Results 31 to 40 of about 5,725 (181)

Pharmacokinetic Evaluation of Oleuropein from the Olive Tree (Olea europaea)

Nutraceuticals
In this study, the pharmacokinetic (PK) characteristics of oleuropein present in the olive tree (Olea europaea) were determined. We developed and validated a highly sensitive ultra-performance liquid chromatography coupled with tandem mass spectrometry ...
Pradeep Subedi, Rocío Rivera Rodríguez, Pariksha Thapa, Daniel Lantvit, Jeremy James Johnson   +4 more
doaj   +1 more source

Understanding exosomes in facial esthetics and skin aging

Periodontology 2000, EarlyView.
Abstract Background Skin aging is a multifactorial process mediated by intrinsic (genetic and metabolic) and extrinsic (environmental) factors leading to functional and structural deterioration, including wrinkles, loss of collagen and elastin, as well as various pigmentation disorders.
Richard J. Miron, Catherine Davies, Anton Sculean, Paras Ahmad   +3 more
wiley   +1 more source

Impact of oleuropein on Candida albicans and Staphylococcus aureus adhesion and its mediated toxicity in Zebrafish (Danio rerio) embryos

Iranian Journal of Microbiology
Background and Objectives: The rising prevalence of antibiotic resistance and biofilm-associated infections poses significant challenges in clinical settings.
Samira Karzani, Aghil Sharifzadeh, Bahar Nayeri-Fasaei, Ali Reza Khosravi, Jalal Hassan, Aram Sharifi, Ali Pourshaban Shahrestani   +6 more
doaj   +1 more source

ESTIMATION OF ANTIOXIDANT AND ANTITHROMBOTIC EFFECTS OF CRUDE OLEUROPEIN EXTRACTED FROM OLEA EUROPAEA USING THREE DIFFERENT TECHNIQUES [PDF]

Bulletin of Pharmaceutical Sciences. Assiut University
Thromboembolic diseases are becoming more common and leading causes of death and morbidity worldwide. Oleuropein, the phenolic compound found in olive leaves, is well known for its medicinal benefits.
Naglaa Hamdy, Atheer Obaid, Ashwaq Hameed, Hoda Sherkawy, Hanan M. El-Tantawy, Shaimaa Sayer   +5 more
doaj   +1 more source

Oleuropein Degradation Kinetics in Olive Leaf and Its Aqueous Extracts

Antioxidants, 2021
Although olives leaves are currently considered a waste material from oil mills, they have great potential to be transformed into by-products due to their high oleuropein content.
María Esther Martínez-Navarro, Cristina Cebrián-Tarancón, José Oliva, María Rosario Salinas, Gonzalo L. Alonso   +4 more
doaj   +1 more source

Effect of oleuropein on myocardial dysfunction and oxidative stress induced by ischemic-reperfusion injury in isolated rat heart

Journal of Ayurveda and Integrative Medicine, 2016
Background: Studies have reported antioxidant effect of oleuropein in isolated rat heart. Objective: This study was conducted to investigate whether perfusion of isolated rat heart with oleuropein, before induction of ischemia or at the onset of ...
Mansour Esmailidehaj, Shirin Bajoovand, Mohammad Ebrahim Rezvani, Mozhdeh Sherifidehaj, Zahra Hafezimoghadam, Zeynab Hafizibarjin   +5 more
doaj   +1 more source

Molecular descriptor driven QSPR modeling of Papp, TEER and Efflux Ratio from Caco‐2 cells using machine learning for various phytochemicals

Journal of the Science of Food and Agriculture, Volume 106, Issue 11, Page 6606-6616, 30 August 2026.
Abstract BACKGROUND The present study aimed to develop and validate quantitative structure–property relationship (QSPR) models for predicting permeability related bioavailability indicators including apparent permeability (Papp), trans‐epithelial electrical resistance (TEER) and efflux ratio (ER) based on molecular descriptors (n = 5003) of 83 ...
Jin‐Woo Kim, Rixing Cong, Jin‐Soo Park, Keunwan Park, Kyungsu Kang, Soon‐Mi Shim   +5 more
wiley   +1 more source

Development of plant‐derived biomimetic nanoparticles as a novel targeted drug delivery platform

Clinical and Translational Discovery, Volume 6, Issue 4, August 2026.
Plant‐derived biomimetic nanoparticles (PD‐BNPs) represent a sustainable and biocompatible nanoplatform for targeted drug delivery. This review highlights their therapeutic potential, engineering strategies, and translational challenges toward precision nanomedicine applications. Abstract Plant‐derived biomimetic nanoparticles (PD‐BNPs) have emerged as
Jihad Hasan, Asnaf Nihan Shuvo, Md. Rezaul Karim Sheikh, A. Nayeem Faruqui   +3 more
wiley   +1 more source

Applications of Oleuropein

International Journal of Medical Science and Dental Health
One of the most prevalent phenolic compounds found in olive leaves is oleuropein. Numerous studies have demonstrated the biologically significant effects of this compound, including anti-inflammatory, anti-atherogenic, anticancer, antimicrobial, and antiviral effects, which has led to its increased attention in the scientific community.
Shahad Imad Hameed, Maha Khalid Khadhum, Sanaa Imad Hameed, Saif Ali Mohammed Hussein   +3 more
openaire   +1 more source

Effect of Oleuropein on the Gene Expression of Brain-derived Neurotrophic Factor, Stress Oxidative, and Spatial Memory Impairment Caused by Scopolamine in Male Rats

Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum, 2021
Background and Objectives: Oleuropein is an important phenolic compound found in olive leaves that has important pharmacological functions in the central nervous system and neuroprotective effects in vitro and in vivo conditions. This study was conducted
Gelavij Mahnoodi, Azam Moshfegh
doaj