Results 11 to 20 of about 2,518,282 (213)

Antiangiogenic Activity of Ursolic Acid

Integrative Cancer Therapies, 2010
Angiogenesis, the formation of new capillaries from preexisting vessels, is essential for tumor progression. Ursolic acid inhibited the tumor-associated capillary formation in C57BL/6 mice induced by highly metastatic B16F-10 melanoma cells.
Manu, Kanjoormana, Girija, Kuttan
core   +4 more sources

Ursolic acid inhibits colistin efflux and curtails colistin resistant Enterobacteriaceae [PDF]

AMB Express, 2019
Colistin resistance in Enterobacteriaceae especially Klebsiella pneumoniae and Escherichia coli is driving the evolution of pan drug resistant strains.
Niranjana Sri Sundaramoorthy, Harihar M. Mohan, Shankar Subramaniam, Thiagarajan Raman, Subramaniapillai Selva Ganesan, Aravind Sivasubamanian, Saisubramanian Nagarajan   +6 more
doaj   +2 more sources

Ursolic acid: an overview including research performed in Peru [PDF]

Revista Bases de la Ciencia, 2021
  Ursolic acid (3β-3-hydroxy-urs-12-en-28-oic-acid) is a pentacyclic triterpenoid compound present in many medicinal herbs and edible fruits of different species of plants.
Michael Azael Ludeña Huaman, Reneé Isabel Huamán Quispe, Ana Luz Tupa Quispe, Carlos Alberto Serrano Flores   +3 more
doaj   +2 more sources

Evaluation of Anti-Toxoplasma gondii Effect of Ursolic Acid as a Novel Toxoplasmosis Inhibitor

Pharmaceuticals, 2018
This study was carried out to evaluate the anti-parasitic effect of ursolic acid against Toxoplasma gondii (T. gondii) that induces toxoplasmosis, particularly in humans. The anti-parasitic effects of ursolic acid against T.
Won Hyung Choi, In Ah Lee
doaj   +2 more sources

The Pleiotropic Antibacterial Mechanisms of Ursolic Acid against Methicillin-Resistant Staphylococcus aureus (MRSA)

Molecules, 2016
(1) Background: Several triterpenoids were found to act synergistically with classes of antibiotic, indicating that plant-derived chemicals have potential to be used as therapeutics to enhance the activity of antibiotics against multidrug-resistant ...
Chao-Min Wang, Yun-Lian Jhan, Shang-Jie Tsai, Chang-Hung Chou   +3 more
doaj   +2 more sources

Ursolic acid increases skeletal muscle and brown fat and decreases diet-induced obesity, glucose intolerance and fatty liver disease.

PLoS ONE, 2012
Skeletal muscle Akt activity stimulates muscle growth and imparts resistance to obesity, glucose intolerance and fatty liver disease. We recently found that ursolic acid increases skeletal muscle Akt activity and stimulates muscle growth in non-obese ...
Steven D Kunkel, Christopher J Elmore, Kale S Bongers, Scott M Ebert, Daniel K Fox, Michael C Dyle, Steven A Bullard, Christopher M Adams   +7 more
doaj   +2 more sources

Ursolic Acid Targets Glucosyltransferase and Inhibits Its Activity to Prevent Streptococcus mutans Biofilm Formation

Frontiers in Microbiology, 2021
Streptococcus mutans (S. mutans), the prime pathogen of dental caries, can secrete glucosyltransferases (GTFs) to synthesize extracellular polysaccharides (EPSs), which are the virulence determinants of cariogenic biofilms.
Yucui Liu, Yucui Liu, Yanxin Huang, Cong Fan, Cong Fan, Zhongmei Chi, Miao Bai, Luguo Sun, Li Yang, Chunlei Yu, Zhenbo Song, Xiaoguang Yang, Xiaoguang Yang, Jingwen Yi, Jingwen Yi, Shuyue Wang, Lei Liu, Guannan Wang, Lihua Zheng   +18 more
doaj   +1 more source

Ursolic acid, a natural pentacyclic triterpenoid, inhibits intracellular trafficking of proteins and induces accumulation of intercellular adhesion molecule-1 linked to high-mannose-type glycans in the endoplasmic reticulum

FEBS Open Bio, 2014
Ursolic acid (3β-hydroxy-urs-12-en-28-oic acid) is a natural pentacyclic triterpenoid that is present in many plants, including medicinal herbs, and foods.
Satoshi Mitsuda, Tomonobu Yokomichi, Junpei Yokoigawa, Takao Kataoka   +3 more
doaj   +1 more source

Ursolic Acid Inhibits Na+/K+-ATPase Activity and Prevents TNF-α-Induced Gene Expression by Blocking Amino Acid Transport and Cellular Protein Synthesis

Biomolecules, 2011
Pro-inflammatory cytokines, such as tumor necrosis factor (TNF)-α, induce the expression of a wide variety of genes, including intercellular adhesion molecule-1 (ICAM-1).
Takao Kataoka, Masayoshi Ando, Shigeru Taketani, Liwei Fu, Yuriko Yamada, Nana Oshima, Tomonobu Yokomichi, Kyoko Morimoto   +7 more
doaj   +1 more source

Antibacterial compounds of the cultivated Robusta coffee: Coffea canephora Pierre ex A. Froehner

Scientific African, 2022
The stems and leaves of robusta coffee, Coffea canephora Pierre ex A. Froehner, one of the traded Coffea species, yielded caffeine (1), lupeol (2), ursolic acid (3), 3β-acetyl oleanolic acid (4), friedelin (5), asperphernamate (6), squalene (7 ...
S.G. Mewaba, E.N. Happi, B.M.N. Nangmou, M.K. Langat, H. Siddique, N. Sadgrove, A.F.W. Kamdem, J.C. Vardamides, E. Mas-Claret, S.M. Isyaka, W. Rotich, B.G.A. Azebaze   +11 more
doaj   +1 more source