Results 101 to 110 of about 9,063,075 (357)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Association between dependence on activities of daily living and frailty in older people: a comparative study using the clinical-functional vulnerability index-20 and the frailty phenotype

Archives of Gerontology and Geriatrics Plus
Objective: This study aimed to compare the strength of associations between dependence on basic activities of daily living (BADL) and instrumental activities of daily living (IADL) and frailty, assessed by the Clinical-Functional Vulnerability Index-20 ...
Larissa Franciny Souza, PT, Camila Silva de Melo, PT, Artenizia Criste Lima, RDN, Bruno de Souza Moreira, PT, PhD, Henrique Silveira Costa, PT, PhD, Alessandra de Carvalho Bastone, PT, PhD   +5 more
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Differences in physical-fitness test scores between actively and passively recruited older adults: consequences for norm-based classification [PDF]

, 2002
This study investigated differences in physical-fitness test scores between actively and passively recruited older adults and the consequences thereof for norm-based classification of individuals.
van Heuvelen, M.J.G., Stevens, M., Stevens, M.; id_orcid, Kempen, G.I.J.M.   +3 more
core  

Reproducibility and validity of adapted clinical tests for the assessment of muscle strength in community-dwelling older adults living with Alzheimer’s disease

BMC Geriatrics
Background Older adults living with Alzheimer’s disease (AD) have impaired executive functions and can therefore have greater difficulty following the instructions of assessment tests.
Marcos Paulo Braz de Oliveira, Letícia Bojikian Calixtre, Natália Oiring de Castro Cezar, Carla Lima-Truax, Brendon David Truax, Anielle Cristhine de Medeiros Takahashi, Tatiana de Oliveira Sato, Paulo Henrique Silva Pelicioni, Paula Regina Mendes da Silva Serrão, Larissa Pires de Andrade   +9 more
doaj   +1 more source

Analysis of attempted suicide episodes presenting to the emergency department: comparison of young, middle aged and older people

International Journal of Mental Health Systems, 2020
Background Attempted suicide remains difficult for clinicians to predict with some established risk factors. We investigate the detailed characteristics of attempted suicide especially according to age and methods of suicide attempts.
Soo Hyun Kim, Han Joon Kim, Sang Hoon Oh, Kyungman Cha   +3 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Wooncomplexen voor ouderen: Sociale kwaliteit ontstaat niet vanzelf.

Journal of Social Intervention, 2018
Wooncomplexen voor ouderen: sociale kwaliteit ontstaat niet vanzelfDe Nederlandse overheid stimuleert dat ouderen zo lang mogelijk zelfstandig blijven wonen. De meeste ouderen willen dit ook, mits aan bepaalde voorwaarden is voldaan.
Anja Machielse, Wander van der Vaart, Pien Bos   +2 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Engagement of older adults in higher education: International perspectives from New Zealand and Scotland

, 2012
This article explores the issue of older adults’ access to and participation in higher education in two countries, Aotearoa New Zealand and Scotland. It discusses older adults’ engagement with regard to patterns of participation and provision, using a ...
Findsen, Brian
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