Results 61 to 70 of about 1,167,435 (311)

Multimodal and longitudinal characterization of distinct tau and atrophy clusters in Alzheimer’s disease spectrum

Scientific Reports
Neuropathological and neuroimaging studies have identified several (endo-)phenotypes of Alzheimer’s disease (AD), suggesting a substantial heterogeneity in cerebral atrophy and tau spreading patterns. We included in our study a total of 320 participants,
Boris-Stephan Rauchmann, Ersin Ersözlü, Dorothea Luedecke, Nicolai Franzmeier, Robert Perneczky   +4 more
doaj   +1 more source

Structural equation modeling of symptom clusters and health-related quality of life among patients with advanced colorectal cancer receiving chemotherapy in Bangkok, Thailand

Belitung Nursing Journal
Background: Patients with advanced colorectal cancer (CRC) receiving chemotherapy experience multiple symptoms due to both disease progression and complications of treatment. These symptoms affect the physical, psychological, and social aspects of health-
Savitree Suratako, Yaowarat Matchim, Mary Quinn Griffin   +2 more
doaj   +1 more source

Experiences of in-home evaluation of independent living technologies for older adults [PDF]

, 2009
Evaluating home-based independent living technologies for older adults is essential. Whilst older adults are a diverse group with a range of computing experiences, it is likely that many of this user group may have little experience with technology and ...
Bailey, Cathy, Dromey, Ben, Doyle, Julie
core  

Vaccination in older adults with cancer and older cancer survivors [PDF]

, 2021
Vaccination is one of the most effective means of preventing infections and should be widely promoted, especially in immunocompromised patients, such as older adults with cancer and older cancer survivors.
Negrete-Najar,Juan Pablo, Juan Pablo Negrete-Najar, Soto-Perez-de-Celis,Enrique, Arreola-Rodríguez,Alejandro, Ana Patricia Navarrete-Reyes, Enrique Soto-Perez-de-Celis, Alejandro Arreola-Rodríguez, Navarrete-Reyes,Ana Patricia   +7 more
core   +1 more source

Feasibility and Safety of Somato‐Cognitive Coordination Therapy for Cerebellar Ataxia Following Pediatric Brain Tumor Treatment

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Cerebellar ataxia after pediatric brain tumor treatment can cause persistent gait, balance, and speech impairment, yet no established rehabilitation strategy exists. Somato‐cognitive coordination therapy (SCCT) is a virtual reality–guided intervention designed to promote sensorimotor integration through visually constrained reaching
Masanobu Takeuchi, Takashi Matsuzawa, Jun Yamanishi, Masahiro Yoshitomi, Junji Ikeda, Shin‐Ichi Tsujimoto, Yasuteru Yamaguchi, Norio Shiba, Dhroov Pathare, Ayumi Kato, Masahiko Hara   +10 more
wiley   +1 more source

Prevalence of 21 Physician‐Defined Severe Toxicities Following Childhood Acute Lymphoblastic Leukemia Treatment: Australian Retrospective Cohort Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Acute lymphoblastic leukemia (ALL) is the most common pediatric cancer, with an overall survival now surpassing 90% in developed countries. However, treatments are not without adverse effects. In this study, we apply the severe toxicity‐free survival (STFS) framework to determine the prevalence of 21 physician‐defined severe ...
Lane Collier, Brittany Grantham, Camilla Grud Nielsen, Louise Lundgren, Liv Andrés‐Jensen, Kjeld Schmiegelow, Chris Selman, Gareth Ball, Elyse Passmore, David A. Elliott, Rachel Conyers   +10 more
wiley   +1 more source

The progress in the field of clinical staging for mental disorders within the last decade: an updated systematic review

Frontiers in Psychiatry
IntroductionClinical staging aims to refine psychiatric diagnosis by describing mental disorders on a continuum of disorder progression, with the pragmatic goal of improved treatment planning and outcome prediction.
Sharon L. Clarke, Sharon L. Clarke, Nicole Soons, Arjan C. Videler, Arjan C. Videler, Sebastiaan P. J. van Alphen, Sebastiaan P. J. van Alphen, Henricus Van, Linda Dil, Laurens Pappijn, Sven Corbeij, Beau Broekhof, Beau Broekhof, Andrew M. Chanen, Andrew M. Chanen, Joost Hutsebaut, Joost Hutsebaut   +16 more
doaj   +1 more source

Sustained Therapeutic Efficacy of Intravenous Plasminogen Concentrate in Pediatric Patients With Type 1 Plasminogen Deficiency: An Analysis of Dosing Parameters and Clinical Outcomes

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Type 1 plasminogen deficiency (PLGD‐1) is an ultra‐rare autosomal recessive disorder caused by variants in the PLG gene and affects approximately 1.6 individuals per million. The condition is characterized by decreased plasminogen levels and impaired function, resulting in fibrin‐rich lesions on mucous membranes throughout the body.
Charles Nakar, Karen Thibaudeau, Mary Mathias, Heather McDaniel, Madlen Reschke, Klaus Tenbrock, Joseph M. Parker, Amy Shapiro   +7 more
wiley   +1 more source

Rational Use of Herbal Products in Pediatric Patients Treated With Anticancer Drugs in the European Union

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction The use of herbal medical preparation (HMP) is rising among pediatric oncology patients, often to manage treatment‐related symptoms. Their effectiveness remains uncertain, and the risk of herb–drug interactions is underestimated.
Orianne Mahot, Mathieu Corvaisier, Laurence Spiesser‐Robelet, Mylène Duplan, Isabelle Pellier, Delphine Bourneau‐Martin, Séverine Derbré   +6 more
wiley   +1 more source

What can local authorities do to improve the social care-related quality of life of older adults living at home? Evidence from the Adult Social Care Survey [PDF]

, 2014
Local authorities spend considerable resources on social care at home for older adults. Given the expected growth in the population of older adults and budget cuts on local government, it is important to find efficient ways of maintaining and improving ...
van der Horst, H.E., Bosmans, J.E., Ostelo, R.W.J.G., Van Leeuwen, Karen, van der Horst, H E, Jansen, A.P.D., Malley, Juliette, Ostelo, R W, Jansen, A, Bosmans, J E, Netten, Ann, Netten, A., Bosmans, J.E.; id_orcid, Ostelo, R.W., van Leeuwen, K.M., Malley, J., Ostelo, R.W.J.G.; id_orcid   +16 more
core   +1 more source