Results 51 to 60 of about 11,485 (176)

Isolation and Quantificative Analysis of Oleanolic Acid from Satureja mutica Fisch. & C. A. Mey.

Journal of Medicinal Plants, 2009
Background: Satureja mutica (Lamiaceae) is an herbaceous plant which grows in North-West of Iran. Oleanolic acid has been previously isolated from some Lamiaceae genus and showed a broad range of biological activities.
AR Gohari, S Saeidnia, A Hadjiakhoondi, M Abdoullahi, M Nezafati   +4 more
doaj  

Effects of Oleanolic Acid Derived from Wine Pomace on Periodontopathic Bacterial Growth in Healthy Individuals: A Randomized Placebo-Controlled Study

Dentistry Journal
Periodontal disease is caused by oral pathogenic bacteria and is associated with systemic disease and frailty. Therefore, its prevention is crucial in extending healthy life expectancy.
Kyoko Shimazu, Kouta Ookoshi, Satoshi Fukumitsu, Hiroyuki Kagami, Chieko Mitsuhata, Ryota Nomura, Kazuhiko Aida   +6 more
doaj   +1 more source

A Comprehensive Review on Nutrition, Phytochemistry, Pharmacology and Food Application Perspectives of Bioactive Rich Superfruits

Future Postharvest and Food, Volume 3, Issue 2, Page 163-184, June 2026.
The review critically evaluated and compared the selected superfruit phytochemistry, their bioactive composition and the key health benefits majorly emphasizing the antioxidant potential. It has highlighted the translational challenges in formulating functional foods by addressing the issues related to delivery system, bioavailability mechanism and the
Sharath Kumar Nagaraja, Javid Iqbal Mir, Mahendra Kumar Verma, Aamir Hussain Dar   +3 more
wiley   +1 more source

The Chemical Structures, Neuroprotective Effects, Structure–Activity Relationships, and Applications of Flavonoids, Phenolic Acids, Terpenoids, and Sterols in Dandelion: A Review

Food Science &Nutrition, Volume 14, Issue 6, June 2026.
This review systematically summarizes the chemical structures and structure–activity relationships of key bioactive compounds in dandelion, including flavonoids, phenolic acids, terpenoids, and sterols. It highlights their neuroprotective mechanisms against neuroinflammation and oxidative stress, while outlining their promising dual applications in the
Hongye Li, Bingchan Qu, Jiasu Wu, Menghan Sun, Youlin Xue, Tiejing Li, Chang Tan, Shan Wang, Chong Ning, Chongting Guo   +9 more
wiley   +1 more source

Semisynthesis of Derivatives of Oleanolic Acid from Syzygium aromaticum and Their Antinociceptive and Anti-Inflammatory Properties

Mediators of Inflammation, 2016
Oleanolic acid is a pentacyclic triterpenoid compound widely found in plants and well known for its medicinal properties. Oleanolic acid (OA) was isolated from the ethyl acetate extract of Syzygium aromaticum flower buds.
Sibusiso Rali, Opeoluwa O. Oyedeji, Olukayode O. Aremu, Adebola O. Oyedeji, Benedicta N. Nkeh-Chungag   +4 more
doaj   +1 more source

RTA‐408 Enhances Radiosensitivity and Inhibited Tumor Progression via JNK Pathway in Glioblastoma

The Kaohsiung Journal of Medical Sciences, Volume 42, Issue 6, June 2026.
ABSTRACT Glioblastoma (GBM) is an aggressive brain tumor with poor prognosis owing to its high invasiveness and resistance to therapy. RTA‐408, a synthetic triterpenoid and nuclear factor erythroid 2‐related factor 2 activator, exhibits anti‐inflammatory and anti‐cancer properties; however, its effects on GBM remain unclear. This study investigated the
Hung‐Pei Tsai, Hao Qin, Yoon Bin Chong, I‐Hsiang Chen, Shih‐Hsun Kuo, Tzu‐Ting Tseng, Ann‐Shung Lieu   +6 more
wiley   +1 more source

Inhibition of key enzymes linked to type 2 diabetes by compounds isolated from Aframomum melegueta fruit

Pharmaceutical Biology, 2017
Context: The use of Aframomum melegueta K. Schum. (Zingiberaceae) fruit for treatment of diabetes has recently been established in Nigeria. However, compounds responsible for the antidiabetic action have not been identified.
Aminu Mohammed, Victoria Awolola Gbonjubola, Neil Anthony Koorbanally, Md. Shahidul Islam   +3 more
doaj   +1 more source

Nanoencapsulation of Essential Oils: A Review of Current Trends and Advances in Preparation, Characterization, and Biomedical Applications

Nano Select, Volume 7, Issue 6, June 2026.
This review highlights nanoencapsulation as a powerful strategy to improve the stability, solubility, and bioavailability of essential oils. It surveys key EO‐producing plant families, major bioactive constituents, and therapeutic properties, alongside high‐ and low‐energy nanoformulation methods. Applications across pharmaceutical, cosmetic, food, and
Mateusz Guz, Awatif Belkhiri‐Baines, Krzysztof Szczepanowicz, Anna Trybala   +3 more
wiley   +1 more source

Preparation, characterization, and in vivo pharmacokinetics of nanostructured lipid carriers loaded with oleanolic acid and gentiopicrin

International Journal of Nanomedicine, 2013
Kunchi Zhang, Shaowa Lv, Xiuyan Li, Yufei Feng, Xin Li, Lu Liu, Shuang Li, Yongji Li School of Pharmacy, Heilongjiang University of Traditional Chinese Medicine, Harbin, Heilongjiang Province, People’s Republic of China Background: The purpose of ...
Zhang KC, Lv SW, Li XY, Feng YF, Li X, Liu L, Li S, Li YJ   +7 more
doaj  

Allosterically activating SHP2 by oleanolic acid inhibits STAT3–Th17 axis for ameliorating colitis

Acta Pharmaceutica Sinica B
Src homology 2 domain-containing tyrosine phosphatase 2 (SHP2) is an essential tyrosine phosphatase that is pivotal in regulating various cellular signaling pathways such as cell growth, differentiation, and survival.
Jinbo Hu, Wen Liu, Yi Zou, Chenyang Jiao, Jiazhen Zhu, Qiang Xu, Jianjun Zou, Yang Sun, Wenjie Guo   +8 more
doaj   +1 more source