Results 31 to 40 of about 11,485 (176)

A systematic comparison of triterpenoid biosynthetic enzymes for the production of oleanolic acid in Saccharomyces cerevisiae.

open access: yesPLoS ONE, 2020
Triterpenoids are high-value plant metabolites with numerous applications in medicine, agriculture, food, and home and personal care products. However, plants produce triterpenoids in low abundance, and their complex structures make their chemical ...
Matthew P Dale   +3 more
doaj   +1 more source

Antiviral Activities of Oleanolic Acid and Its Analogues [PDF]

open access: yesMolecules, 2018
Viral diseases, such as human immune deficiency virus (HIV), influenza, hepatitis, and herpes, are the leading causes of human death in the world. The shortage of effective vaccines or therapeutics for the prevention and treatment of the numerous viral infections, and the great increase in the number of new drug-resistant viruses, indicate that there ...
Vuyolwethu Khwaza   +2 more
openaire   +3 more sources

Oxidation and Acetylation of Ursolic and Oleanolic Acids Isolated from Fragraea fragrans fruits; Antiproliferation of P388 Leukemia Cells

open access: yesIndonesian Journal of Chemistry, 2014
An interesting natural product chemistry aspect of Fragraea fragrans is that their fruits are richness with ursolic acid and its isomer oleanolic acid (3.05% of dried powder).
Dasril Basir   +3 more
doaj   +1 more source

A Validated Method for Standardization of the Bark of

open access: yesNatural Product Communications, 2010
Clerodendron serratum (Linn.) Moon (family: Verbenaceae) is used in Indian System of Medicine for asthma and cough. In the present study the extract of the bark of the plant was standardized using oleanolic acid as a marker.
Arunava Gantait   +4 more
doaj   +1 more source

Moroccan virgin olive oil triterpenes: HPLC-DAD-ELSD profiling and computational investigation of anti-diabetic potential [PDF]

open access: yesBioImpacts
Introduction: Diabetes mellitus (DM) is a chronic metabolic disorder characterized by hyperglycemia due to impaired insulin secretion or resistance. Conventional treatments like acarbose, miglitol, and voglibose inhibit carbohydrate-digesting enzymes but
Meryem Boutalaka   +8 more
doaj   +1 more source

Engineering of Yarrowia lipolytica for the production of plant triterpenoids: Asiatic, madecassic, and arjunolic acids

open access: yesMetabolic Engineering Communications, 2022
Several plant triterpenoids have valuable pharmaceutical properties, but their production and usage is limited since extraction from plants can burden natural resources, and result in low yields and purity.
Jonathan Asmund Arnesen   +6 more
doaj   +1 more source

Interactions of Oleanolic Acid, Apigenin, Rutin, Resveratrol and Ferulic Acid with Phosphatidylcholine Lipid Membranes—A Spectroscopic and Machine Learning Study

open access: yesApplied Sciences, 2023
Biologically active compounds present in the diet can interact with biological membranes (such as cell membranes), changing their properties. Their mutual interactions can influence their respective activities. In this study, we analyzed the interactions
Krzysztof Dwiecki   +4 more
doaj   +1 more source

Small Structural Differences Govern the Carbonic Anhydrase II Inhibition Activity of Cytotoxic Triterpene Acetazolamide Conjugates

open access: yesMolecules, 2023
Acetylated triterpenoids betulin, oleanolic acid, ursolic acid, and glycyrrhetinic acid were converted into their succinyl-spacered acetazolamide conjugates.
Toni C. Denner   +5 more
doaj   +1 more source

Olean-12-eno[2,3-c] [1,2,5]oxadiazol-28-oic acid (OEOA) induces G1 cell cycle arrest and differentiation in human leukemia cell lines. [PDF]

open access: yesPLoS ONE, 2013
Oleanolic acid (3β-hydroxy-olea-12-en-28-oic acid) is a natural pentacyclic triterpenoic acid found in many fruits, herbs and medicinal plants. In the past decade, increasing evidence has suggested that oleanolic acid exhibits inhibitory activities ...
Yu Pong Ng   +4 more
doaj   +1 more source

Isolation of oleanolic acid from Clematis armandii for differentiation it from adulterants by HPTLC/HPLC

open access: yesHeliyon, 2023
Clematis armandii has been used in many Chinese traditional patent medicines all over the world as a form of Caulis Clematidis Armandii. However, it has often been adulterated by Aristolochia manshuriensis, and Iodes vitiginea. A.
Hien Ha Minh   +2 more
doaj   +1 more source

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