Results 51 to 60 of about 2,390,893 (252)

Safety and Effectiveness of a High‐Dose, Tailored Tissue Plasminogen Activator Therapy Protocol: A Joint Pediatric Hematology and Cardiac ICU Quality Improvement Initiative Analysis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Pediatric thromboembolism is increasingly encountered in critical care. Systemic thrombolysis with tissue plasminogen activator (tPA) facilitates vessel or valve patency, yet pediatric‐specific protocols remain undefined, and safety concerns persist. Objective To evaluate the efficacy and safety of a tailored, prolonged systemic tPA
Eran Shostak, Oded Gilad, Yael Feinstein, Sigal Nakav, Ofer Schiller, Joanne Yacobovich   +5 more
wiley   +1 more source

The AdHOC study of older adults' adherence to medication in 11 countries [PDF]

, 2005
Objective: Authors investigated, cross-nationally, the factors, including demographic, psychiatric ( including cognitive), physical, and behavioral, determining whether older people take their prescribed medication.
Cooper, Claudia, Katona, Cornelius, Cordula Wagner, Daniela Fialova, Wagner, C., Cornelius Katona, Wagner, Cordula, Livingston, G., Carpenter, G. Iain, Gill Livingston, Cooper, C., Katona, C., Fialova, Daniela, Carpenter, I., Schroll, M., Iain Carpenter, Claudia Cooper, Marianne Schroll, Livingston, Gill, Schroll, Marianne, Fialova, D.   +20 more
core   +1 more source

Neuropsychological and Educational Outcomes in Shwachman–Diamond Syndrome—A Report From the North American Shwachman–Diamond Syndrome Registry

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Shwachman–Diamond syndrome (SDS) is a rare autosomal recessive ribosomopathy characterized by bone marrow failure and multisystem involvement, with emerging evidence of associated neurocognitive impairment. Methods We conducted a retrospective study of 240 individuals with biallelic Shwachman–Bodian–Diamond syndrome (SBDS) mutations
Jane Koo, Melissa Gerstle, Leah Cheng, Richard Cooper, Katherine Coyne, Claire Dusa, Naomi E. Joffe, Diana Schwarz, Sarah Steltz, Akiko Shimamura, Kasiani C. Myers, Thea Quinton   +11 more
wiley   +1 more source

Multimodal and longitudinal characterization of distinct tau and atrophy clusters in Alzheimer’s disease spectrum

Scientific Reports
Neuropathological and neuroimaging studies have identified several (endo-)phenotypes of Alzheimer’s disease (AD), suggesting a substantial heterogeneity in cerebral atrophy and tau spreading patterns. We included in our study a total of 320 participants,
Boris-Stephan Rauchmann, Ersin Ersözlü, Dorothea Luedecke, Nicolai Franzmeier, Robert Perneczky   +4 more
doaj   +1 more source

Structural equation modeling of symptom clusters and health-related quality of life among patients with advanced colorectal cancer receiving chemotherapy in Bangkok, Thailand

Belitung Nursing Journal
Background: Patients with advanced colorectal cancer (CRC) receiving chemotherapy experience multiple symptoms due to both disease progression and complications of treatment. These symptoms affect the physical, psychological, and social aspects of health-
Savitree Suratako, Yaowarat Matchim, Mary Quinn Griffin   +2 more
doaj   +1 more source

Survival After Hematopoietic Stem Cell Transplantation in Diamond–Blackfan Anemia Syndrome: The Role of Iron Overload—A Systematic Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT We assessed the effect of iron overload (IO) on mortality and complications following hematopoietic stem cell transplantation (HSCT) in patients with Diamond–Blackfan anemia syndrome (DBAS) in a systematic review of individual participant data and cohort data from observational studies.
Geoffrey Z. L. Kuppens, Evangelia Kiakou, Lieke de Zwart, Maurizio Miano, Eduard J. van Beers, Marc Bierings, Marije Bartels   +6 more
wiley   +1 more source

The role of executive attention in healthy older adults' concurrent walking and counting [PDF]

, 2014
Completing activities of daily life relies on using both cognitive and physical resources efficiently, but these are affected by age. This may be due either to an age-related reduction in the resources we have available for carrying out tasks or to a ...
Maclean, Linda MacArthur
core   +2 more sources

Understanding self-harm in older adults: a qualitative study [PDF]

, 2019
Background Self-harm is the leading risk factor for suicide, with elevated rates reported amongst older populations. This study explores how older adults experience self-harm, identifying factors leading to self-harm.
Lisa Dikomitis, Opeyemi O. Babatunde, M. Isabela Troya, Carolyn A. Chew-Graham, Bernadette Bartlam   +4 more
core   +1 more source

Referral Practices and Utilisation of Paediatric Oncology Physiotherapy Services in Ghana: A Cross‐Sectional Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Physical rehabilitation is highly recognised in improving the quality of life of cancer survivors through prehabilitation, sequelae management and palliative care, yet its integration into routine care in Ghana has not been characterised, leading to potential gaps in service access.
Dorothy Ekua Adjabu, Philip Junior Nyarko, Precious Madzimbe, Kofi Adesi Kyei, Tawagidu Mohammed, Sandra Banini   +5 more
wiley   +1 more source

The progress in the field of clinical staging for mental disorders within the last decade: an updated systematic review

Frontiers in Psychiatry
IntroductionClinical staging aims to refine psychiatric diagnosis by describing mental disorders on a continuum of disorder progression, with the pragmatic goal of improved treatment planning and outcome prediction.
Sharon L. Clarke, Sharon L. Clarke, Nicole Soons, Arjan C. Videler, Arjan C. Videler, Sebastiaan P. J. van Alphen, Sebastiaan P. J. van Alphen, Henricus Van, Linda Dil, Laurens Pappijn, Sven Corbeij, Beau Broekhof, Beau Broekhof, Andrew M. Chanen, Andrew M. Chanen, Joost Hutsebaut, Joost Hutsebaut   +16 more
doaj   +1 more source