Results 41 to 50 of about 84,234 (301)

Teratogenicity with Olanzapine

open access: yesIndian Journal of Psychological Medicine, 2014
Olanzapine, a 2(nd) generation antipsychotic, is in use in the clinical practice for nearly a decade and a half now. It is classified as a category C drug with very few reports of its toxic effects on the fetus. In general, the risk benefit analysis warrants its use in pregnancy.
Sathya Prakash, Rakesh Kumar Chadda
openaire   +4 more sources

An in vivo biosensor for neurotransmitter release and in situ receptor activity. [PDF]

open access: yes, 2010
Tools from molecular biology, combined with in vivo optical imaging techniques, provide new mechanisms for noninvasively observing brain processes. Current approaches primarily probe cell-based variables, such as cytosolic calcium or membrane potential ...
Griesbeck, Oliver   +6 more
core   +2 more sources

N-acetylcysteine prevents olanzapine-induced oxidative stress in mHypoA-59 hypothalamic neurons

open access: yesScientific Reports, 2020
Olanzapine is a second-generation antipsychotic (AP) drug commonly prescribed for the treatment of schizophrenia. Recently, olanzapine has been found to cause brain tissue volume loss in rodent and primate studies; however, the underlying mechanism ...
Z. Boz   +3 more
semanticscholar   +1 more source

Entry of the antipsychotic drug, olanzapine, into the developing rat brain in mono- and combination therapies [version 2; peer review: 2 approved]

open access: yesF1000Research, 2023
Background: Olanzapine is used to treat schizophrenia and bipolar disorder in women of childbearing age. Continuation of psychotropic medications throughout pregnancy and lactation is often required as cessation could be dangerous for both mother and ...
Mark Habgood   +5 more
doaj   +1 more source

Risk of Mortality (including Sudden Cardiac Death) and Major Cardiovascular Events in Users of Olanzapine and Other Antipsychotics: A Study with the General Practice Research Database. [PDF]

open access: yes, 2013
Objective. Assess risk of cardiac events and mortality among users of olanzapine and other antipsychotics relative to nonusers. Methods. The General Practice Research Database was used to identify cohorts of antipsychotic users and nonusers with ...
Brunner, Elizabeth   +8 more
core   +3 more sources

Macrophage-derived secretome is sufficient to confer olanzapine-mediated insulin resistance in human adipocytes

open access: yesComprehensive Psychoneuroendocrinology, 2021
Objective: Olanzapine and Aripiprazole are widely used second-generation antipsychotic drugs. Olanzapine, more than Aripiprazole, leads to considerable metabolic side effects including obesity and diabetes.
Priya Dipta   +9 more
doaj   +1 more source

Intramuscular Olanzapine and Intramuscular Haloperidol in Acute Schizophrenia: Antipsychotic Efficacy and Extrapyramidal Safety During the First 24 Hours of Treatment [PDF]

open access: yes, 2003
To determine the antipsychotic efficacy and extrapyramidal safety of intramuscular (IM) olanzapine and IM haloperidol during the first 24 hours of treatment of acute schizophrenia.
Alaka, Karla.   +14 more
core   +1 more source

Mitigation of Olanzapine-Induced Weight Gain With Samidorphan, an Opioid Antagonist: A Randomized Double-Blind Phase 2 Study in Patients With Schizophrenia.

open access: yesAmerican Journal of Psychiatry, 2019
OBJECTIVE Preclinical evidence and data from a proof-of-concept study in healthy volunteers suggest that samidorphan, an opioid antagonist, mitigates weight gain associated with olanzapine.
William F. Martin   +7 more
semanticscholar   +1 more source

Olanzapine-induced restless leg syndrome (Willis–Ekbom disease): A case report

open access: yesSAGE Open Medical Case Reports, 2022
Restless leg syndrome, also known as Willis–Ekbom disease, is a neurological sensorimotor disorder accompanied by an irresistible urge to move the legs with a fluctuating course of symptoms.
Soumitra Das   +5 more
doaj   +1 more source

Could dopamine agonists aid in drug development for anorexia nervosa? [PDF]

open access: yes, 2014
Anorexia nervosa is a severe psychiatric disorder most commonly starting during the teenage-years and associated with food refusal and low body weight. Typically there is a loss of menses, intense fear of gaining weight, and an often delusional quality ...
Frank, Guido KW
core   +2 more sources

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