Results 61 to 70 of about 11,485 (176)

Liquid Chromatography‐Electrospray Ionization‐Tandem Mass Spectrometry Profiling, Antioxidant, Antibacterial, and Antidiabetic Properties of Fagonia cretica L.: Insights From In Vitro and In Silico Approaches

open access: yesChemistryOpen, Volume 15, Issue 6, June 2026.
Fagonia cretica L.: Phytochemical investigation and exploration of bioactivity through in vitro and in silico approaches. This study provides an integrative evaluation of the aqueous extract of Fagonia cretica L., a species long employed in traditional medicine but insufficiently characterized through systematic experimental and computational ...
Neghmouche Nacer Salah   +8 more
wiley   +1 more source

Oleanolic Acid Promotes the Formation of Probiotic Escherichia coli Nissle 1917 (EcN) Biofilm by Inhibiting Bacterial Motility

open access: yesMicroorganisms
Probiotic biofilms have been beneficial in the fight against infections, restoring the equilibrium of the host’s gut microbiota, and enhancing host health. They are considered a novel strategy for probiotic gut colonization.
Dan Liu   +9 more
doaj   +1 more source

Analysis of BpbHLH Gene Family Responsive to MeJA Signalling in Betula platyphylla Suk. and Functional Mechanisms of BpbHLH42/44 in Genetic Improvement and Triterpenoid Biosynthesis

open access: yesPlant Biotechnology Journal, Volume 24, Issue 6, Page 4342-4357, June 2026.
ABSTRACT The basic helix–loop–helix (bHLH) transcription factor family regulates plant secondary metabolism, development and stress responses. Although triterpenoids such as betulinic acid (BA), betulin (BT) and oleanolic acid (OA) from Betula platyphylla Suk.
Ying Li   +9 more
wiley   +1 more source

Oleanolic acid liposomes with polyethylene glycol modification: promising antitumor drug delivery

open access: yesInternational Journal of Nanomedicine, 2012
Dawei Gao, Shengnan Tang, Qi TongApplied Chemical Key Laboratory of Hebei Province, College of Environmental and Chemical Engineering, Yanshan University, Qinhuangdao, ChinaBackground: Oleanolic acid is a pentacyclic triterpene present in many fruits and
Gao D, Tang S, Tong Q
doaj  

Oleanolic acid combined with aspirin plays antitumor roles in colorectal cancer via the Akt/NFκB/IκBα/COX2 pathway. [PDF]

open access: yesCell Death Discov
Among the common malignancies, colorectal cancer (CRC) is often resistant to chemotherapy because of drug resistance and severe toxicity. Currently, aspirin is one of the most promising CRC chemopreventive drugs, both for primary prevention and for ...
Zhou Y   +5 more
europepmc   +2 more sources

Design and Synthesis of New Anticancer Glycyrrhetinic Acids and Oleanolic Acids

open access: yesBiological & Pharmaceutical Bulletin, 2017
A series of new glycyrrhetinic acids and oleanolic acids has been designed and synthesized based on the principles of combinatorial chemical synthesis. Their anticancer activities were further studied by using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) method with hepatocellular carcinoma (Hep-G2), breast cancer (MCF-7) cell ...
Wang, Rui   +5 more
openaire   +3 more sources

Efficient oxidation of oleanolic acid derivatives using magnesium bis(monoperoxyphthalate) hexahydrate (MMPP): A convenient 2-step procedure towards 12-oxo-28-carboxylic acid derivatives

open access: yesBeilstein Journal of Organic Chemistry, 2012
A new, straightforward and high yielding procedure to convert oleanolic acid derivatives into the corresponding δ-hydroxy-γ-lactones, by using the convenient oxidizing agent magnesium bis(monoperoxyphthalate) hexahydrate (MMPP) in refluxing acetonitrile,
Jorge A. R. Salvador   +4 more
doaj   +1 more source

A Comparative Analysis of Ursolic and Oleanolic Acids in Eleven Epilobium Species

open access: yesMolecules
A comparative analysis of pentacyclic triterpenoids (ursolic acid and oleanolic acid) in the aerial parts of eleven Epilobium species was performed using high-performance liquid chromatography (HPLC) results.
Kateryna Uminska   +7 more
doaj   +1 more source

Ursolic and Oleanolic Acids Induce Mitophagy in A549 Human Lung Cancer Cells

open access: yesMolecules, 2019
Ursolic and oleanolic acids are natural isomeric triterpenes known for their anticancer activity. Here, we investigated the effect of triterpenes on the viability of A549 human lung cancer cells and the role of autophagy in their activity.
Nayeli Shantal Castrejón-Jiménez   +12 more
doaj   +1 more source

Role of Modifier in Microwave Assisted Extraction of Oleanolic Acid from : Application of Green Extraction Technology for Botanicals

open access: yesNatural Product Communications, 2009
This work highlights the development of a green extraction technology for botanicals with the use of microwave energy. Taking into consideration the extensive time involved in conventional extraction methods, coupled with usage of large volumes of ...
Vivekananda Mandal   +2 more
doaj   +1 more source

Home - About - Disclaimer - Privacy