Results 11 to 20 of about 12,996 (224)
Evaluation of Anti-Toxoplasma gondii Effect of Ursolic Acid as a Novel Toxoplasmosis Inhibitor
Pharmaceuticals, 2018 This study was carried out to evaluate the anti-parasitic effect of ursolic acid against Toxoplasma gondii (T. gondii) that induces toxoplasmosis, particularly in humans. The anti-parasitic effects of ursolic acid against T.
Won Hyung Choi, In Ah Lee
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Ursolic Acid Impairs Cellular Lipid Homeostasis and Lysosomal Membrane Integrity in Breast Carcinoma Cells [PDF]
Cells, 2022 Cancer is one of the leading causes of death worldwide, thus the search for new cancer therapies is of utmost importance. Ursolic acid is a naturally occurring pentacyclic triterpene with a wide range of pharmacological activities including anti ...
Ditte L. Fogde +9 more
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PLoS ONE, 2012 Skeletal muscle Akt activity stimulates muscle growth and imparts resistance to obesity, glucose intolerance and fatty liver disease. We recently found that ursolic acid increases skeletal muscle Akt activity and stimulates muscle growth in non-obese ...
Steven D Kunkel +7 more
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Anxiolytic-like effects of ursolic acid in mice
European Journal of Pharmacology, 2015 Ursolic acid is a pentacyclic triterpenoid that possesses several biological and neuropharmacological effects including antidepressant-like activity. Anxiety disorders represent common and disability psychiatric conditions that are often associated with depressive symptoms.
Colla, André R.S. +3 more
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PLoS ONE, 2014 Neutrophil activation is associated with the development of organ injury after trauma-hemorrhagic shock. In the present study, ursolic acid inhibited the superoxide anion generation and elastase release in human neutrophils.
Tsong-Long Hwang +6 more
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Applied Food Biotechnology, 2021 Background and Objective: Ursolic acid is a pentacyclic triterpenoid with various biological characteristics. The objective of this study was to investigate potentially biological activities of ursolic acid extracted from apple peels.
Fatemeh Ghasemzadeh +2 more
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Frontiers in Oncology, 2021 Breast cancer remains the most common malignancy and the leading causality of cancer-associated mortality among women worldwide. With proven efficacy, Oldenlandia diffusa has been extensively applied in breast cancer treatment in Traditional Chinese ...
Shengqi Wang +40 more
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Foods, 2022 There is limited information on the health effects of apple peel taken from ‘Fuji’ (Malus pumila Mill) apples washed with ozonated water. To clarify the health-promoting effects of peel, the triterpenoids (ursolic acid and oleanolic acid) were quantified
Da-Yeong Ko, Kang-Mo Ku
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Frontiers in Microbiology, 2021 Streptococcus mutans (S. mutans), the prime pathogen of dental caries, can secrete glucosyltransferases (GTFs) to synthesize extracellular polysaccharides (EPSs), which are the virulence determinants of cariogenic biofilms.
Yucui Liu +18 more
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Therapeutic Potential of Ursonic Acid: Comparison with Ursolic Acid [PDF]
Biomolecules, 2020 Plants have been used as drugs to treat human disease for centuries. Ursonic acid (UNA) is a naturally occurring pentacyclic triterpenoid extracted from certain medicinal herbs such as Ziziphus jujuba. Since the pharmacological effects and associated mechanisms of UNA are not well-known, in this work, we attempt to introduce the therapeutic potential ...
Juhyeon Son, Sang Yeol Lee
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