Results 71 to 80 of about 2,519,723 (219)

Inhibition of key enzymes linked to type 2 diabetes by compounds isolated from Aframomum melegueta fruit

Pharmaceutical Biology, 2017
Context: The use of Aframomum melegueta K. Schum. (Zingiberaceae) fruit for treatment of diabetes has recently been established in Nigeria. However, compounds responsible for the antidiabetic action have not been identified.
Aminu Mohammed, Victoria Awolola Gbonjubola, Neil Anthony Koorbanally, Md. Shahidul Islam   +3 more
doaj   +1 more source

Hydrogen Sulfide Application Reduces Postharvest Weight Loss in Tomato Fruit by Promoting Cuticular Wax Accumulation

Future Postharvest and Food, Volume 3, Issue 3, Page 361-370, September 2026.
NaHS‐derived H2S enhances postharvest tomato fruit storability by reducing weight loss, delaying peel wrinkling, and maintaining peel firmness. This response is associated with increased cuticular wax deposition and upregulation of wax biosynthetic and regulatory genes, without marked changes in PME or PG activities. ABSTRACT During postharvest storage,
Yuting Liang, Yi Chen, Zhiman Xu, Manling Wang, Yingying Wei, Shu Jiang, Jianfen Ye, Feng Xu, Jiahui Chen, Christian Chervin, Phebe Ding, Xingfeng Shao   +11 more
wiley   +1 more source

Preparation, characterization, and in vivo pharmacokinetics of nanostructured lipid carriers loaded with oleanolic acid and gentiopicrin

International Journal of Nanomedicine, 2013
Kunchi Zhang, Shaowa Lv, Xiuyan Li, Yufei Feng, Xin Li, Lu Liu, Shuang Li, Yongji Li School of Pharmacy, Heilongjiang University of Traditional Chinese Medicine, Harbin, Heilongjiang Province, People’s Republic of China Background: The purpose of ...
Zhang KC, Lv SW, Li XY, Feng YF, Li X, Liu L, Li S, Li YJ   +7 more
doaj  

Allosterically activating SHP2 by oleanolic acid inhibits STAT3–Th17 axis for ameliorating colitis

Acta Pharmaceutica Sinica B
Src homology 2 domain-containing tyrosine phosphatase 2 (SHP2) is an essential tyrosine phosphatase that is pivotal in regulating various cellular signaling pathways such as cell growth, differentiation, and survival.
Jinbo Hu, Wen Liu, Yi Zou, Chenyang Jiao, Jiazhen Zhu, Qiang Xu, Jianjun Zou, Yang Sun, Wenjie Guo   +8 more
doaj   +1 more source

Oleanolic acid induces mitochondrial-dependent apoptosis and G0/G1 phase arrest in gallbladder cancer cells

, 2015
Huai-Feng Li,1–3,* Xu-An Wang,1–3,* Shan-Shan Xiang,1–3,* Yun-Ping Hu,1–3 Lin Jiang,1–3 Yi-Jun Shu,1–3 Mao-Lan Li,1–3 Xiang-Song Wu,1–3 Fei Zhang,1–3 Yuan-Yuan Ye,1–3 Hao Weng,1–3 Run-Fa ...
Shu YJ, Ye YY, Zhang F, Wu XS, Jiang L, Lu W, Hu YP, Wang XA, Dong Q, Bao RF, Xiang SS, Weng H, Cao Y, Liu YB, Li ML, Li HF   +15 more
core  

Dietary Supplementation With Lily Bulb Core Extract Improves Feed Efficiency, Meat Quality, and Intestinal Health in Yellow‐Feathered Broilers

Food Science &Nutrition, Volume 14, Issue 9, September 2026.
Dietary lily bulb core extract improved feed efficiency, meat quality, and intestinal health in yellow‐feathered broilers. Supplementation at 600 mg/kg produced the most consistent overall benefits, enhancing average daily gain and the feed conversion ratio while reducing cooking loss in both breast and leg muscles.
Jiawei Tan, Jiahui Yin, Xiqing Fan, Linyu Zhang, Chenxia Xia, Shaodi Sun, Xiaoyu Mi, Yunhai Hu, Jianguo Zeng, Wei Xiang, Hongqi Xie   +10 more
wiley   +1 more source

Oleanolic Acid Derivatives as Potential Inhibitors of HIV‑1 Protease

, 2019
Pentacyclic triterpenes, such as oleanolic acid (I), are promising scaffolds for diversification through the use of combinatorial methods to obtain derivatives that improve their biological properties, increasing their bioavailability and enhancing their
Francisco Rivas (1768414), Andres Parra (1768411), Marta Medina-O’Donnell (1768408), Antonio Martinez (111896), Fernando J. Reyes-Zurita (7500863), Mario Cano-Muñoz (7500866), Jose A. Lupiañez (1768417)   +6 more
core   +1 more source

Beneficial vascular effects of oleanolic acid and erythrodiol

, 2021
Trabajo presentado en el 74th European Atherosclerosis Society (EAS) Congress, celebrado en Sevilla (España) del 17 al 20 de abril de 2004.Olive oil of second pressing, so called in Spain "orujo oil" is rich in minor components.
Ruiz-Gutiérrez, Valentina, Rodríguez-Rodríguez, Rosalía, Herrera González, M.   +2 more
core   +1 more source

Oleanolic Acid Promotes the Formation of Probiotic Escherichia coli Nissle 1917 (EcN) Biofilm by Inhibiting Bacterial Motility

Microorganisms
Probiotic biofilms have been beneficial in the fight against infections, restoring the equilibrium of the host’s gut microbiota, and enhancing host health. They are considered a novel strategy for probiotic gut colonization.
Dan Liu, Jingjing Liu, Lei Ran, Zhuo Yang, Yuzhang He, Hongzao Yang, Yuandi Yu, Lizhi Fu, Maixun Zhu, Hongwei Chen   +9 more
doaj   +1 more source

Dual‐Drug‐Loaded Liposomes: Design Strategies, Mechanistic Insights, and Therapeutic Applications in Cancer

MedComm – Biomaterials and Applications, Volume 5, Issue 3, September 2026.
Dual‐drug‐loaded liposomes enable the simultaneous delivery of hydrophilic and hydrophobic therapeutics to tumors, enhancing anticancer efficacy and overcoming multidrug resistance. Through rational formulation design and surface functionalization, these systems improve tumor targeting, modulate efflux mechanisms and EMT, and achieve synergistic ...
Neelam Sinha, Rohan Chand Sahu, Rohit Patil, Dinesh Kumar, Ashish Kumar Agrawal   +4 more
wiley   +1 more source