Results 231 to 240 of about 735,066 (303)

Is home always the best place to live? Preferences for place of residence and long-term care among the community-dwelling oldest old in Finland. [PDF]

Eur J Public Health
Pulkki JM, Aaltonen MS, Jylhä MK, Enroth LM.   +3 more
europepmc   +1 more source

Depressive symptoms are associated with hippocampal volume in the oldest-old: The LifeAfter90 study. [PDF]

Psychiatry Res Neuroimaging
Posis AIB, Rojas-Saunero LP, Lor Y, George KM, Gilsanz P, Maillard P, Corrada MM, Whitmer RA.   +7 more
europepmc   +1 more source

A Prospective Study of Individuals at Risk of Multiple Sclerosis Informs the Design of Primary Prevention Studies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective In multiple sclerosis, the optimal time for deploying a therapeutic intervention is before the central nervous system is damaged; given the success of trials treating the earliest stage of MS, the radiologically isolated syndrome, developing primary prevention strategies is an important next challenge.
Amy W. Laitinen, Ceren Tozlu, Tina Roostaei, Fatoumata Diallo, Kaho Onomichi, Jiyeon Son, Zongqi Xia, Philip L. De Jager   +7 more
wiley   +1 more source

Frequency and predictors of emergency department visits among the oldest old in Finland: the Vitality 90+ Study. [PDF]

BMC Health Serv Res
Abraham SB, Pulkki J, Aaltonen M, Jämsen E, Raitanen J, Enroth L.   +5 more
europepmc   +1 more source

Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina, Anna Marcé‐Grau, Barbara Masotto, Marta Codina, Lamia BenJemaa, Yasmina Elaribi, Mónica Martinez‐Gallo, Roger Colobran, Angel Sanchez‐Montañez, Irene Valenzuela, Yoshiko Murakami, Alfons Macaya   +11 more
wiley   +1 more source

Why the oldest old in China bypass primary care: culture, family, and health system limitations. [PDF]

Int J Qual Stud Health Well-being
Wamsiedel M, Li B.
europepmc   +1 more source

Epilepsy‐Associated Variants of a Single SCN1A Codon Exhibit Divergent Functional Properties

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Pathogenic variants in SCN1A, which encodes the voltage‐gated sodium channel NaV1.1, are associated with multiple epilepsy syndromes exhibiting a range of clinical severity. SCN1A variants are reported in different syndromes, including Dravet syndrome, which is associated with loss‐of‐function, whereas neonatal/infantile‐onset ...
Lanie N. Liebovitz, Christopher H. Thompson, Linda C. Laux, Alfred L. George Jr.   +3 more
wiley   +1 more source