Results 11 to 20 of about 5,387 (179)

Oleuropein has hypophagic effects in broiler chicks

Frontiers in Physiology
Oleuropein, a phenolic compound derived from olives, has known glucoregulatory effects in mammalian models but effects in birds are unknown. We investigated effects of dietary supplementation and exogenous administration of oleuropein on broiler chick ...
Usman Sulaiman, Reagan Vaughan, Paul Siegel, Dongmin Liu, Elizabeth Ruth Gilbert, Mark Andrew Cline   +5 more
doaj   +3 more sources

Oleuropein Aglycone Modulates Oxidative Stress and Autophagy-Related Pathways in Human Skeletal Muscle Cells. [PDF]

Biofactors
Oleuropein aglycone activates AMPK/FOXO signaling in skeletal muscle cells, enhancing antioxidant defenses and autophagy. In summary, it improves cellular redox balance and protects muscle cells from stress‐induced early senescence. ABSTRACT A gradual loss of muscle mass and strength increases the risk of falls, frailty and mortality.
Polacchini G, Venerando A, Bigot A, Colitti M.   +3 more
europepmc   +2 more sources

Nephroprotective Potential of Olea europaea Leaf Extract Against Combined Noise and Toluene-Induced Oxidative and Histopathological Renal Injuries in Wistar Rats. [PDF]

Chem Biodivers
ABSTRACT Noise and toluene are environmental stressors that induce oxidative stress and inflammation, contributing to renal dysfunction. This study evaluated the protective effects of Olea europaea leaf extract (OeLE; 40 mg/kg/day) against combined noise‐ and toluene‐induced nephrotoxicity in Wistar rats.
Ben Attia T, Horchani M, Salhi M, Dhifallah Z, Ksentini M, Ben Jannet H, Mhamdi A.   +6 more
europepmc   +2 more sources

Oleuropein ve Kanser

Journal of Nutrition and Dietetics, 2022
Reaktif oksijen türlerindeki artış ve antioksidan kapasitedeki azalmanın birlikteliği organizma organik bileşiklerinde oksidatif modifikasyona neden olmaktadır. Bu oksidatif modifikasyonlar kanseri de içeren birçok patogenezin etiyolojisinde yer almaktadır.
Şerife Akpınar, Gamze Akbulut
openaire   +2 more sources

Beneficial role of oleuropein in sepsis-induced myocardial injury. Possible Involvement of GSK-3β/NF-kB pathway [PDF]

Acta Cirúrgica Brasileira, 2021
Purpose The present study explored the potential therapeutic role of oleuropein in sepsis-induced heart injury along with the role of GSK-3β/NF-kB signaling pathway.
Conghui Xing, Li Xu, Yingjie Yao
doaj   +2 more sources

Structure Properties, Acquisition Protocols, and Biological Activities of Oleuropein Aglycone

Frontiers in Chemistry, 2018
Oleuropein aglycone, which is the major phenolic component of extra virgin olive oil, is gaining popularity and importance in scientific and public communities.
Fangxue Xu, Yujuan Li, Mengmeng Zheng, Xiaozhi Xi, Xuelan Zhang, Chunchao Han   +5 more
doaj   +1 more source

Protective effects of oleuropein against renal injury oxidative damage in alloxan-induced diabetic rats; a histological and biochemical study [PDF]

Journal of Nephropathology, 2017
Background: Oleuropein is a potent antioxidant and free-radical scavenger with antiinflammatory properties. Objectives: In the present study, we evaluated the protective effects of oleuropein on myeloperoxidase (MPO) activity, nitrite, urea, creatinine ...
Hassan Ahmadvand, Gholamreza Shahsavari, Majid Tavafi, Shahrokh Bagheri, Mohamad Reza Moradkhani, Reza Mohammadrezaei Kkorramabadi, Peyman Khosravi, Maryam Jafari, Khadije Zahabi, Reza Eftekhar, Maryam Soleimaninejad, Sanaz Moghadam   +11 more
doaj   +1 more source

Oleuropein Induced Apoptosis in HeLa Cells via a Mitochondrial Apoptotic Cascade Associated With Activation of the c-Jun NH2-Terminal Kinase

Journal of Pharmacological Sciences, 2014
.: Oleuropein could inhibit growth and/or induce apoptosis in several cancer cell lines. In this study, we investigate how oleuropein strongly induces apoptotic cell death in HeLa human cervical carcinoma cells. Oleuropein induced HeLa cells apoptosis as
Jie Yao, Jibing Wu, Xue Yang, Jiaxi Yang, Yuxing Zhang, Linfang Du   +5 more
doaj   +1 more source

Oleuropein Attenuates Lipopolysaccharide-Induced Acute Kidney Injury In Vitro and In Vivo by Regulating Toll-Like Receptor 4 Dimerization

Frontiers in Pharmacology, 2021
Acute kidney injury (AKI) is a common critical illness that involves multiple systems and multiple organs with a rapid decline in kidney function over short period.
Yushun Cui, Yushun Cui, Hongwei Gao, Hongwei Gao, Shan Han, Shan Han, Renyikun Yuan, Renyikun Yuan, Jia He, Jia He, Youqiong Zhuo, Youqiong Zhuo, Yu-Lin Feng, Yu-Lin Feng, Meiwen Tang, Jianfang Feng, Jianfang Feng, Shilin Yang, Shilin Yang   +18 more
doaj   +1 more source

Oleuropein suppresses endometriosis progression and improves the fertility of mice with endometriosis

Journal of Biomedical Science, 2022
Background Endometriosis is an estrogen-dependent inflammatory reproductive disease. Therefore, systematic estrogen depletion and anti-inflammatory drugs are the current treatment for endometriosis.
Yuri Park, Yeon Jean Cho, Nuri Sung, Mi Jin Park, Xiaoming Guan, William E. Gibbons, Bert W. O’Malley, Sang Jun Han   +7 more
doaj   +1 more source