Results 101 to 110 of about 2,537,778 (297)
DSTIntrodução: O envelhecimento populacional apresenta implicações na saúde para além de aspectos individuais. Pessoas com 50 anos ou mais podem apresentar menor percepção de risco, menor acesso a estratégias preventivas e maior vulnerabilidade estrutural ...
Denise Eliziana de Souza +3 more
doaj +1 more source
Engagement of older adults in higher education: International perspectives from New Zealand and Scotland [PDF]
, 2012 This article explores the issue of older adults’ access to and participation in higher education in two countries, Aotearoa New Zealand and Scotland. It discusses older adults’ engagement with regard to patterns of participation and provision, using a ...
Findsen, Brian
core +1 more source
FEBS Letters, EarlyView.Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
Older adults and sport and physical activity professionals in Spain [PDF]
, 2010 Presence of monitors in physical activities and sports practiced by adults older than 64 years of age in Spain is analyzed in this research. The objective of this study is to determine the existence of monitors in relation to the sociodemographic ...
Campos Izquierdo, Antonio +4 more
core +3 more sources
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
BMC NursingIntroduction Nurse-led preventive home visiting programmes can improve health-related outcomes in community-dwelling older adults, but they have not proven to be cost-effective.
Iria Dobarrio-Sanz +5 more
doaj +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
BMC Health Services ResearchBackground Relocations within and between nursing homes often induce stress, anxiety, and depression in residents and cause additional workload for and burnout in staff.
Damien S. E. Broekharst +4 more
doaj +1 more source
Biomechanics of stair descent in older adults [PDF]
, 2005 Negotiating stairs is one of the most difficult activities of daily living faced by older adults. Many researchers have studied the cardiovascular and musculoskeletal demands of stair ascent but there is little research on the biomechanics of stair ...
Hood, Victoria, Nicol, Alexander
core