Results 21 to 30 of about 2,518,282 (213)

Determination of ursolic acid and ursolic acid lactone in the leaves of Eucalyptus tereticornis by HPLC [PDF]

open access: yesJournal of the Brazilian Chemical Society, 2012
A simple isocratic HPLC method has been developed for the simultaneous quantification of two bioactive triterpenes, ursolic acid and ursolic acid lactone in E. tereticornis leaves. Samples were analyzed on RP-18 (4.6 × 250 mm, 5 µm) column with methanol and water acidified to pH 3.5 with TFA (88:12) at 210 nm.
Maurya, Anupam   +1 more
openaire   +3 more sources

Mechanism of Action of Ursolic Acid in Ameliorating Mitochondrial Dysfunction in Podocytes Induced by High Glucose [PDF]

open access: yesShipin Kexue
Objective: This study aimed to investigate the protective effects of ursolic acid on mitochondrial dysfunction in podocytes induced by high glucose and to explore the underlying mechanism.
GU Huixian, AYIXIAMU·Maitituoheti, WU Siyu, JIANG Xianglong, YAO Lan
doaj   +1 more source

The Metabolic Changes of Artesunate and Ursolic Acid on Syrian Golden Hamsters Fed with the High-Fat Diet

open access: yesMolecules, 2020
Artesunate was well known as an antimalarial drug. Our previous research found that it has hypolipidemia effects in rabbits fed with a high-fat diet, especially combined with ursolic acid.
Shichen Pu   +6 more
doaj   +1 more source

TRITERPENOIDS AND FLAVONOIDAL GLYCOSIDE FROM FRUITS OF SORBUS AUCUPARIA (DC) CULTIVATED IN EGYPT [PDF]

open access: yesBulletin of Pharmaceutical Sciences. Assiut University, 1997
From the chloroform soluble fraction of ethanolic extract of the dried fruits of Sorbus aucuparia (DC)four triterpenes were isolated and identified as a-amyrin, ursolic acid, methyl 2a-hydroxy ursolate, 2a-hydroxy ursolic acid in addition to b-sitosterol.
S. Youssef
doaj   +1 more source

Ursolic acid in health and disease

open access: yesThe Korean Journal of Physiology & Pharmacology, 2018
Ursolic acid (UA) is a natural triterpene compound found in various fruits and vegetables. There is a growing interest in UA because of its beneficial effects, which include anti-inflammatory, anti-oxidant, anti-apoptotic, and anti-carcinogenic effects.
Seo, Dae Yun   +7 more
openaire   +2 more sources

Therapeutic potentials of Crataegus azarolus var. eu- azarolus Maire leaves and its isolated compounds

open access: yesBMC Complementary and Alternative Medicine, 2017
Background Hyperglycemia is a complicated condition accompanied with high incidence of infection and dyslipidemia. This study aimed to explore the phyto-constituents of Crataegus azarolus var.
Eman Abu-Gharbieh, Naglaa Gamil Shehab
doaj   +1 more source

Enhancement of Platelet Aggregation by Ursolic Acid and Oleanolic Acid [PDF]

open access: yesBiomolecules & Therapeutics, 2014
The pentacyclic triterpenoid ursolic acid (UA) and its isomer oleanolic acid (OA) are ubiquitous in food and plant medicine, and thus are easily exposed to the population through natural contact or intentional use. Although they have diverse health benefits, reported cardiovascular protective activity is contentious. In this study, the effect of UA and
Kim, Mikyung   +2 more
openaire   +2 more sources

Ursolic acid inhibits superoxide production in activated neutrophils and attenuates trauma-hemorrhage shock-induced organ injury in rats.

open access: yesPLoS ONE, 2014
Neutrophil activation is associated with the development of organ injury after trauma-hemorrhagic shock. In the present study, ursolic acid inhibited the superoxide anion generation and elastase release in human neutrophils.
Tsong-Long Hwang   +6 more
doaj   +1 more source

Regulation of mitogen-activated protein kinase signaling pathway and proinflammatory cytokines by ursolic acid in murine macrophages infected with Mycobacterium avium

open access: yesInfectious Disease Reports, 2020
Mycobacterium avium, one of the closest relatives of Mycobacterium tuberculosis (MTB), offers an advantage in studying MTB because of its tuberculosis-like effect in humans and host immune tolerance.
Dian Ayu Eka Pitaloka   +4 more
doaj   +1 more source

Anxiolytic-like effects of ursolic acid in mice [PDF]

open access: yes, 2015
Ursolic acid is a pentacyclic triterpenoid that possesses several biological and neuropharmacological effects including antidepressant-like activity. Anxiety disorders represent common and disability psychiatric conditions that are often associated with ...
Rodrigues, Ana Lúcia S.   +3 more
core   +1 more source

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