Results 161 to 170 of about 84,234 (301)

A Multicentre, 4‐Year Mirror‐Image Study Comparing the Effectiveness of Long‐Acting Injectable Antipsychotics in the Treatment of Bipolar Disorder: Results From the LAICO Study

open access: yesBipolar Disorders, Volume 28, Issue 1, February 2026.
ABSTRACT Background This was a 4‐year mirror‐image study of adult patients diagnosed with bipolar disorder (BD) assessing the effects on treatment continuation and hospitalisation between aripiprazole 1‐month (A1M), risperidone‐LAI (R‐LAI) and the monthly and 3‐monthly formulations of paliperidone palmitate (PP1M, PP3M).
Juan Antonio García‐Carmona   +5 more
wiley   +1 more source

Metabolic Syndrome Screening in Seriously Mentally Ill Patients: A Quality Improvement Project [PDF]

open access: yes, 2016
A Project Submitted in Partial Fulfillment of the Requirements for the Degree of MASTER OF SCIENCE in Nursing ScienceSeriously mentally ill patients who are taking second-generation antipsychotics have a high risk of metabolic complications ...
Moreno, Annabel
core  

Efficacy of a Transdiagnostic Sleep and Circadian Intervention for Outpatients With Sleep Problems and Depression, Attention Deficit Disorder, or Bipolar Disorder: A Randomised Controlled Trial

open access: yesJournal of Sleep Research, Volume 35, Issue 1, February 2026.
ABSTRACT This study aimed to investigate the efficacy of a Danish adaption of a transdiagnostic sleep and circadian intervention, combining cognitive behavioural therapy for insomnia with chronotherapy. A randomised controlled trial enrolling 88 outpatients with depression, attention deficit disorder, or bipolar disorder suffering from insomnia or ...
Mette Kragh   +5 more
wiley   +1 more source

The CCL11‐CCR3 Axis Regulates the Aggravation of Neuroinflammation in Astrocytic Necroptosis After Cerebral Ischemia

open access: yesThe FASEB Journal, Volume 40, Issue 1, 15 January 2026.
Schematic diagram of the triggering mechanism of necroptosis after cerebral ischemia. First, CCL11 targetedly binds to CCR3 on the surface of astrocytes and upregulates the expression of CCR3. After CCR3 activation, it triggers the transcriptional activation of necroptosis.
Han Yin   +10 more
wiley   +1 more source

Bioanalytical method development and validation for the simultaneous estimation of Olanzapine and Samidorphan in rabbit plasma by using HPLC–MS/MS and application to pharmacokinetic study

open access: yesFuture Journal of Pharmaceutical Sciences
Background Samidorphan is an opioid antagonist while Olanzapine is an effective medication for schizophrenia and bipolar disorder. A unique and accurate MS/HPLC approach due to simultaneous measurement of Olanzapine and Samidorphan is, therefore, more ...
Rambabu Kantipudi   +1 more
doaj   +1 more source

Initial dosage optimization of olanzapine in patients with bipolar disorder based on model-informed precision dosing: a study from the real world

open access: yesFrontiers in Pharmacology
ObjectivesOlanzapine is used for treating bipolar disorder (BPD); however, the optimal initial dosing regimen is unclear. The present study aimed to investigate the optimal olanzapine initial dosage in patients with BPD via model-informed precision ...
Xiao Chen   +7 more
doaj   +1 more source

Cost-Offsets of New Medications for Treatment of Schizophrenia [PDF]

open access: yes
Broad claims are frequently made that new medications will offset all or part of their costs by reducing other areas of Medicaid spending. In this paper we examine the net impact on spending for new drugs used to treat schizophrenia.
Richard G. Frank   +2 more
core  

Medicaid spending burden among beneficiaries with treatment-resistant depression. [PDF]

open access: yes, 2019
AIM: To evaluate Medicaid spending and healthcare resource utilization (HRU) in treatment-resistant depression (TRD). MATERIALS & METHODS: TRD beneficiaries were identified from Medicaid claims databases (January 2010-March 2017) and matched 1:1 with ...
Greenberg, Paul E.   +7 more
core   +1 more source

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