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Antibacterial and Antioxidant Activities of Ursolic Acid and Derivatives [PDF]
Molecules, 2014 Ursolic acid, an important bioactive compound, was isolated from ethanol extract of aerial parts of Sambucus australis. In order to develop bioactive ursolic acid derivatives, two semi-synthetic compounds were obtained through modification at C-3.
Patrícia G.G. do Nascimento +7 more
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Co-Amorphous Ursolic Acid–Quercetin Complex Improves Solubility and In Vivo Expectorant–Antitussive Activity [PDF]
PlantsThis study investigated the formation of a co-amorphous complex between ursolic acid and quercetin as a chemically defined model system for improving the formulation performance of a poorly soluble triterpenoid acid. Co-amorphous systems were prepared by
Yuhang Jiang +4 more
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Therapeutic Potential of Ursonic Acid: Comparison with Ursolic Acid [PDF]
Biomolecules, 2020 Plants have been used as drugs to treat human disease for centuries. Ursonic acid (UNA) is a naturally occurring pentacyclic triterpenoid extracted from certain medicinal herbs such as Ziziphus jujuba. Since the pharmacological effects and associated mechanisms of UNA are not well-known, in this work, we attempt to introduce the therapeutic potential ...
Sang Yeol Lee
exaly +4 more sources
Anti-inflammatory and antioxidant activity of ursolic acid: a systematic review and meta-analysis [PDF]
Frontiers in Pharmacology, 2023 Introduction: There is currently evidence suggesting that ursolic acid may exert a favorable influence on both anti-inflammatory and antioxidant impact.
Man Zhao +6 more
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Ursolic Acid and Its Derivatives as Bioactive Agents [PDF]
Molecules, 2019 Non-communicable diseases (NCDs) such as cancer, diabetes, and chronic respiratory and cardiovascular diseases continue to be threatening and deadly to human kind. Resistance to and side effects of known drugs for treatment further increase the threat, while at the same time leaving scientists to search for alternative sources from nature, especially ...
Adebola Omowunmi Oyedeji +2 more
exaly +5 more sources
Ursolic Acid Analogs as Potential Therapeutics for Cancer
Molecules, 2022 Ursolic acid (UA) is a pentacyclic triterpene isolated from a large variety of vegetables, fruits and many traditional medicinal plants. It is a structural isomer of Oleanolic Acid. The medicinal application of UA has been explored extensively over the last two decades.
Bal Lokeshwar Bal L Lokeshwar +2 more
exaly +4 more sources
Applied Food Biotechnology, 2021 Background and Objective: Ursolic acid is a pentacyclic triterpenoid with various biological characteristics. The objective of this study was to investigate potentially biological activities of ursolic acid extracted from apple peels.
Fatemeh Ghasemzadeh +2 more
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Frontiers in Oncology, 2021 Breast cancer remains the most common malignancy and the leading causality of cancer-associated mortality among women worldwide. With proven efficacy, Oldenlandia diffusa has been extensively applied in breast cancer treatment in Traditional Chinese ...
Shengqi Wang +40 more
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Cells, 2022 Cancer is one of the leading causes of death worldwide, thus the search for new cancer therapies is of utmost importance. Ursolic acid is a naturally occurring pentacyclic triterpene with a wide range of pharmacological activities including anti ...
Ditte L. Fogde +9 more
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Foods, 2022 There is limited information on the health effects of apple peel taken from ‘Fuji’ (Malus pumila Mill) apples washed with ozonated water. To clarify the health-promoting effects of peel, the triterpenoids (ursolic acid and oleanolic acid) were quantified
Da-Yeong Ko, Kang-Mo Ku
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