Results 1 to 10 of about 27,561 (125)

Olanzapine

open access: yesReactions Weekly, 2006
europepmc   +3 more sources

Olanzapine-Induced Activation of Hypothalamic Astrocytes and Toll-Like Receptor-4 Signaling via Endoplasmic Reticulum Stress Were Related to Olanzapine-Induced Weight Gain

open access: yesFrontiers in Neuroscience, 2021
The antipsychotic drug olanzapine is associated with serious obesity side effects. Hypothalamic astrocytes and associated toll-like receptor-4 (TLR4) signaling play an essential role in obesity pathogenesis.
Meng He   +9 more
doaj   +1 more source

A case report and literature review of olanzapine-associated hyperglycemia with previous history of gestational diabetes [PDF]

open access: yesMental Health Clinician, 2022
Background: Olanzapine (Zyprexa) package labeling includes a warning for hyperglycemia, stating physicians should consider the risks and benefits when prescribing olanzapine to patients with an established diagnosis of diabetes mellitus or having ...
Jennifer N. Alastanos, PharmD, BCPP, BCPS   +3 more
doaj   +1 more source

A meta-analysis comparing short-term weight and cardiometabolic changes between olanzapine/samidorphan and olanzapine

open access: yesScientific Reports, 2021
This study compared weight and cardiometabolic changes after short-term treatment of olanzapine/samidorphan and olanzapine. Eligible criteria for an included trial were ≤ 24 weeks, randomized controlled trials (RCTs) that compared olanzapine/samidorphan ...
Manit Srisurapanont   +4 more
doaj   +1 more source

Alterations in sorting and secretion of hepatic apoA5 induce hypertriglyceridemia due to short-term use of olanzapine

open access: yesFrontiers in Pharmacology, 2022
Long-term use of olanzapine, an antipsychotic drug, induces hypertriglyceridemia, resulting in a higher risk of cardiovascular disease. However, the effects and underlying mechanisms of short-term use of olanzapine on circulating triglyceride levels ...
Piao-Piao Huang   +23 more
doaj   +1 more source

Olanzapine-induced neutropenia [PDF]

open access: yesMental Illness, 2015
Olanzapine-induced neutropenia is a rare adverse effect that is currently poorly described in literature. Although neutropenia is a known adverse effect of clozapine, it has been associated with the use of other antipsychotic medications like olanzapine. This case report describes and reviews a case of olanza-pine-induced neutropenia in a schizophrenic
Kirti Malhotra   +4 more
openaire   +3 more sources

CYP1A2 expression rather than genotype is associated with olanzapine concentration in psychiatric patients

open access: yesScientific Reports, 2023
Olanzapine is a commonly prescribed atypical antipsychotic agent for treatment of patients with schizophrenia and bipolar disorders. Previous in vitro studies using human liver microsomes identified CYP1A2 and CYP2D6 enzymes being responsible for CYP ...
Ferenc Fekete   +9 more
doaj   +1 more source

The Balance Between the Effectiveness and Safety for Chemotherapy-Induced Nausea and Vomiting of Different Doses of Olanzapine (10 mg Versus 5 mg): A Systematic Review and Meta-Analysis

open access: yesFrontiers in Oncology, 2021
IntroductionThe aim of this study is to rigorously review the efficacy and safety of olanzapine in chemotherapy-induced nausea and vomiting (CINV) settings including (1) at 5- and 10-mg doses, and (2) the setting of highly emetogenic chemotherapy (HEC ...
Dong-Yang Wang   +3 more
doaj   +1 more source

Longitudinal Gut Microbiota Dysbiosis Underlies Olanzapine-Induced Weight Gain

open access: yesMicrobiology Spectrum, 2023
Olanzapine is one of the most effective medicines available for stabilizing schizophrenia spectrum disorders. However, it has been reported to show the greatest propensity for inducing body weight gain and producing metabolic side effects, which cause a ...
Li Qian   +10 more
doaj   +1 more source

Olanzapine-induced hiccups: a case report

open access: yesSichuan jingshen weisheng, 2021
The case report aims to raise the concern of clinicians about hiccups as an adverse reaction in olanzapine treatment. A 47-year-old male patient with epileptic mental disorder appeared symptoms of persistent hiccups on the fourth day of treatment with ...
Sun Zhenxiao, Xu Chunmei, Zhao Lin
doaj   +1 more source

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