Results 41 to 50 of about 2,518,282 (213)
Ursolic Acid as a Trypanocidal Constituent in Rosemary.
Biological and Pharmaceutical Bulletin, 2002 The MeOH extract of the leaves of rosemary (Rosmarinus officinalis L.) completely inhibited the motility of cultured epimastigotes of Trypanosoma cruzi at the concentration of 2 mg/ml after 2 h of incubation. Activity-guided fractionation of the MeOH extract has resulted in the isolation of three triterpene acids, betulinic, oleanolic and ursolic acids.
Abe, Fumiko +6 more
openaire +3 more sources
Plant‐Derived Natural Product Nanodelivery System in Cancer Therapy
Phytotherapy Research, EarlyView.This review comprehensively summarizes the recent progress and emerging concepts in nanotechnology‐based delivery systems for plant‐derived natural products, with a particular focus on their application in precision cancer therapy. ABSTRACT Plant‐derived natural products have emerged as important sources of anticancer agents because of their diverse ...
Changqi Shi +9 more
wiley +1 more source
Estudo do efeito e do mecanismo de ação de triterpenos naturais e da 1,25 (OH)2 vitamina D3 na homeostasia da glicose: papel destes compostos como secretagogos de insulina e/ou insulinomiméticos [PDF]
, 2015 Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas, Programa de Pós-Graduação em Bioquímica, Florianópolis, 2015.A hiperglicemia crônica proveniente da diminuição da produção insulínica e do aumento da resistência ...
Castro, Allisson Jhonatan Gomes
core
Herbal Therapeutics in Osteoporosis: Mechanisms, Evidence, and Translational Potential
Phytotherapy Research, EarlyView.Schematic overview of bone remodeling dysregulation in osteoporosis and the multi‐target protective role of herbal therapeutics. ABSTRACT Osteoporosis is a chronic bone disease marked by reduced density and increased fracture risk. Current treatments face limitations in safety, efficacy, and long‐term adherence, prompting interest in alternative ...
Elnaz Vafadar Moradi +5 more
wiley +1 more source
Ursolic acid (3β-hydroxy-urs- 12-en-28-oic acid).
, 2018 Ursolic acid (3β-hydroxy-urs- 12-en-28-oic acid).
Mohammed F. Abuzinadah (4984400) +4 more
core +1 more source
Smart Molecules, EarlyView.An AI‐driven framework integrating disease‐network analysis, direction‐aware molecular screening, and carrier‐free co‐assembly engineering enables nanomedicine design. The dual‐constraint deep learning model predicts API–target affinity and regulatory direction to prioritize complementary APIs.
Kai Xiao +14 more
wiley +1 more source
Smart Molecules, EarlyView.Smart mesoporous silica nanoparticles integrate tunable pore structures, molecular gates, targeting ligands, and stimuli‐responsive components to achieve controlled drug release for precision cancer therapy. This review highlights design principles, therapeutic applications, and future directions in immunotherapy, biodegradability, biosafety, and ...
Majdi Al‐Amili, Lei Lei, Zhu Jin
wiley +1 more source
Therapeutic potential of natural products in cancer immunotherapy: Advances and challenges
British Journal of Pharmacology, EarlyView.This review systematically outlines the mechanisms underlying tumour immunotherapy resistance and elucidates the role of natural products in enhancing therapeutic efficacy as immunomodulatory adjuvants. Abstract Immunotherapy has emerged as a clinically pivotal approach in cancer treatment, but its application remains limited to a small subset of ...
Rao Hu +6 more
wiley +1 more source
Efeito tipo-antidepressivo e tipo-ansiolítico do ácido ursólico em camundongos em diferentes modelos animais [PDF]
, 2015 Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas, Programa de Pós-Graduação em Neurociências, Florianópolis, 2015.A depressão é uma doença crônica e recorrente, altamente prevalente e responsável por considerável ...
Colla, André Roberto da Silva
core
2D structure of Ursolic Acid (UA).
, 2014 2D structure of Ursolic Acid (UA).
P. K. Murthy (191191) +7 more
core +1 more source