Results 21 to 30 of about 42,020 (371)

Development and in vivo validation of small interfering RNAs targeting NOX3 to prevent sensorineural hearing loss

open access: yesFrontiers in Neurology, 2022
The reactive oxygen species (ROS)-generating enzyme NOX3 has recently been implicated in the pathophysiology of several acquired forms of sensorineural hearing loss, including cisplatin-, noise- and age-related hearing loss.
German Nacher-Soler   +8 more
doaj   +1 more source

Why human olfaction should not be modeled on theories and tasks of vision

open access: yesFrontiers in Psychology, 2023
In this paper we analyze some key concepts and problems in olfaction and argue that many concepts borrowed from vision are not helpful in elucidating the functions of human olfaction. This is illustrated with several examples.
Per Møller, Egon P. Köster
doaj   +1 more source

An Automated Canine Line-Up for Detection Dog Research

open access: yesFrontiers in Veterinary Science, 2021
Currently, there is a need to develop technology that facilitates and improves detection dog research. The aim of this research was to develop an automated computer-driven olfactory line-up task. The apparatus consisted of three olfactometers.
Edgar O. Aviles-Rosa   +3 more
doaj   +1 more source

Local Cisplatin Delivery in Mouse Reliably Models Sensorineural Ototoxicity Without Systemic Adverse Effects

open access: yesFrontiers in Cellular Neuroscience, 2021
Cisplatin is a lifesaving chemotherapeutic drug with marked ototoxic adverse effects. Cisplatin-induced hearing loss affects a significant part of cancer-surviving patients and is an unmet clinical need with important socioeconomic consequences ...
German Nacher-Soler   +10 more
doaj   +1 more source

The appearance of phagocytic microglia in the postnatal brain of Niemann Pick type C mice is developmentally regulated and underscores shortfalls in fine odor discrimination

open access: yesJournal of Cellular Physiology, Volume 237, Issue 12, Page 4563-4579, December 2022., 2022
Abstract The loss of NPC1 or NPC2 function results in cholesterol and sphingolipid dyshomeostasis that impairs developmental trajectories, predisposing the postnatal brain to the appearance of pathological signs, including progressive and stereotyped Purkinje cell loss and microgliosis.
Alessandro Rava   +8 more
wiley   +1 more source

Ontogenetic shifts in olfactory rosette morphology of the sockeye salmon, Oncorhynchus nerka

open access: yesJournal of Morphology, Volume 284, Issue 1, January 2023., 2023
Scanning electron microscope images of sockeye salmon olfactory rosette. Olfactory rosette size linearly increases with lamellae number throughout ontogeny. The complexity of the rosette, including the distribution of sensory and nonsensory epithelia, and the appearance of secondary lamellar folding, varies between fry and adult life stages.
Sarah E. Rheinsmith   +3 more
wiley   +1 more source

The RUB cage: Respiration-Ultrasonic vocalizations-Behavior acquisition set-up for assessing emotional memory in rats

open access: yesFrontiers in Behavioral Neuroscience, 2011
In animals, emotional memory is classically assessed through pavlovian fear conditioning in which a neutral novel stimulus (conditioned stimulus) is paired with an aversive unconditioned stimulus.
Chloe eHegoburu   +11 more
doaj   +1 more source

Astrocytic Regulation of Neural Circuits Underlying Behaviors

open access: yesCells, 2021
Astrocytes, characterized by a satellite-like morphology, are the most abundant type of glia in the central nervous system. Their main functions have been thought to be limited to providing homeostatic support for neurons, but recent studies have ...
Sun-Nyoung Hwang   +3 more
doaj   +1 more source

Long‐Term COVID‐19 Smell and Taste Disorders Differ Significantly from Other Post‐Infectious Cases

open access: yesThe Laryngoscope, Volume 133, Issue 1, Page 169-174, January 2023., 2023
Introduction COVID‐19 is causing a wide range of clinical manifestations. Severe complications and long‐lasting sequelae have been identified. Thus, olfactory disorders are reported in up to 86% of cases in mild and moderate COVID‐19 infections. We present the first study comparing simple and complex post‐COVID‐19 cases with matched non‐COVID‐19 post ...
Dovile Stankevice   +3 more
wiley   +1 more source

Global Coverage Measurement Planning Strategies for Mobile Robots Equipped with a Remote Gas Sensor

open access: yesSensors, 2015
The problem of gas detection is relevant to many real-world applications, such as leak detection in industrial settings and landfill monitoring. In this paper, we address the problem of gas detection in large areas with a mobile robotic platform equipped
Muhammad Asif Arain   +4 more
doaj   +1 more source

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