Results 71 to 80 of about 265,817 (310)
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
IntroductionThere are still knowledge gaps relating to the interaction between digitalization, organizational changes, and the aging of the workforce. This study examines the impact of digitalization on older workers in the financial sector in Sweden and
Alena Křížková +4 more
doaj +1 more source
Eldre i arbeidslivet – slitenhet og yrkesavgang
Er eldre yrkesaktive mer slitne enn yngre og er slitenhet en årsak til at mange går av selv om det er flere år igjen til de når aldersgrensen? Dybdeintervjuer med ledere i nitten ulike virksomheter gir inntrykk av at dette er tilfellet.
Katharina Herlofson, Tale Hellevik
doaj +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Hidden Unemployment and Older Male Workers [PDF]
A number of policy reforms have recently been announced by the Commonwealth government to encourage greater labour force participation by older people in the context of an ageing society. These policy reforms are generally supply side in orientation such
O'Brien, Martin
core
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Does age matter in the social care workforce?
Context: With the population in England ageing, more people are living with complex physical and mental health needs and need care and support. As a result demand for care workers is increasing.Objective: This paper presents findings from qualitative ...
Valerie Lipman +2 more
doaj +3 more sources
This four-year longitudinal study examines how two facets of employability-professional ability and developmental proactivity-are linked to career events among workers ages 45 years and older.
Roobol, C. +3 more
doaj
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Workers' Compensation and Older Workers
After rising sharply in the 1980s, workers’ compensation costs and benefits declined during the 1990s. The recent decline may reflect, in part, a decline in the availability and adequacy of these benefits. Workers in the second half of their work lives are particularly likely to be affected by these changes.
Burton, John F., Spieler, Emily A.
openaire +2 more sources

