Results 41 to 50 of about 12,996 (224)
AGING MEDICINE, EarlyView.Resistance training combined with ursolic acid supplementation restores anabolic signaling (PI3K/mTORC1) suppressed by diabetes, helping preserve muscle mass. This strategy may offer a potential therapeutic approach to combat muscle atrophy and support healthy aging in diabetic conditions.
Ashkan Sadeghi +4 more
wiley +1 more source
Ursolic Acid Alleviates Orchitis via Modulating Ferroptosis in Peritubular Myoid Cells of Testis
Animal Research and One Health, EarlyView.Ursolic acid modulates key ferroptosis‐related pathways in the peritubular myoid cells of the testis in forest musk deer. ABSTRACT Chronic stress adversely affects reproductive health, increasing susceptibility to pathologies such as orchitis. Additionally, the maintenance of iron homeostasis is essential for preserving the function of the testicles ...
Yang Wang +11 more
wiley +1 more source
Antimicrobial Activity of Oleanolic and Ursolic Acids: An Update [PDF]
Evidence-Based Complementary and Alternative Medicine, 2015 Triterpenoids are the most representative group of phytochemicals, as they comprise more than 20,000 recognized molecules. These compounds are biosynthesized in plants via squalene cyclization, a C30hydrocarbon that is considered to be the precursor of all steroids.
Jesus, Jéssica A. +4 more
openaire +2 more sources
Ursolic Acid Analogs as Potential Therapeutics for Cancer
Molecules, 2022 Ursolic acid (UA) is a pentacyclic triterpene isolated from a large variety of vegetables, fruits and many traditional medicinal plants. It is a structural isomer of Oleanolic Acid. The medicinal application of UA has been explored extensively over the last two decades.
Siva S. Panda +2 more
openaire +3 more sources
Food Chemistry International, EarlyView.Noni seed oil from Morinda citrifolia, highlighting its bioactive composition, conventional and green extraction methods, and major stability challenges. Encapsulation strategies improve oxidative stability and bioavailability, along with potential applications in functional foods and cosmetics, and key barriers to large‐scale commercialization ...
Sumidha Palanisamy +4 more
wiley +1 more source
Ursolic acid (3β-hydroxy-urs- 12-en-28-oic acid).
, 2018 Ursolic acid (3β-hydroxy-urs- 12-en-28-oic acid).
Mohammed F. Abuzinadah (4984400) +4 more
core +1 more source
Effect of ursolic acid on olanzapine induced weight gain in Sprague Dawley rats [PDF]
, 2020 760-769Antipsychotics used in the treatment of schizophrenia are known to cause weight gain. Phytoconstituents are used to manage such drug-induced weight gain.
Zhen, Khor Ming +10 more
core +1 more source
Ursolic Acid and Its Derivatives as Bioactive Agents [PDF]
Molecules, 2019 Non-communicable diseases (NCDs) such as cancer, diabetes, and chronic respiratory and cardiovascular diseases continue to be threatening and deadly to human kind. Resistance to and side effects of known drugs for treatment further increase the threat, while at the same time leaving scientists to search for alternative sources from nature, especially ...
Sithenkosi Mlala +3 more
openaire +4 more sources
iNew Medicine, EarlyView.Natural products and traditional Chinese medicine target metabolic pathways underlying right ventricular dysfunction in pulmonary arterial hypertension. Integrating multi‐omics, artificial intelligence, and systems biology may enable precision cardiometabolic therapies to restore right ventricular metabolism and improve clinical outcomes.
Yihao Wu, Zhehui Tang, Hongwei Yao
wiley +1 more source
Journal of the Science of Food and Agriculture, EarlyView.Abstract BACKGROUND The present study aimed to valorize broccoli by‐products (leaves and stems) through the extraction of bioactive compounds using supercritical fluid extraction (SFE). The influence of broccoli variety, plant part and maturation stage on total phenolic content (TPC), antioxidant activity and antimicrobial properties was evaluated ...
Iris Gudiño +5 more
wiley +1 more source