Results 51 to 60 of about 12,996 (224)
Estudo do efeito e do mecanismo de ação de triterpenos naturais e da 1,25 (OH)2 vitamina D3 na homeostasia da glicose: papel destes compostos como secretagogos de insulina e/ou insulinomiméticos [PDF]
, 2015 Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas, Programa de Pós-Graduação em Bioquímica, Florianópolis, 2015.A hiperglicemia crônica proveniente da diminuição da produção insulínica e do aumento da resistência ...
Castro, Allisson Jhonatan Gomes
core
2D structure of Ursolic Acid (UA).
, 2014 2D structure of Ursolic Acid (UA).
P. K. Murthy (191191) +7 more
core +1 more source
Neuroprotective effects of ursodeoxycholic acid in Parkinson's disease and Alzheimer's disease
Neuroprotection, EarlyView.In Parkinson's disease (PD) and Alzheimer's disease (AD), various shared pathological mechanisms exist. UDCA has been shown to exert neuroprotective effects in preclinical and clinical studies. Such effects include the mitigation of neuroinflammation as well as rescue effects on mitochondrial dysfunction, oxidative stress, impaired autophagy, and ...
Ashley En Yi Chong +3 more
wiley +1 more source
Efeito tipo-antidepressivo e tipo-ansiolítico do ácido ursólico em camundongos em diferentes modelos animais [PDF]
, 2015 Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas, Programa de Pós-Graduação em Neurociências, Florianópolis, 2015.A depressão é uma doença crônica e recorrente, altamente prevalente e responsável por considerável ...
Colla, André Roberto da Silva
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Ursolic acid prevents cyclophosphamide induced myocardial oxidative tissue damage in wistar rats [PDF]
, 2020 525-532Herbs and spices of natural origin have been used traditionally for culinary and therapeutic purposes. Ursolic acid, a pentacyclic triterpenoid, is a major component of various foods, herbs and spices utilized in daily life.
Joshi, Viraj +3 more
core +3 more sources
Antagonistic effect of ursolic acid on Staphylococcal biofilms [PDF]
Veterinary World, 2018 The present study was carried out to study the effect of ursolic acid (UA) as a potential anti-biofilm agent in dispersing the biofilm generated by Staphylococcus aureus isolated from milk samples of crossbred dairy cows on the day of drying. Further, in the S.
J. Shiva Jyothi +4 more
openaire +3 more sources
Natural Products as Modulators of ABC Transporters in Breast Cancer
Phytotherapy Research, EarlyView.ABSTRACT Breast cancer remains a significant global health challenge, with high incidence and mortality rates despite advancements in early detection and treatment. Multidrug resistance (MDR), particularly in aggressive subtypes like triple‐negative breast cancer (TNBC), continues to hinder effective therapy.
Yoganishalini Sagadevan +2 more
wiley +1 more source
Pathogens, 2019 This study was performed to investigate the mechanism of action of ursolic acid in terms of anti-Toxoplasma gondii effects, including immunomodulatory effects. We evaluated the anti-T. gondii effects of ursolic acid, and analyzed the production of nitric
Won Hyung Choi, In Ah Lee
doaj +1 more source
Frontiers in Cellular and Infection Microbiology, 2023 BackgroundAntimicrobial resistance is a serious threat to public health globally. It is a slower-moving pandemic than COVID-19, so we are fast running out of treatment options.PurposeThus, this study was designed to search for an alternative biomaterial ...
Rewan Abdelaziz +6 more
doaj +1 more source
Therapeutic potential of natural products in cancer immunotherapy: Advances and challenges
British Journal of Pharmacology, EarlyView.This review systematically outlines the mechanisms underlying tumour immunotherapy resistance and elucidates the role of natural products in enhancing therapeutic efficacy as immunomodulatory adjuvants. Abstract Immunotherapy has emerged as a clinically pivotal approach in cancer treatment, but its application remains limited to a small subset of ...
Rao Hu +6 more
wiley +1 more source