Results 121 to 130 of about 1,001,282 (315)

Factors influencing mutual support among older people in China: a cross-sectional study

Frontiers in Public Health
AimsTo investigate the willingness of Xiamen’s older adult community members to participate in mutual support for the older adult, and to explore the factors that influence their willingness to participate.BackgroundMutual support in old age care fully ...
Lichun Xu, Lichun Xu, Lichun Xu, Liyu Lin, Xiaojin Huang, Aixuan Guan, Lianfang Cheng, Yicen Zheng, Shuyi Zhang   +8 more
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Models of Inter Professional Working for older people living at home: a survey and review of the local strategies of English health and social care statutory organisations

, 2011
Background Most services provided by health and social care organisations for older people living at home rely on interprofessional working (IPW). Although there is research investigating what supports and inhibits how professionals work together, less ...
Drennan, Vari, Drennan, V, Iliffe Steve, Scheibl, Fiona, Manthorpe, J, Gage, H, Gage, Heather, Dhrushita Shah, Shah, D, Heather Gage, Goodman Claire, Fiona Scheibl, Manthorpe Jill, Iliffe, S, Shah, Dhrushita, Iliffe, Steve, Jill Manthorpe, Goodman, Claire, Manthorpe, Jill; id_orcid, Shah Dhrushita, Scheibl, F, Vari Drennan, Goodman, C, Gage Heather, Drennan Vari, Scheibl Fiona, Claire Goodman, Manthorpe, Jill, Steve Iliffe   +28 more
core   +1 more source

The impact of social participation on mental health among the older adult in China: an analysis based on the mental frailty index

Frontiers in Public Health
ObjectivesSocial participation and the psychological well-being of the older adult are correlated. A substantial body of research has delineated the relationship between social participation and the mental health of older adults, while the indicators for
Maiyu Jing, Qianqian Wang, Yuheng Jia, Xiaoyong Yu, Kan Tian   +4 more
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Family caregivers’ perception and response to COVID-19 in caring for older adults with chronic diseases: A qualitative study

Lentera Perawat
Background: The older adult is the vulnerable group to infecting COVID-19 and most of them live with their families. The family must take care of them while they face various problems during the pandemic.
Bahtiar Bahtiar, Nurlaila Fitriani, Dwi Nopriyanto, Ida Ayu Kade Sri Widiastuti, Arief Andriyanto, Ikbal Fradianto, Eriyono Budi Wijoyo   +6 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Adjuvant Chemotherapy for Breast Cancer in Older Adult Patients

Ying Gao,1,2 Jie Hao,1 Zhendong Zhang1 1Department of Breast and Thyroid Surgery, Tianjin Union Medical Center, Tianjin, 300121, People’s Republic of China; 2Department of Thyroid and Neck Cancer, Tianjin Medical University Cancer Hospital, National ...
Hao J, Zhang Z, Gao Y
core  

Older Adult Activity Study

To set a price on the value of social inclusion is difficult. Mobility is understood as one of the major prerequisites for social inclusion. For this project, for scenario 1, we investigate off-the-shelf wearable technologies that we hypothesise enable a
Morrison, Ann
core   +1 more source