Asian Journal of Pharmaceutical Sciences, 2016 The purpose of this study was to prepare the oleanolic acid–phospholipid complex (OA-PC) and then solidify it employing fumed silica by simple solvent evaporation technique to improve dissolution rate of oleanolic acid and oleanolic acid–phospholipid ...
Xiaoxu Yang +4 more
doaj +4 more sources
Oleanolic acid ethanol monosolvate [PDF]
Acta Crystallographica Section E, 2010 Crystals of the title compound (systematic name: 3β-hydroxyolean-12-en-28-oic acid ethanol monosolvate), C30H48O3·C2H5OH, were obtained from unsuccessful co-crystallization trials.
Anna Froelich, Andrzej K. Gzella
doaj +3 more sources
Targeting Oxidative Stress in Carcinogenesis: Oleanolic Acid and Its Molecular Pathways [PDF]
AntioxidantsThis narrative review aims to systematize the current knowledge on the dual role of reactive oxygen species and reactive nitrogen species in cancer processes, from their physiological function in redox signaling to their pathological impact in oxidative ...
Andrzej Günther +6 more
doaj +2 more sources
Study of the Stability and Anti-Inflammatory Activity of Paeonol–Oleanolic Acid Liposomes by Microfluidic Technology [PDF]
Foods(1) Background: This study used a microfluidic approach to prepare paeonol (PAE) liposomes with oleanolic acid (PAE-ONLs) instead of cholesterol (PAE-CNLs), aiming to reduce cholesterol levels and enhance stability and anti-inflammatory activity.
Xianzheng Ma +10 more
doaj +2 more sources
Oleanolic Acid: Extraction, Characterization and Biological Activity [PDF]
Nutrients, 2022 Oleanolic acid, a pentacyclic triterpenoid ubiquitously present in the plant kingdom, is receiving outstanding attention from the scientific community due to its biological activity against multiple diseases. Oleanolic acid is endowed with a wide range of biological activities with therapeutic potential by means of complex and multifactorial mechanisms.
Javier S Perona +2 more
exaly +4 more sources
Integrated transcriptome-metabolome analysis reveals oleanolic acid as a central regulator of heat stress adaptation in Rhododendron moulmainense [PDF]
BMC Plant BiologyBackground Alpine rhododendron has high ornamental value because of its vibrant color. However, growing them in urban landscapes is challenging, as high temperatures can slow the growth of Rhododendron roots and cause leaf burning.
Sijia Liu +9 more
doaj +2 more sources
Molecules, 2017 The increasing demand for natural products as an alternative therapy for chronic diseases has encouraged research into the pharmacological importance of bioactive compounds from plants.
Taiwo Betty Ayeleso +2 more
doaj +3 more sources
Facile Synthesis of Oleanolic Acid Monoglycosides and Diglycosides [PDF]
Molecules, 2008 Oleanolic acid and its glycosides are important natural products, possessing various attractive biological activities such as antitumor, antivirus and anti-inflammatory properties.
Mao-Sheng Cheng +4 more
doaj +3 more sources
Allosterically activating SHP2 by oleanolic acid inhibits STAT3–Th17 axis for ameliorating colitis [PDF]
Acta Pharmaceutica Sinica BSrc homology 2 domain-containing tyrosine phosphatase 2 (SHP2) is an essential tyrosine phosphatase that is pivotal in regulating various cellular signaling pathways such as cell growth, differentiation, and survival.
Jinbo Hu +8 more
doaj +2 more sources
Oleanolic acid combined with aspirin plays antitumor roles in colorectal cancer via the Akt/NFκB/IκBα/COX2 pathway [PDF]
Cell Death DiscoveryAmong the common malignancies, colorectal cancer (CRC) is often resistant to chemotherapy because of drug resistance and severe toxicity. Currently, aspirin is one of the most promising CRC chemopreventive drugs, both for primary prevention and for ...
Yulv Zhou +5 more
doaj +2 more sources