Results 121 to 130 of about 11,485 (176)

A novel C-3-substituted oleanolic acid benzyl amide derivative exhibits therapeutic potential against influenza A by targeting PA-PB1 interactions and modulating host macrophage inflammation. [PDF]

Acta Pharm Sin B
Lu K, He J, Hong C, Li H, Ruan J, Wang J, Yuan H, Rong B, Yang C, Song G, Liu S.   +10 more
europepmc   +1 more source

The Protective Effect of <i>Boschnikia rossica</i> Extract on Free Radical-Induced Oxidative Damage of Biomolecules and Establishment of a Method for Determining the Content of Oleanolic Acid. [PDF]

Foods
Zhao Z, Jia M, An Y, Bao Y, Zhao Y.
europepmc   +1 more source

Oleanolic Acid Restores Drug Sensitivity in Sorafenib-resistant Hepatocellular Carcinoma: Evidence from <i>In Vitro</i> and <i>In Vivo</i> Studies. [PDF]

J Clin Transl Hepatol
Li T, Shen X, Zhang T, Ren J, Wang W, Wang D, Zhang P.   +6 more
europepmc   +1 more source

Biological Properties of Oleanolic Acid Derivatives Bearing Functionalized Side Chains at C-3. [PDF]

Int J Mol Sci
Fontana G, Badalamenti N, Bruno M, Maggi F, Dell'Annunziata F, Capuano N, Varcamonti M, Zanfardino A.   +7 more
europepmc   +1 more source

New Synthetic Analogs of Natural 5Z,9Z-Dienoic Acids-Hybrid Molecules Based on Oleanolic Acid: Synthesis and Study of Antitumor Activity. [PDF]

Cancers (Basel)
Tuktarova RA, Dzhemileva LU, Dzhemilev UM, D'yakonov VA.   +3 more
europepmc   +1 more source

Preparation and characterization of solidified oleanolic acid–phospholipid complex aiming to improve the dissolution of oleanolic acid

Asian Journal of Pharmaceutical Sciences, 2016
AbstractThe purpose of this study was to prepare the oleanolic acid–phospholipid complex (OA-PC) and then solidify it employing fumed silica by simple solvent evaporation technique to improve dissolution rate of oleanolic acid and oleanolic acid–phospholipid complex.
Qikun Jiang, Ping Du, Tianhong Zhang
exaly   +4 more sources

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Oleanolic acid

Phytochemistry, 2012
Oleanolic acid (3β-hydroxyolean-12-en-28-oic acid) is a pentacyclic triterpenoid compound with a widespread occurrence throughout the plant kingdom. In nature, the compound exists either as a free acid or as an aglycone precursor for triterpenoid saponins, in which it can be linked to one or more sugar chains. Oleanolic acid and its derivatives possess
Jacob Pollier, Alain Goossens
exaly   +3 more sources

Pharmacology of oleanolic acid and ursolic acid

Journal of Ethnopharmacology, 1995
Oleanolic acid and ursolic acid are triterpenoid compounds that exist widely in food, medicinal herbs and other plants. This review summarizes the pharmacological studies on these two triterpenoids. Both oleanolic acid and ursolic acid are effective in protecting against chemically induced liver injury in laboratory animals.
Jie Liu
exaly   +3 more sources

Oleanolic acid and ursolic acid: Research perspectives

Journal of Ethnopharmacology, 2005
Oleanolic acid and ursolic acid are ubiquitous triterpenoids in plant kingdom, medicinal herbs, and are integral part of the human diet. During the last decade over 700 research articles have been published on their research, reflecting tremendous interest and progress in our understanding of these triterpenoids.
Jie Liu
exaly   +3 more sources