Results 161 to 170 of about 1,235,469 (310)

Upskilling Older Workers.

open access: yes, 2016
Governments across much of the developed world are concerned to increase activity rates and employment among older workers and more generally to improve their position in the labour market. The use of education and training provision is prominent among the various policies that have been advocated for this purpose, and this paper evaluates the role ...
Mayhew, K, Elliott, M, Rijkers, B
openaire   +1 more source

Do Older Workers Lower IT-Enabled Productivity? Firm-Level Evidence from Germany [PDF]

open access: yes
The paper provides empirical evidence for the question whether firms’ ITenabled labour productivity is affected by the age structure of the workforce.
Irene Bertschek, Jenny Meyer
core  

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

Redefining social support: a scoping review of the effects of digital technologies on the social support of older workers. [PDF]

open access: yesBMC Public Health
Tofan CM   +11 more
europepmc   +1 more source

Temporary Help Services Employment in Portugal, 1995-2000 [PDF]

open access: yes
Whereas there is widespread belief that workers in temporary help services (THS) are subject to poorer working conditions, in particular pay, than comparable workers in the rest of the economy, there is little evidence on whether that is driven by the ...
Ana Rute Cardoso, Rene Boeheim
core  

The role of lipid metabolism in neuronal senescence

open access: yesFEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari   +2 more
wiley   +1 more source

Exploring Older Male Worker Labour Force Participation Across OECD Countries in the Context of Ageing Populations: A Reserve Army of Labour? [PDF]

open access: yes
The governments of many developed economies are confronting a number of policy issues associated with ageing populations. For example, pension reforms, increasing the labour force participation of older workers and increasing the standard retirement age ...
O'Brien, Martin
core  

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

open access: yesFEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li   +8 more
wiley   +1 more source

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

open access: yesFEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti   +3 more
wiley   +1 more source

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