Results 51 to 60 of about 5,725 (181)

In silico prediction and structural characterization of multifunctional bioactive peptides released from olive proteins

Journal of the Science of Food and Agriculture, Volume 106, Issue 9, Page 5463-5482, July 2026.
Abstract BACKGROUND Olive (Olea europaea L.) byproducts, such as seeds and leaves, are abundant agro‐industrial residues and represent underexplored protein sources with potential health relevance. However, the repertoire of bioactive peptides that may be released from olive proteins during gastrointestinal digestion remains poorly characterized.
Teresa Gonzalez‐de la Rosa, Luna Barrera‐Chamorro, Africa Fernandez‐Prior, Elvira Marquez‐Paradas, Maria Torrecillas‐Lopez, Fernando Rivero‐Pino, Sergio Montserrat‐de la Paz   +6 more
wiley   +1 more source

Recent Advances in the Use of Natural Deep Eutectic Solvents for Natural Product Sample Preparation: Focus on Purification, Characterization, and Sustainability

Journal of Separation Science, Volume 49, Issue 7, July 2026.
ABSTRACT This review examines recent advances in the use of natural deep eutectic solvents (NaDES) for natural product sample preparation, with emphasis on extraction, purification, analytical compatibility, and sustainability. NaDES emerge as versatile, tunable, and biocompatible media that enhance the recovery and stability of diverse phytochemicals ...
Valeria Cedeño‐Fierro, Juan Felipe Grisales‐Mejía, Harlen Gerardo Torres Castañeda, Jose A. Mendiola   +3 more
wiley   +1 more source

A Comparative Study of Oleuropein Extraction from Wild Olive Leaves (Olea europea subsp. oleaster, Hoffmanns. & Link), Its Gastrointestinal Stability, and Biological Potential

Applied Sciences
Olive leaves are the richest source of phenolic compounds, particularly oleuropein, which has many beneficial effects on human health. This study compares the effect of three extraction techniques: ultrasonic-solvent extraction, microwave-assisted ...
Barbara Soldo, Tea Bilušić, Jasminka Giacometti, Ivica Ljubenkov, Vedrana Čikeš Čulić, Andre Bratanić, Perica Bošković, Ivana Šola, Krunoslav Ilić   +8 more
doaj   +1 more source

Natural Products as Modulators of ABC Transporters in Breast Cancer

Phytotherapy Research, Volume 40, Issue 7, Page 4611-4637, July 2026.
ABSTRACT Breast cancer remains a significant global health challenge, with high incidence and mortality rates despite advancements in early detection and treatment. Multidrug resistance (MDR), particularly in aggressive subtypes like triple‐negative breast cancer (TNBC), continues to hinder effective therapy.
Yoganishalini Sagadevan, Reyhaneh Farghadani, Ammu K. Radhakrishnan   +2 more
wiley   +1 more source

Anti-Diabetic Effects of Oleuropein

Metabolites
Background/Objectives: Oleuropein, a secoiridoid polyphenol found in olive oil as well as the fruit and leaves of the olive tree, has been reported to have antioxidant, cardioprotective, anti-inflammatory, anti-cancer, and anti-diabetic properties. Type 2 diabetes mellitus (TD2M) is a chronic metabolic disease characterized by impaired insulin action ...
Michael Iantomasi, Matthew Terzo, Evangelia Tsiani   +2 more
openaire   +3 more sources

Olive oil's bitter principle reverses acquired autoresistance to trastuzumab (Herceptin™) in HER2-overexpressing breast cancer cells

BMC Cancer, 2007
Background A low incidence of breast cancer in the Mediterranean basin suggests that a high consumption of Extra Virgin Olive Oil (EVOO) might confer this benefit.
Brunet Joan, Colomer Ramon, Vazquez-Martin Alejandro, Menendez Javier A, Carrasco-Pancorbo Alegria, Garcia-Villalba Rocio, Fernandez-Gutierrez Alberto, Segura-Carretero Antonio   +7 more
doaj   +1 more source

Updates on Mediterranean diet and health status: active ingredients and pharmacological mechanisms

British Journal of Pharmacology, Volume 183, Issue 13, Page 3484-3502, July 2026.
The Mediterranean diet (MedDiet) is among the most extensively studied dietary patterns and has been consistently associated with reduced risk of all‐cause mortality, cardiovascular disease, metabolic disorders, cognitive decline and several types of cancers.
Lukas Schwingshackl, Jakub Morze, Sabina Wallerer, Georg Hoffmann   +3 more
wiley   +1 more source

The Use of Oleuropein on Myocardium

, 2010
Publisher Summary The olive products constitute a rich source of polyphenols like oleuropein and its derivatives, such as hydroxytyrosol, which have the ability to scavenge free radicals and inhibit the chemical oxidation of low-density lipoproteins.
Ioanna Andreadou, Efstathios K. Iliodromitis, Emmanuel Mikros, Alexios-Leandros Skaltsounis, Dimitrios Th. Kremastinos   +4 more
openaire   +3 more sources

Antifungal Activity of Oleuropein against Candida albicans—The In Vitro Study

Molecules, 2016
In the present study we investigated activity of oleuropein, a complex phenol present in large quantities in olive tree products, against opportunistic fungal pathogen Candida albicans.
Nataša Zorić, Nevenka Kopjar, Ivan Bobnjarić, Igor Horvat, Siniša Tomić, Ivan Kosalec   +5 more
doaj   +1 more source

Advances in Eco‐Friendly Extraction of Fruit Bioactive Compounds: Technologies, Challenges and Future Directions

Analytical Science Advances, Volume 7, Issue 1, June 2026.
Fruit bioactive compounds offer antioxidant, anti‐inflammatory, and preventive benefits, yet extraction is hindered by poor solubility and conventional methods using toxic solvents and high energy. This review evaluates traditional and advanced eco‐friendly technologies, highlighting efficiency, selectivity, and sustainability.
Abadi Gebreyesus Hndeya, Desta Berhe Sbhatu, Gebreselema Gebreyohannes   +2 more
wiley   +1 more source