Results 101 to 110 of about 362,207 (293)
S3RL: Enhancing Spatial Single‐Cell Transcriptomics With Separable Representation Learning
Advanced Science, EarlyView.Separable Spatial Representation Learning (S3RL) is introduced to enhance the reconstruction of spatial transcriptomic landscapes by disentangling spatial structure and gene expression semantics. By integrating multimodal inputs with graph‐based representation learning and hyperspherical prototype modeling, S3RL enables high‐fidelity spatial domain ...
Laiyi Fu +6 more
wiley +1 more source
Orientation in space using the sense of smell [PDF]
, 2010 Several studies reported that respiration interacts with olfactory perception. Therefore, in the pilot study of this experiment series human breathing was investigated during an olfactory experiment.
Kleemann, Anna Maria
core
, 2020 We perceive smells as perduring complex entities within a distal array that might be conceived of as smellscapes. However, the philosophical orthodoxy of Odor Theories has been to deny that smells are perceived as having a distal location.
Young, Benjamin D.
core
Influence of blood meal on the responsiveness of olfactory receptor neurons in antennal sensilla trichodea of the yellow fever mosquito, Aedes aegypti [PDF]
, 2010 In female Aedes aegypti L. mosquitoes, a blood meal induces physiological and behavioral changes. Previous studies have shown that olfactory receptor neurons (ORNs) housed in grooved peg sensilla on the antennae of Ae.
Hansson, Bill +3 more
core +1 more source
GPCRs in CAR‐T Cell Immunotherapy: Expanding the Target Landscape and Enhancing Therapeutic Efficacy
Advanced Science, EarlyView.Chimeric antigen receptor T cell therapy faces dual challenges of target scarcity and an immunosuppressive microenvironment in solid tumors. This review highlights how G protein‐coupled receptors can serve as both novel targets to expand the therapeutic scope and functional modules to enhance CAR‐T cell efficacy.
Zhuoqun Liu +11 more
wiley +1 more source
The task of olfactory search is ubiquitous in nature and in technology, from animals in the quest of food or of a mating partner, to robots searching for the source of hazardous fumes in a chemical plant. Here, we focus on the algorithmic approach to this task: we systematically review the different olfactory search strategies.
Celani, Antonio, Panizon, Emanuele
openaire +2 more sources
Advanced Science, EarlyView.Emerging evidence suggests that intraneuronal Aβ accumulation represents an early pathogenic event in Alzheimer's disease (AD). Using Drosophila AD model, this study shows that a nonsecreted serine protease Yip7 physically interacts with Aβ. This causes intraneuronal Aβ accumulation but surprisingly reduces the associated neurotoxicity, arguing that ...
Jingyun Su +4 more
wiley +1 more source
Advanced Science, EarlyView.Ru–Mn composite nanozymes are engineered to mimic dual‐enzyme cascade catalysis, enabling efficient ROS clearance and neuroinflammation suppression. In collagenase‐ and autologous blood‐induced ICH mouse models, intranasal and intravenous administration reduced hematoma volume, preserved BBB integrity, and improved neurological recovery.
Zhongxin Duan +8 more
wiley +1 more source
What Is and Could Become Olfactory Aesthetics?
ESPESIntroduction into a thematic symposium on Olfactory Aesthetics published in ESPES. The Slovak Journal of Aesthetics (Vol. 13 No 1, 2024).
Mădălina Diaconu
doaj +1 more source
IEEE Access, 2019 Olfactory dysfunction is related to several clinical neurodegenerative diseases, such as Alzheimer's disease, multiple sclerosis, degenerative ataxias, Parkinson's disease, and so on.
Kuo-Wei Wang +8 more
doaj +1 more source