andilala, Juliana Sion Sihombing   +1 more
doaj   +1 more source

Wound healing properties of ointments with different copper nanoparticles containing

, 2011
Wound healing activity of ointments on the methylcellulose base containing various concentrations of copper nanoparticles is presented. It was found that the optimal effect on healing process has the ointment containing 0,002% of copper ...
M J Mbasha, I P Olkhovskaya, A N Ganzhigaeva, A A Rakhmetova, O A Bogoslovskaya, N N Glushchenko   +5 more
core  

Modulation of Presynaptic Inhibitory Retinal Circuits for Retinal Ganglion Cell Neuroprotection in Glaucoma

Advanced Science, EarlyView.
Ocular hypertension induces early hyperactivity in inner retinal inhibitory circuitry before substantial retinal ganglion cell loss. Sustained pharmacological inhibition of GABAergic/glycinergic neurotransmission and Vgat‐targeted Lin28 expression suppress this hyperactivity and improve RGC survival without reducing intraocular pressure. These findings
Eunji Hong, Chen Lin, Wenjie Long, Ian Kim, Mengwen Xiong, Zuer Wu, Siyuan Rao, Qianbin Wang   +7 more
wiley   +1 more source

DEVELOPMENT OF PRODUCING SOFT MEDICINAL FORMS CONTAINING SOLID DISPERSION

Разработка и регистрация лекарственных средств, 2019
The technology of obtaining samples of ointments of nifedipine on the emulsion and hydrophilic bases using the method of solid dispersions is developed. The quality of the obtained soft medicinal forms was evaluated.
V. V. Grih, I. I. Krasnyuk (jr.), O. I. Stepanova, A. V. Belyatskaya, I. I. Krasnyuk, V. V. Tarasov, D. A. Kozin, E. Nesterenko   +7 more
doaj  

THE ABSORPTION OF OINTMENTS [PDF]

BMJ, 1908
openaire   +2 more sources

β‐Adducin Restrains PLA2G4A‐Dependent Lysosomal Membrane Permeabilization and Neuronal Death in Ischemic Stroke

Advanced Science, EarlyView.
This study identifies β‐adducin as a regulator of lysosomal integrity in ischemic neurons. Ischemia‐associated FTO loss increases m6A modification and destabilizes Add2 mRNA, reducing β‐adducin expression and promoting PLA2G4A accumulation at lysosomes.
Hui‐qin Li, Pin‐yi Liu, Dan Wu, Fei‐yu Ma, Yi Bai, Sheng‐nan Xia, Hai‐yan Yang, Xin‐yu Bao, Yun Xu, Xiang Cao   +9 more
wiley   +1 more source

European guidelines from the EHTG and ESCP for Lynch syndrome: an updated third edition of the Mallorca guidelines based on gene and gender

BJS (British Journal of Surgery), EarlyView., 2020
Recommendations for clinical and molecular identification of LS, surgical and endoscopic management of LS‐associated colorectal cancer and preventive measures for cancer were produced. The emphasis was on surgical and gastroenterological aspects of the cancer spectrum.
T. T. Seppälä, A. Latchford, I. Negoi, A. Sampaio Soares, R. Jimenez‐Rodriguez, L. Sánchez‐Guillén, D. G. Evans, N. Ryan, E. J. Crosbie, M. Dominguez‐Valentin, J. Burn, M. Kloor, M. von Knebel Doeberitz, F. J. B. van Duijnhoven, P. Quirke, J. R. Sampson, P. Møller, G. Möslein, on behalf of the European Hereditary Tumour Group (EHTG) and European Society of Coloproctology (ESCP)   +18 more
wiley   +1 more source

Low‐Density Lipoprotein Receptor‐Targeted Biomimetic Nanoplatform Suppresses Glioblastoma Stemness and Remodels Antitumor Immunity via Dual Metabolic Disruption

Advanced Science, EarlyView.
A low‐density lipoprotein receptor‐oriented biomimetic nanoplatform couples brain‐tumor delivery with a mechanistically matched regorafenib‐erythrodiol combination. Concurrent disruption of autophagic nutrient salvage and cholesterol homeostasis collapses bioenergetic and signaling support, suppresses glioblastoma stemness, and promotes immunogenic ...
Yining Jiang, Wenzhuo Yang, Wenting Cheng, Jing Zuo, Lin Pan, Sheng Zhong, Ren Geng, Yao Zhao, Zijian Chen, Canhua Huang, Yang Bai, Liyan Zhao, Yunqian Li   +12 more
wiley   +1 more source

A study of the structural-mechanical properties of ointment bases and ointments on triethanolaminobethonite

, 1973
The structural-mechanical properties have been studied of a new emulsion water-washable ointment base (WWOB) on triethanolaminobenthonite. The prepared on this base ointments with levomycetin and boric acid gave a positive result in 82% of patients ...
Salo, D. P., Третинник, В. Ю., Лехан, А. С., Круглицкий, М. М., Сало, Д. П., Lekhan, A. S., Tretinnik, V. Yu., Kruglitsky, M. M.   +7 more
core