Results 81 to 90 of about 9,063,075 (357)

Deep Sequencing of FLT3‐ITD Enables Response Evaluation and Post‐Treatment Monitoring in Childhood AML: An Exploratory Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background An internal tandem duplication in the gene encoding Fms‐like tyrosine kinase 3 (FLT3‐ITD) is associated with high relapse risk and poor prognosis in acute myeloid leukemia (AML) and plays a crucial role in treatment decisions. Measurable residual disease (MRD) analysis of FLT3‐ITD during and after treatment has shown prognostic ...
Sofie Johansson Alm   +11 more
wiley   +1 more source

Older Carers and Adults with Learning Disabilities: Stress and Reciprocal Care

open access: yes, 2010
People with a learning disability have an increased longevity. The majority of adults with a learning disability live with their parents which means that many of these parents are themselves elderly people.
Gant, Valerie
core   +1 more source

The AdHOC study of older adults' adherence to medication in 11 countries [PDF]

open access: yes, 2005
Objective: Authors investigated, cross-nationally, the factors, including demographic, psychiatric ( including cognitive), physical, and behavioral, determining whether older people take their prescribed medication.
Cooper, Claudia   +20 more
core   +1 more source

Multimodal and longitudinal characterization of distinct tau and atrophy clusters in Alzheimer’s disease spectrum

open access: yesScientific Reports
Neuropathological and neuroimaging studies have identified several (endo-)phenotypes of Alzheimer’s disease (AD), suggesting a substantial heterogeneity in cerebral atrophy and tau spreading patterns. We included in our study a total of 320 participants,
Boris-Stephan Rauchmann   +4 more
doaj   +1 more source

Structural equation modeling of symptom clusters and health-related quality of life among patients with advanced colorectal cancer receiving chemotherapy in Bangkok, Thailand

open access: yesBelitung Nursing Journal
Background: Patients with advanced colorectal cancer (CRC) receiving chemotherapy experience multiple symptoms due to both disease progression and complications of treatment. These symptoms affect the physical, psychological, and social aspects of health-
Savitree Suratako   +2 more
doaj   +1 more source

Resistance Training for Older Adults: Position Statement From the National Strength and Conditioning Association.

open access: yesJournal of Strength and Conditioning Research, 2019
Fragala, MS, Cadore, EL, Dorgo, S, Izquierdo, M, Kraemer, WJ, Peterson, MD, and Ryan, ED. Resistance training for older adults: position statement from the national strength and conditioning association.
Maren S Fragala   +6 more
semanticscholar   +1 more source

The Impact of Sheltering in Place During the COVID-19 Pandemic on Older Adults’ Social and Mental Well-Being

open access: yesThe journals of gerontology. Series B, Psychological sciences and social sciences, 2020
Objectives We examined whether social isolation due to the COVID-19 shelter-in-place orders was associated with greater loneliness and depression for older adults, and, if so, whether declines in social engagement or relationship strength moderated that ...
A. Krendl, B. Perry
semanticscholar   +1 more source

Time Toxicity in Wilms Tumor: Quantifying the Burden of Healthcare Interaction in the First Year After Diagnosis

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Wilms tumor (WT) treatment imposes a significant time burden on patients and their families. Time toxicity is a patient‐centered metric that quantifies the burden of healthcare interaction. We sought to define time toxicity in the first year after diagnosis of WT and hypothesized that it would increase as tumor stage and treatment ...
Caleb Q. Ashbrook   +6 more
wiley   +1 more source

Older Adults and the Mental Health Effects of COVID-19.

open access: yesJournal of the American Medical Association (JAMA), 2020
However, this reaction might have been par-tially countered by a range of coping mechanisms. In a mixed-methods study involving 73 older adults 7 (mean age, 69.2 years) with known depression or anxiety who had demonstrated resilience (ie, no worsening ...
I. Vahia, D. Jeste, C. Reynolds
semanticscholar   +1 more source

NSSI in Older Adults

open access: yes, 2023
Abstract This chapter explores the epidemiology of nonsuicidal self-injury (NSSI) in older adults. It explains how a systematic review presents the risk and protective factors of NSSI among the elderly population, referencing the selection process of the Meta-Analyses and Systematic Reviews of Observational Studies in Epidemiology.
Van Hove, Lisa   +6 more
openaire   +2 more sources

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