Results 21 to 30 of about 926,771 (267)

Multidisciplinary Geriatric Rehabilitation Program for Patients with COPD-Induced Malnutrition and Muscle Wasting: A Case Series

COPD
Chronic obstructive pulmonary disease (COPD) induced malnutrition is a common and serious problem resulting in a higher risk of complications, exacerbations, and hospitalization.
Judith Ballemans, Marieke Geerars-van der Veen, Haniyeh Shoughiniya, Anouk van Loon, Ewout B. Smit   +4 more
doaj   +1 more source

Delirium in older people [PDF]

BMJ, 2007
Few ill health situations are more degrading to people of any age than loss of reasoning, faculties, and personhood. These are the unpleasant consequences of delirium—a common condition affecting ill older people, particularly those with some degree of dementia. It is characterised by recent onset of fluctuating inattention and confusion, linked to one
John, Young, Sharon K, Inouye
openaire   +2 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Long-term health conditions and their impact on people with sleep disturbances and dementia

BMC Geriatrics
Background Sleep disturbances are common for people with dementia and can be distressing for them and their family. People with dementia live with an average of five other long-term conditions (LTCs).
Penny Rapaport, Ankita Bhojwani, Lucy Webster, Sarah Amador, Malvika Muralidhar, Gill Livingston   +5 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Unraveling impaired awareness: experiences of people with dementia, Huntington’s disease and Korsakoff’s syndrome, and their informal caregivers

BMC Geriatrics
Background Impaired awareness occurs in people with dementia (DEM; Alzheimer’s disease (AD), including mixed AD/vascular), Huntington’s disease (HD) and Korsakoff’s syndrome (KS). We explored the experiences of these people and their informal caregivers,
Hester Fidder, Esther de Groot, Marike E. de Boer, Marina R. Ekkel, Ruth B. Veenhuizen, Martin Smalbrugge, Anouk M. van Loon   +6 more
doaj   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

FEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara, Kinga Skoczek, Elzbieta Pyza, Milena Damulewicz   +3 more
wiley   +1 more source

Audit and group feedback in nursing home physician groups: lessons learned from a qualitative study

BMC Health Services Research
Background Audit and group feedback (A&F) is an instrument used to encourage healthcare professionals to improve the quality of care. Clinical practice was audited against a set of criteria and fed back to a group by a facilitator.
Gary Y. C. Yeung, Charlotte A. W. Albers, Martin Smalbrugge, Martine C. de Bruijne, Patricia Jepma, Karlijn J. Joling   +5 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Psychological Impact of Hospital Discharge on the Older Person: A Systematic Review

Geriatrics
Introduction: Hospitalisation and prolonged length of stay is associated with deconditioning that risks adverse outcomes after discharge. Less is known about the psychological impact on older people after hospital discharge.
Yasmin Hussein, Sarah Edwards, Harnish P Patel   +2 more
doaj   +1 more source