Results 81 to 90 of about 1,001,282 (315)
Background: the proportion of older people is increasing worldwide. Globally, it is estimated that older people (those 60 years or older) constitute more than 11% of the population.
Kyobutungi, Catherine +7 more
core +1 more source
EPIDEMIOLOGICAL PROFILE OF OLDER ADULTS WITH HIV IN THE STATE OF PARANÁ IN 2024
Introduction/objective: The increase in population longevity has brought to light public health issues that affect older adults, including infection by the human immunodeficiency virus (HIV). The analysis of the epidemiological profile of this population
Caroline Hermann +9 more
doaj +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
The long-run impacts of adult deaths on older household members in Tanzania [PDF]
HIV/AIDS is drastically changing the demographic landscape in high-prevalence countries in Africa. The prime-age adult population bears the majority of the mortality burden.
Adhvaryu, Achyuta R., Beegle, Kathleen
core
ObjectiveAnalyze the distribution equilibrium of older adult meal service facilities in mainland China and explore the factors influencing their distribution.MethodsUse Python to obtain data on older adult meal service facilities, and analyze the equity ...
Feng Wang +3 more
doaj +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
What you know can influence what you are going to know (especially for older adults) [PDF]
Stimuli related to an individual’s knowledge/ experience are often more memorable than abstract stimuli, particularly for older adults. This has been found when material that is congruent with knowledge is contrasted with material that is incongruent
Maylor, EA +4 more
core +1 more source
BackgroundUnder the background of population aging in China, the demand for older-adult care services and products is growing, and the older-adult care industry has great development prospects.
Xiangwei Zhang +5 more
doaj +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Polypharmacy in the HIV-infected older adult population
Lauren J Gleason1, Amneris E Luque2, Krupa Shah1 1Division of Geriatrics and Aging, Highland Hospital, Rochester, NY, USA; 2Division of Infectious Disease, Department of Medicine, University of Rochester School of Medicine and Dentistry, Rochester, NY ...
Gleason LJ, Luque AE, Shah K
core

