Results 31 to 40 of about 2,519,723 (219)

Synthesis and anti-cancer activity of a glycosyl library of N-acetylglucosamine-bearing oleanolic acid

open access: yes, 2017
N-Acetylglucosamine-bearing triterpenoid saponins (GNTS) were reported to be a unique type of saponins with potent anti-tumor activity. In order to study the structure-activity relationship of GNTS, 24 oleanolic acid saponins with ()-linked, ()-linked, ()
梁碧惠;顧記華   +1 more
core   +1 more source

Oxidation and Acetylation of Ursolic and Oleanolic Acids Isolated from Fragraea fragrans fruits; Antiproliferation of P388 Leukemia Cells

open access: yesIndonesian Journal of Chemistry, 2014
An interesting natural product chemistry aspect of Fragraea fragrans is that their fruits are richness with ursolic acid and its isomer oleanolic acid (3.05% of dried powder).
Dasril Basir   +3 more
doaj   +1 more source

A Validated Method for Standardization of the Bark of

open access: yesNatural Product Communications, 2010
Clerodendron serratum (Linn.) Moon (family: Verbenaceae) is used in Indian System of Medicine for asthma and cough. In the present study the extract of the bark of the plant was standardized using oleanolic acid as a marker.
Arunava Gantait   +4 more
doaj   +1 more source

Moroccan virgin olive oil triterpenes: HPLC-DAD-ELSD profiling and computational investigation of anti-diabetic potential [PDF]

open access: yesBioImpacts
Introduction: Diabetes mellitus (DM) is a chronic metabolic disorder characterized by hyperglycemia due to impaired insulin secretion or resistance. Conventional treatments like acarbose, miglitol, and voglibose inhibit carbohydrate-digesting enzymes but
Meryem Boutalaka   +8 more
doaj   +1 more source

Engineering of Yarrowia lipolytica for the production of plant triterpenoids: Asiatic, madecassic, and arjunolic acids

open access: yesMetabolic Engineering Communications, 2022
Several plant triterpenoids have valuable pharmaceutical properties, but their production and usage is limited since extraction from plants can burden natural resources, and result in low yields and purity.
Jonathan Asmund Arnesen   +6 more
doaj   +1 more source

From wild to tamed: Reimagining novel crops through omics and local plant diversity

open access: yesPLANTS, PEOPLE, PLANET, EarlyView.
The global food system faces growing pressure from climate change, biodiversity loss, and rising nutritional demands. Agriculture has increased yields but reduced crop diversity, flavor, and nutritional quality, leaving societies vulnerable and dependent on a narrow set of staple species.
Alexandra Sanfeliu Meliá   +1 more
wiley   +1 more source

Antiviral Activities of Oleanolic Acid and Its Analogues [PDF]

open access: yesMolecules, 2018
Viral diseases, such as human immune deficiency virus (HIV), influenza, hepatitis, and herpes, are the leading causes of human death in the world. The shortage of effective vaccines or therapeutics for the prevention and treatment of the numerous viral infections, and the great increase in the number of new drug-resistant viruses, indicate that there ...
Vuyolwethu Khwaza   +2 more
openaire   +3 more sources

Small Structural Differences Govern the Carbonic Anhydrase II Inhibition Activity of Cytotoxic Triterpene Acetazolamide Conjugates

open access: yesMolecules, 2023
Acetylated triterpenoids betulin, oleanolic acid, ursolic acid, and glycyrrhetinic acid were converted into their succinyl-spacered acetazolamide conjugates.
Toni C. Denner   +5 more
doaj   +1 more source

Oleanolic Acid‐Enriched Olive Oil Attenuates Kidney Function Decline in Patients With Type 2 Diabetes: Results From the OLTRAD Randomised Controlled Trial

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims Chronic kidney disease (CKD) is a major complication of type 2 diabetes mellitus (T2DM), driven in part by oxidative stress and the accumulation of advanced glycation end products (AGEs). Oleanolic acid (OA), a natural triterpene present in olive‐derived matrices, may modulate AGE metabolism.
Aída García‐González   +14 more
wiley   +1 more source

Interactions of Oleanolic Acid, Apigenin, Rutin, Resveratrol and Ferulic Acid with Phosphatidylcholine Lipid Membranes—A Spectroscopic and Machine Learning Study

open access: yesApplied Sciences, 2023
Biologically active compounds present in the diet can interact with biological membranes (such as cell membranes), changing their properties. Their mutual interactions can influence their respective activities. In this study, we analyzed the interactions
Krzysztof Dwiecki   +4 more
doaj   +1 more source

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