Results 101 to 110 of about 3,539,834 (301)

Lifelong learning and adult education in Japan

, 2022
The purposes and implementation of adults’ lifelong education (LLE) has been shaped by two imperatives: i) neoliberal reforms and ii) focuses on employability and economic outcomes. This has led to LLE taking similar pathways across many countries, i.e.,
Le, Ahn Ha, Billett, Stephen
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Current application and future pathways of smart older adult care services in China

Frontiers in Digital Health
The aging problem in China has been more and more severe so that traditional older adult care service models are difficult to meet the growing demands of the older adult population.
Jie Xue
doaj   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Spatial–temporal evolution and associated factors of older adult care institutions in Shanghai

Frontiers in Public Health
BackgroundShanghai is one of the first Chinese cities to tackle the challenges presented by an aging population. In response, the city has been actively seeking solutions for older adult care within a metropolitan context.
Xingxing Yin, Jinghang Cui, Yifan Wu, Mingxuan Cui, Kun Li, Haoxiang Guo   +5 more
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Prognosis of Older Adult Patients Suffering from Atrial Fibrillation and Hypokalemia

, 2023
Xue-Dong Wang, Yu Wang, Jing Liu, Ji-Wen Yao, Jing Zhang, Yi-Nan Zhang Department of Cardiology, Beijing Hepingli Hospital, Beijing, People’s Republic of ChinaCorrespondence: Xue-Dong Wang, Department of Cardiology, Beijing Hepingli Hospital, No.
Liu J, Zhang J, Wang XD, Wang Y, Zhang YN, Yao JW   +5 more
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The impact of social participation on mental health among the older adult in China: an analysis based on the mental frailty index

Frontiers in Public Health
ObjectivesSocial participation and the psychological well-being of the older adult are correlated. A substantial body of research has delineated the relationship between social participation and the mental health of older adults, while the indicators for
Maiyu Jing, Qianqian Wang, Yuheng Jia, Xiaoyong Yu, Kan Tian   +4 more
doaj   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Researching men's sheds in community contexts in Australia : What does it suggest about adult education for older men?

, 2008
This paper reports on research into community-based men's sheds in Australia, focusing on how regular activity in these sheds impacts on the informal learning experiences of the mainly older men who use them.
Golding, Barry
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