Results 161 to 170 of about 14,228 (214)
Degradation of okadaic acid in seawater by UV/TiO2 photocatalysis - Proof of concept.
Sci Total Environ, 2020 Camacho-Muñoz D, Lawton LA, Edwards C.
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Comparative toxicity of dinophysistoxin-1 and okadaic acid in mice. [PDF]
J Vet Med Sci, 2018 Suzuki H, Okada Y.
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Binding competition of okadaic acid derivatives to anti-okadaic acid antibody
Toxicon, 1991The serologic activities of structurally related okadaic acid derivatives have been determined. Binding of [3H]okadaic acid to rabbit anti-okadaic acid is inhibited with equal effectiveness by okadaic acid, dinophysistoxin-1, acanthifolicin, okadaic acid tetramethyl ether, and okadaic acid spiroketal II.
J, Yatsunami +6 more
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Influence of amino acids on okadaic acid production
Toxicon, 2001Okadaic acid (OA) (1)) was the first example of a group of polyether toxins known to be produced by marine microalgae, which are responsible for the natural phenomena known as Diarrhetic Shellfish Poisoning (DSP) red tides. It is also a highly selective inhibitor of protein phosphatases type 1 (PP1) and 2A (PP2A), as well as being a potent tumour ...
M L, Souto +4 more
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Induction of actin cytoskeleton rearrangement by methyl okadaate – comparison with okadaic acid
The FEBS Journal, 2008Methyl okadaate is a derivative of the lipophilic polyether okadaic acid (OA), a well‐known inducer of apoptosis. OA inhibits Ser/Thr protein phosphatases (PPs), among them types 1 and 2A (PP1 and PP2A), whereas methyl okadaate lacks PP1/PP2A inhibitory activityin vitro.
Natalia, Vilariño +6 more
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Complexation of okadaic acid : A preliminary study
Bioorganic & Medicinal Chemistry Letters, 1998A complexation study was carried out with okadaic acid (OA) and the univalent metal ions Li+, Na+ and K+, and the divalent metal ions Ca2+ and Mg2+. K+ binding was observed identical with a complex obtained from the natural source (OAC). The pharmacological trials demonstrated that this cation has a very important influence on the pharmacological ...
M, Norte +5 more
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Effects of Okadaic Acid on Rat Colon
Digestive Diseases and Sciences, 1998Effects of okadaic acid (OA) on mucosal damage were examined in rat colon. OA was sprinkled on rat colon mucosa under observation with an electronic-endoscopic system, and OA was also applied to the in vivo microscopic field. The OA-induced changes in transepithelial conductance (Gt) were measured by the Ussing voltage clamp technique.
M, Hosokawa +7 more
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Effect of Okadaic Acid on Glucose Regulation
Mini-Reviews in Medicinal Chemistry, 2005Okadaic acid is the main toxin responsible for the natural phenomena known as diarrheic shellfish poisoning (DSP). This toxin is a tumor promoter C38 polyether fatty acid that contains acidic and hydrophobic moieties and is cyclic. Okadaic acid is a potent inhibitor of important classes of protein serine/threonine phosphatases such as protein ...
M C, Louzao, M R, Vieytes, L M, Botana
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Toxicon, 2010
The subcellular distribution of okadaic acid, the main diarrhetic shellfish poisoning (DSP) toxin, in the cells of the digestive gland of the mussel Mytilus galloprovincialis was studied. By means of differential centrifugation, ultrafiltration and extraction with methanol, it was found that most okadaic acid was stored in the cytosol.
Araceli Escudeiro Rossignoli +1 more
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The subcellular distribution of okadaic acid, the main diarrhetic shellfish poisoning (DSP) toxin, in the cells of the digestive gland of the mussel Mytilus galloprovincialis was studied. By means of differential centrifugation, ultrafiltration and extraction with methanol, it was found that most okadaic acid was stored in the cytosol.
Araceli Escudeiro Rossignoli +1 more
exaly +3 more sources