Results 11 to 20 of about 10,207 (185)
Molecules, 2016 (1) Background: Several triterpenoids were found to act synergistically with classes of antibiotic, indicating that plant-derived chemicals have potential to be used as therapeutics to enhance the activity of antibiotics against multidrug-resistant ...
Chao-Min Wang +3 more
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Antibacterial compounds of the cultivated Robusta coffee: Coffea canephora Pierre ex A. Froehner
Scientific African, 2022 The stems and leaves of robusta coffee, Coffea canephora Pierre ex A. Froehner, one of the traded Coffea species, yielded caffeine (1), lupeol (2), ursolic acid (3), 3β-acetyl oleanolic acid (4), friedelin (5), asperphernamate (6), squalene (7 ...
S.G. Mewaba +11 more
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Therapeutic Potential of Ursonic Acid: Comparison with Ursolic Acid [PDF]
Biomolecules, 2020 Plants have been used as drugs to treat human disease for centuries. Ursonic acid (UNA) is a naturally occurring pentacyclic triterpenoid extracted from certain medicinal herbs such as Ziziphus jujuba. Since the pharmacological effects and associated mechanisms of UNA are not well-known, in this work, we attempt to introduce the therapeutic potential ...
Juhyeon Son, Sang Yeol Lee
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Evaluation of Anti-Toxoplasma gondii Effect of Ursolic Acid as a Novel Toxoplasmosis Inhibitor
Pharmaceuticals, 2018 This study was carried out to evaluate the anti-parasitic effect of ursolic acid against Toxoplasma gondii (T. gondii) that induces toxoplasmosis, particularly in humans. The anti-parasitic effects of ursolic acid against T.
Won Hyung Choi, In Ah Lee
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PLoS ONE, 2012 Skeletal muscle Akt activity stimulates muscle growth and imparts resistance to obesity, glucose intolerance and fatty liver disease. We recently found that ursolic acid increases skeletal muscle Akt activity and stimulates muscle growth in non-obese ...
Steven D Kunkel +7 more
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Ursolic acid inhibits colistin efflux and curtails colistin resistant Enterobacteriaceae
AMB Express, 2019 Colistin resistance in Enterobacteriaceae especially Klebsiella pneumoniae and Escherichia coli is driving the evolution of pan drug resistant strains.
Niranjana Sri Sundaramoorthy +6 more
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Determination of ursolic acid and ursolic acid lactone in the leaves of Eucalyptus tereticornis by HPLC [PDF]
Journal of the Brazilian Chemical Society, 2012 A simple isocratic HPLC method has been developed for the simultaneous quantification of two bioactive triterpenes, ursolic acid and ursolic acid lactone in E. tereticornis leaves. Samples were analyzed on RP-18 (4.6 × 250 mm, 5 µm) column with methanol and water acidified to pH 3.5 with TFA (88:12) at 210 nm.
Maurya, Anupam +1 more
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Antiangiogenic Activity of Ursolic Acid
Integrative Cancer Therapies, 2010 Angiogenesis, the formation of new capillaries from preexisting vessels, is essential for tumor progression. Ursolic acid inhibited the tumor-associated capillary formation in C57BL/6 mice induced by highly metastatic B16F-10 melanoma cells.
Manu, Kanjoormana, Girija, Kuttan
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Mechanism of Action of Ursolic Acid in Ameliorating Mitochondrial Dysfunction in Podocytes Induced by High Glucose [PDF]
Shipin KexueObjective: This study aimed to investigate the protective effects of ursolic acid on mitochondrial dysfunction in podocytes induced by high glucose and to explore the underlying mechanism.
GU Huixian, AYIXIAMU·Maitituoheti, WU Siyu, JIANG Xianglong, YAO Lan
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TRITERPENOIDS AND FLAVONOIDAL GLYCOSIDE FROM FRUITS OF SORBUS AUCUPARIA (DC) CULTIVATED IN EGYPT [PDF]
Bulletin of Pharmaceutical Sciences. Assiut University, 1997 From the chloroform soluble fraction of ethanolic extract of the dried fruits of Sorbus aucuparia (DC)four triterpenes were isolated and identified as a-amyrin, ursolic acid, methyl 2a-hydroxy ursolate, 2a-hydroxy ursolic acid in addition to b-sitosterol.
S. Youssef
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