Results 61 to 70 of about 7,347,462 (301)

Older people’s experiences of mistreatment and abuse [PDF]

, 2012
The number of older people who are at risk of mistreatment and abuse is likely to grow as the proportion of older people in the population continues to increase. Prevalence evidence indicates that approximately 2.2 per cent of older people in Ireland
Lafferty, Attracta, Lyons, Imogen, Treacy, Margaret P., Drennan, Jonathan, Fealy, Gerard   +4 more
core  

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

A literature review to explore integrated care for older people [PDF]

, 2005
Purpose: This paper reports on some of the findings of a literature review commissioned to explore integrated care for older people. Methods: The process of revising included finding and selecting literature from multidisciplinary sources, and ...
Sue Childs, Childs, Sue, Reed, Jan, Cook, Glenda, McCormack, Brendan, Jan Reed, Brendan McCormack, Glenda Cook   +7 more
core   +1 more source

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

FEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao, Xiaoting Kang, Lulu Meng, Shaoxuan Zhang, Qiujie Li, Jinyu Zhou, Mengyue Xue, Chu Li, Hua Zhu, Pengzhou Hang, Jing Zhao   +10 more
wiley   +1 more source

Randomized crossover trial of a modified ketogenic diet in Alzheimer’s disease

Alzheimer’s Research & Therapy, 2021
Background Brain energy metabolism is impaired in Alzheimer’s disease (AD), which may be mitigated by a ketogenic diet. We conducted a randomized crossover trial to determine whether a 12-week modified ketogenic diet improved cognition, daily function ...
Matthew C. L. Phillips, Laura M. Deprez, Grace M. N. Mortimer, Deborah K. J. Murtagh, Stacey McCoy, Ruth Mylchreest, Linda J. Gilbertson, Karen M. Clark, Patricia V. Simpson, Eileen J. McManus, Jee-Eun Oh, Satish Yadavaraj, Vanessa M. King, Avinesh Pillai, Beatriz Romero-Ferrando, Martijn Brinkhuis, Bronwyn M. Copeland, Shah Samad, Shenyang Liao, Jan A. C. Schepel   +19 more
doaj   +1 more source

Gait, mobility, and falls in older people [PDF]

, 2012
My doctoral thesis contributes to the understanding of gait, mobility, and falls in older people. All presented projects investigated the most prominent and sensitive markers for fall-related gait changes, that is gait velocity and gait variability ...
Gschwind, Yves Josef
core   +1 more source

Determinants of undergraduate bioscience engagement: Validating attendance barriers and classroom spatial behaviour across institutions

FEBS Open Bio, EarlyView.
Student engagement extends beyond simple attendance. Across 891 bioscience students from three universities, attendance behaviour was associated mainly with structural influences, whereas classroom spatial behaviour reflected affective and sensory factors.
Nigel Page, Rachel J. Hunt, Lauren J. Albee, Daniel Berwick, Alison Snape   +4 more
wiley   +1 more source

Hospital admissions in older people with visual impairment in Britain. [PDF]

, 2008
BACKGROUND: We aimed to assess the risk of hospital admission associated with visual impairment in a representative sample of older people living in the community in Britain. DESIGN: Prospective study of hospital admission in a population-based sample of
Astrid E Fletcher, Evans, Jennifer R, Evans Jennifer R, Smeeth, Liam, Fletcher, Astrid E, Smeeth Liam, Jennifer R Evans, Fletcher Astrid E, Liam Smeeth   +8 more
core   +2 more sources

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Feasibility of the WHO Infection Prevention and Control Assessment Framework in long-term care facilities: a pilot study in the Netherlands

Antimicrobial Resistance and Infection Control
Background The World Health Organization’s Infection Prevention and Control Assessment Framework (IPCAF) is widely used to evaluate infection prevention and control (IPC) quality in hospitals, but IPC standards in long-term care facilities (LTCFs) are ...
K. Halonen, A. Haenen, M. Smalbrugge, L. W. van Buul, R. C. Wang, C. Schneeberger, D. W. Notermans, S. E. Geerlings, S. C. de Greeff   +8 more
doaj   +1 more source