Results 81 to 90 of about 2,519,723 (219)

Oleanolic Acid Cubic Liquid Crystal Nanoparticle-Based Thermosensitive Gel Attenuates Depression Symptoms in Chronic Unpredictable Mild Stress Rats [PDF]

Zhiqi Shi,1,2,* Qing Wang,1,* Qing Li,1,3 Fan Jia,1,3 Weifeng Xu1 1Wuxi Affiliated Hospital of Nanjing University of Chinese Medicine, Wuxi, Jiangsu, People’s Republic of China; 2Liangxi District Hospital of Traditional Chinese Medicine, Wuxi ...
Wang Q, Li Q, Jia F, Shi Z, Xu W
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Anti-inflammatory activity of oleanolic acid by inhibition of secretory phospholipase a(2)

, 2009
Oleanolic acid, a triterpenoid known for its anti-inflammatory properties, is commonly present in several medicinal plants. The present study evaluated the effect of oleanolic acid on sPLA(2), a key enzyme in inflammatory reactions.
Vishwanath, B. S., Dharmappa, K. K., Mohamed, Riyaz, Raju Venkatesh Kumar, Shivaprasad, H. V., Nataraju, A.   +5 more
core   +1 more source

Integrative Phytochemical, Antioxidant, and NLRP3‐Linked and Anti‐Inflammatory Evaluation of Salvia balansae (Aurès Chemotype): Insights Into Its Safety and Therapeutic Potential

ChemistryOpen, Volume 15, Issue 9, September 2026.
An endemic Aurès chemotype of Salvia balansae emerges as a rich source of luteolin, rosmarinic acid, and other polyphenols with potent antioxidant and NLRP3‐linked anti‐inflammatory activities. Protection against experimental inflammation, favorable enzyme‐modulating properties, and a wide safety margin highlight its promise as a pharmaceutical and ...
Khadra Afaf Bendrihem, Messaoud Hachemi, Mohamed Aimene Mihoubi, Fares Mohamed Amine, Majid Sharifi‐Rad, Dalal Houhou, Rahma Guemmaz, Khaled Kherraz, Azzeddine Zeraib, Assia Abdelmalek, Aicha Mouane, Nour Elhouda Ayeb, Chawki Bensuici, Maria Chikha, Kamel Nagaz, Ayomide Victor Atoki, Mohammed Messaoudi   +16 more
wiley   +1 more source

Comprehensive Chemical and Biological Assessment of Orobanche racemosa Extracts Using Chromatographic, In Vitro, In Silico, and Cell‐Based Techniques

ChemistryOpen, Volume 15, Issue 9, September 2026.
Orobanche racemosa can be considered an effective source of natural bioactive agents in designing functional applications. The growing interest in natural product research as a safer and sustainable alternative to synthetic drugs has triggered this study, which evaluates the chemical profile and biological activity of Orobanche racemosa extracts.
Nilofar Nilofar, Enver Saka, Mehmet Veysi Cetiz, Maria J. Rodrigues, Eliana Fernandes, Luisa Custodio, Evren Yildiztugay, Ismail Yapıcı, Ilhami Gulcin, Esraa A. Elhawary, Omayma A. Eldahshan, Abdel Nasser B. Singab, Carlos L. Cespedes‐Acuna, Gokhan Zengin   +13 more
wiley   +1 more source

Cranberry Pomace Valorization: Composition, Extraction, Bioactivity, and Food Applications

Comprehensive Reviews in Food Science and Food Safety, Volume 25, Issue 5, September 2026.
ABSTRACT Cranberry pomace, the principal solid residue generated during cranberry processing, is increasingly recognized as a compositionally valuable coproduct rather than a waste material. This is particularly relevant in North America, where cranberry production is concentrated in the United States and Canada, the two leading producing countries ...
Ali Ali Redha, Tuba Esatbeyoglu
wiley   +1 more source

Biogenic Silver Nanoparticles Mediated by Phytoconstituents of the Edible Spice Pimpinella anisum: Characterization and In Vitro, In Vivo, and In Silico Biological Evaluation

Journal of Food Science, Volume 91, Issue 9, September 2026.
ABSTRACT This study evaluated the aqueous extract of Pimpinella anisum seeds (AE‐PAS) and its green‐synthesized silver nanoparticles (PA‐AgNPs) using integrated in vitro, in vivo, and in silico approaches. LC–MS analysis identified 26 phytoconstituents, mainly sinapic acid (15.78%), hispidulin (15.35%), caffeic acid (11.09%), and rutin (8.86%).
Ibtissam Laib, Anis Ben Ali, Soundes Guedda, Nardjes Guedda, Naglaa A. Abd‐Elkarim, Yousef Benaissa, Nariman Essmat, Elhafnaoui Lanez, Mohamed F. Abouelenein, Ahmed I. Osman, Alaa Mahfouz, Ahmed K. Rashwan   +11 more
wiley   +1 more source

Naringenin as a Multifunctional Ingredient Targeting Pathways Associated With Skin Inflammaging: Preclinical and Clinical Evidence

Journal of Cosmetic Dermatology, Volume 25, Issue 9, September 2026.
ABSTRACT Background Inflammaging, a sustained state of low‐level inflammatory activity with age, is a driving factor in age‐related changes in skin structure, function, and appearance. By perturbing fundamental biological pathways, inflammaging is a relevant target in skincare and anti‐aging research.
Taylor Oswald, Zixuan Shao, Nicholas Brideau   +2 more
wiley   +1 more source

Preparation and antitumor evaluation of self-assembling oleanolic acid-loaded Pluronic P105/D-α-tocopheryl polyethylene glycol succinate mixed micelles for non-small-cell lung cancer treatment

, 2016
Hao Wu,1–3 Qingxiang Zhong,1,2 Rongling Zhong,4 Houcai Huang,4 Zhi Xia,4 Zhongcheng Ke,1,5 Zhenhai Zhang,1 Jie Song,1,2 Xiaobin Jia1–3 1Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese
Ke ZC, Jia XB, Xia Z, Zhong QX, Zhang ZH, Zhong RL, Song J, Wu H, Huang HC   +8 more
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Hypotensive Effects of the Triterpene Oleanolic Acid for Cardiovascular Prevention

[eng] Background: Hypertension is a highly prevalent chronic disease worldwide and a major cardiovascular risk factor. Oleanolic acid (3β-hydroxy-olea-12-en-28-oic acid) is a widely distributed bioactive pentacyclic triterpenoid with diverse biological
Sureda, A., Tejada, S., Ferriol, P., Pinya, S., Monserrat-Mesquida, M.   +4 more
core   +1 more source

Characterization of functional metabolites in broccoli by‐product using green extraction with supercritical fluids

Journal of the Science of Food and Agriculture, Volume 106, Issue 11, Page 6789-6799, 30 August 2026.
Abstract BACKGROUND The present study aimed to valorize broccoli by‐products (leaves and stems) through the extraction of bioactive compounds using supercritical fluid extraction (SFE). The influence of broccoli variety, plant part and maturation stage on total phenolic content (TPC), antioxidant activity and antimicrobial properties was evaluated ...
Iris Gudiño, Rocío Casquete, María José Benito, María de Guía Córdoba, María Henar Prieto, Alberto Martín   +5 more
wiley   +1 more source