Results 1 to 10 of about 84,234 (301)

Long-term functional improvements in the 2-year treatment of schizophrenia outpatients with olanzapine long-acting injection [PDF]

Neuropsychiatric Disease and Treatment, 2014
Haya Ascher-Svanum,1 Diego Novick,2,3 Josep Maria Haro,4 Jordan Bertsch,4 David McDonnell,1 Holland Detke11Eli Lilly and Company, Indianapolis, IN, USA; 2Eli Lilly and Company, Windlesham, Surrey, UK; 3Departament de Psiquiatria, Universitat Autonoma de ...
Ascher-Svanum H, Novick D, Haro JM, Bertsch J, McDonnell D, Detke H   +5 more
doaj   +4 more sources

Olanzapine for the Prevention of Chemotherapy-Induced Nausea and Vomiting [PDF]

New England Journal of Medicine, 2016
BACKGROUND We examined the efficacy of olanzapine for the prevention of nausea and vomiting in patients receiving highly emetogenic chemotherapy.
Bajaj, Madhuri, Biggs, David, Dietrich, Leah, Lafky, Jacqueline M., Liu, Heshan, Loprinzi, Charles L., Navari, Rudolph M., Powell, Steven F., Qin, Rui, Ruddy, Kathryn J.   +9 more
core   +2 more sources

Olanzapine for chemotherapy-induced nausea and vomiting: systematic review and meta-analysis

Pharmacy Practice, 2017
Background: Chemotherapy induced nausea and vomiting (CINV) remains the most distressing event in patients receiving highly emetogenic chemotherapy (HEC) or moderately emetogenic chemotherapy (MEC).
Chelkeba L, Gidey K, Mamo A, Yohannes B, Matso T, Melaku T.   +5 more
doaj   +2 more sources

Long-term administration of olanzapine induces adiposity and increases hepatic fatty acid desaturation protein in female C57BL/6J mice [PDF]

Iranian Journal of Basic Medical Sciences, 2018
Objective(s): Weight gain and metabolic disturbances such as dyslipidemia, are frequent side effects of second-generation antipsychotics, including olanzapine. This study examined the metabolic effects of chronic olanzapine exposure.
Po-Hsun Hou, Geng-Ruei Chang, Chin-Pin Chen, Yen-Ling Lin, I-Shuan Chao, Ting-Ting Shen, Frank Mao   +6 more
doaj   +2 more sources

Olanzapine

Reactions Weekly, 2006
europepmc   +3 more sources

Olanzapine-induced lipid disturbances: A potential mechanism through the gut microbiota-brain axis

Frontiers in Pharmacology, 2022
Objective: Long-term use of olanzapine can induce various side effects such as lipid metabolic disorders, but the mechanism remains to be elucidated. The gut microbiota-brain axis plays an important role in lipid metabolism, and may be related to the ...
Zhenyu Zhu, Yuxiu Gu, Cuirong Zeng, Man Yang, Hao Yu, Hui Chen, Bi-kui Zhang, H. Cai   +7 more
semanticscholar   +1 more source

A meta-analysis comparing short-term weight and cardiometabolic changes between olanzapine/samidorphan and olanzapine

Scientific Reports, 2021
This study compared weight and cardiometabolic changes after short-term treatment of olanzapine/samidorphan and olanzapine. Eligible criteria for an included trial were ≤ 24 weeks, randomized controlled trials (RCTs) that compared olanzapine/samidorphan ...
Manit Srisurapanont, Sirijit Suttajit, Surinporn Likhitsathian, Benchalak Maneeton, Narong Maneeton   +4 more
doaj   +1 more source

Olanzapine-Induced Activation of Hypothalamic Astrocytes and Toll-Like Receptor-4 Signaling via Endoplasmic Reticulum Stress Were Related to Olanzapine-Induced Weight Gain

Frontiers in Neuroscience, 2021
The antipsychotic drug olanzapine is associated with serious obesity side effects. Hypothalamic astrocytes and associated toll-like receptor-4 (TLR4) signaling play an essential role in obesity pathogenesis.
Meng He, Kun Qian, Ying Zhang, Xu-Feng Huang, Chao Deng, Baohua Zhang, Guanbin Gao, Jing Li, Hao Xie, Taolei Sun   +9 more
doaj   +1 more source

Alterations in sorting and secretion of hepatic apoA5 induce hypertriglyceridemia due to short-term use of olanzapine

Frontiers in Pharmacology, 2022
Long-term use of olanzapine, an antipsychotic drug, induces hypertriglyceridemia, resulting in a higher risk of cardiovascular disease. However, the effects and underlying mechanisms of short-term use of olanzapine on circulating triglyceride levels ...
Piao-Piao Huang, Piao-Piao Huang, Wen-Qiang Zhu, Wen-Qiang Zhu, Jing-Mei Xiao, Yi-Qi Zhang, Rong Li, Yang Yang, Yang Yang, Li Shen, Li Shen, Fei Luo, Fei Luo, Fei Luo, Wen Dai, Wen Dai, Wen Dai, Ping-An Lian, Ping-An Lian, Ya-Xin Tang, Ya-Xin Tang, Juan-Li Ran, Xian-Sheng Huang, Xian-Sheng Huang   +23 more
doaj   +1 more source

A case report and literature review of olanzapine-associated hyperglycemia with previous history of gestational diabetes [PDF]

Mental Health Clinician, 2022
Background: Olanzapine (Zyprexa) package labeling includes a warning for hyperglycemia, stating physicians should consider the risks and benefits when prescribing olanzapine to patients with an established diagnosis of diabetes mellitus or having ...
Jennifer N. Alastanos, PharmD, BCPP, BCPS, Devika Suri, PharmD, Hayato DeLellis, PharmD, Andrea Mapugay, PharmD   +3 more
doaj   +1 more source